1. Anti-infection
    Autophagy
  2. Fungal
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    Mitophagy
    Antibiotic
  3. Clioquinol

Clioquinol (Synonyms: Iodochlorhydroxyquin)

Cat. No.: HY-14603 Purity: ≥98.0%
Handling Instructions

Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic.

For research use only. We do not sell to patients.

Clioquinol Chemical Structure

Clioquinol Chemical Structure

CAS No. : 130-26-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Estimated Time of Arrival: December 31
5 g USD 108 In-stock
Estimated Time of Arrival: December 31
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50 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Customer Review

Description

Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic[1].

In Vitro

Clioquinol (0.01-1000 uM; 72 hours) shows anticancer activity against U251, and MV-4-11 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: The MV-4-11, and U-251 cell lines
Concentration: 0.01, 0.1, 1, 10, 100, 1000 uM
Incubation Time: 72 hours
Result: The IC50s were 32 and 46 μM in U251 and MV-4-11 cells, respectively.
Clinical Trial
Molecular Weight

305.50

Formula

C₉H₅ClINO

CAS No.
SMILES

ClC1=C(C=CC=N2)C2=C(O)C(I)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 53.33 mg/mL (174.57 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2733 mL 16.3666 mL 32.7332 mL
5 mM 0.6547 mL 3.2733 mL 6.5466 mL
10 mM 0.3273 mL 1.6367 mL 3.2733 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.08 mg/mL (6.81 mM); Suspended solution; Need ultrasonic and warming

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.81 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: ≥98.0%

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Keywords:

ClioquinolIodochlorhydroxyquinFungalAutophagyMitophagyAntibioticMitochondrial AutophagyInhibitorinhibitorinhibit

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Product Name:
Clioquinol
Cat. No.:
HY-14603
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