66537-55-1
66537-55-1
Chemical Structure
MK771
- CAS No.: 66537-55-1
- Formula:C16H22N6O4S
- Molecular Weight:394.45
IUPAC Name: (S)-3-(((S)-6-oxopiperidine-2-carbonyl)-L-histidyl)thiazolidine-4-carboxamide
InChIKey: OGUDACTYCTVDNZ-SDDRHHMPSA-N
SMILES: O=C(N[C@H](C(N1CSC[C@@H]1C(N)=O)=O)CC2=CNC=N2)[C@@H](N3)CCCC3=O
Biological Activity: MK771 is a thyrotrophin-releasing hormone analog. MK771 induces blinking and forepaw licking. MK771 has the potential for the research of morphine abstinence syndrome[1][2].
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MK771 | MK771 is a thyrotrophin-releasing hormone analog. MK771 induces blinking and forepaw licking. MK771 has the potential for the research of morphine abstinence syndrome. | |||||||||||||||||||||
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References
- [1]. McCreary AC, et al. The thyrotrophin-releasing hormone analogue MK771 induces tic-like behaviours: the effects of dopamine D1 and D2 receptor antagonists. Eur J Pharmacol. 1999 Mar 12;369(1):1-9. [Content Brief]
- [2]. Bhargava HN, et al. Comparative effects of thyrotropin releasing hormone, MK-771 and DN-1417 on morphine abstinence syndrome. Psychopharmacology (Berl). 1985;87(2):141-6. [Content Brief]
