4 Results for "

abstinence syndrome

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "abstinence syndrome" in MCE Product Catalog:

Cat. No.: HY-P1248
CAS No.: 99566-27-5
Synonyms: NPFF
Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, is a NPFF1 and NPFF2 receptors agonist with Ki values of 2.82 nM and 0.21 nM, respectively. Neuropeptide FF induces abstinence syndrome, exerts antiopioid and analgesic effects, releases via calcium-dependent mechanisms from rat spinal cord, regulates memory, autonomic function, and neuroendocrine function, modulates pain and opioid antinociception, reduces food intake, stimulates water intake, alters cardiovascular parameters, and shows differential activity in hypothalamic paraventricular nucleus neurons. Neuropeptide FF is present in mammalian central nervous system and periphery, with NPFF-immunoreactivity increases in rat cerebrospinal fluid during opiate tolerance, and its NPFF gene and NPFF-R2 gene are up-regulated in rat spinal cord and dorsal root ganglia during peripheral inflammation. Neuropeptide FF can be used for the research of opioid tolerance, morphine-induced analgesia, abstinence syndrome, pain, hypertension, nociception, inflammatory pain, and neuropathic pain .
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Cat. No.: HY-119174
CAS No.: 66537-55-1
Research Areas:  

Neurological Disease

MK771 is a thyrotrophin-releasing hormone analog. MK771 induces blinking and forepaw licking. MK771 has the potential for the research of morphine abstinence syndrome .
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Cat. No.: HY-122133
CAS No.: 47739-68-4
Target:  

Others

Research Areas:  

Metabolic Disease

CI 750 is an orally active antidiarrheal agent. CI 750 exhibits antidiarrheal activity in monkeys and rats. CI 750 can be used for the research of diarrhea .
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Cat. No.: HY-W274652
CAS No.: 5555-22-6
Synonyms: IEM-1770
Target:  

iGluR Drug Derivative

Research Areas:  

Neurological Disease

Benzylaspartic acid (IEM-1770), a derivative of aspartic acid, is a NMDA agonist. Benzylaspartic acid has antidepressant activity. Benzylaspartic acid blocks alcohol-abstinence syndrome (AAS) development in chronic alcohol drinking rat models. Benzylaspartic acid can be used for depression research .
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