acetylated lysine

By Targets:	Biochemical Assay Reagents (1) Endogenous Metabolite (6) Epigenetic Reader Domain (4) ERK (1) Histone Acetyltransferase (1) Isotope-Labeled Compounds (1) Microtubule/Tubulin (1) Reference Standards (1)
By Research Areas:	Cancer (5) Metabolic Disease (5)

Targets Recommended: WNK Kinase

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-145550

Amredobresib BI894999	Epigenetic Reader Domain	Cancer
Amredobresib (BI894999) is an orally active BET inhibitor. Amredobresib inhibits the binding of BRD4-BD1 and BRD4-BD2 bromodomains to acetylated histones with IC₅₀ values of 5 nM and 41 nM, respectively. Amredobresib exhibits anticancer activity against acute myeloid leukemia (AML) and NUT cancer .

HY-13032B

Molibresib besylate Maximum Cited Publications 21 Publications Verification GSK 525762C; I-BET 762 besylate	Epigenetic Reader Domain ERK	Cancer
Molibresib besylate (GSK 525762C; I-BET 762 besylate) is an orally active pan-BET inhibitor that targets and binds to BRD2, BRD3, BRD4 and BRDT. By competitively occupying acetylated lysine binding sites, Molibresib besylate disrupts the interaction between BET proteins and chromatin, thereby effectively inhibiting MYC expression and target gene transcription. Molibresib besylate exhibits broad antiproliferative activity, which not only inhibits cancer cell growth and induces growth arrest, but also downregulates mitosis-related genes and upregulates the level of p-ERK1/2. When combined with MEK inhibitors, Molibresib besylate shows a significant synergistic effect, reduces tumor burden in mouse models of leukemia, modulates the immune microenvironment and prolongs survival. Molibresib besylate is widely applicable to research related to acute myeloid leukemia, multiple myeloma, triple-negative breast cancer, small-cell lung cancer and various advanced refractory solid tumors .

HY-W048838

**Acetyl-L-lysine** 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426

Nepsilon-Acetyl-L-lysine 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-154818

Bovine Serum Albumin, Acetylated Ac-BSA	Biochemical Assay Reagents	Others
Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

HY-W048838R

Acetyl-L-lysine (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426S

*Nepsilon-acetyl-L-lysine-d8*	Isotope-Labeled Compounds Endogenous Metabolite	Others
Nepsilon-acetyl-L-lysine-d₈ is the deuterium labeled Nepsilon-Acetyl-L-lysine. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-113426R

*Nepsilon-Acetyl-L-lysine* (Standard)**	Endogenous Metabolite	Metabolic Disease
Nepsilon-Acetyl-L-lysine (Standard) is the analytical standard of Nepsilon-Acetyl-L-lysine. This product is intended for research and analytical applications. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-170226

BET-IN-28	Epigenetic Reader Domain	Cancer
BET-IN-28 (Compound 44) is a highly potent inhibitor of bromodomain and extra-terminal domain (BET), with an IC₅₀ value of 4.47 nM against BRD4-BD1. BET-IN-28 blocks the interaction between BET proteins and N-acetylated lysine residues on histone tails, down-regulates certain genes. BET-IN-28 can be used for hematological malignancies and solid tumors study .

HY-E71022

Trypsin Acetylated, Bovine	Endogenous Metabolite	Metabolic Disease
Trypsin Acetylated, Bovine (EC 3.4.21.4) is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyses proteins. Trypsin is produced in the pancreas as the inactive protease trypsinogen. Trypsin cleaves peptide chains mainly at the carboxyl side of the amino acids lysine or arginine, except when either is followed by proline.

HY-121009

CCT077791	Histone Acetyltransferase Microtubule/Tubulin	Cancer
CCT077791 is a PCAF (IC₅₀: 7.3 μM (FlashPlate); 2.2 μM (Filter assay)) and p300 histone acetyltransferase inhibitor. CCT077791 reduces total acetylation of histones H3 and H4, levels of specific acetylated lysine marks, and acetylation of α-tubulin. CCT077791 can be used in the research of colorectal cancer .

HY-155891

BET-IN-18	Epigenetic Reader Domain	Cancer
BET-IN-18 (Compound 3) is a pan-BET bromodomain small-molecule inhibitor, with K_i values of 0.69 μM and 0.37 μM, and K_d values of 1.6 μM and 8.4 μM against BrdT (1) and Brd4 (1) bromodomains, respectively. BET-IN-18 potently and competitively inhibits the binding of the known BET inhibitor (+)-JQ1 (HY-13030) to Brd4 (1) and BrdT (1), with IC₅₀ values of 1.0 μM and 2.3 μM, respectively. BET-IN-18 also competitively inhibits the binding of acetylated histone substrates to Brd4 (1) (IC₅₀ = 0.90 μM). BET-IN-18 can be used in the research of multiple myeloma .

Cat. No.	상품명	Type

HY-154818

Bovine Serum Albumin, Acetylated Ac-BSA	Biochemical Assay Reagents
Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

Bovine Serum Albumin, Acetylated

Ac-BSA

Biochemical Assay Reagents

Bovine Serum Albumin, Acetylated (Ac-BSA) is a polypeptide of known structure with strong antigenicity. Bovine Serum Albumin, Acetylated produced a significant immune response, validating the accuracy and reliability of the experimental method. Bovine Serum Albumin, Acetylated can be used as a positive control substance in ELISA or WB experiments, and can be used in experiments with acetylated lysine monoclonal or polyclonal antibodies. Bovine Serum Albumin, Acetylated also improves encapsulation efficiency at low concentrations of PLGA, a polymer for biopharmaceutical delivery with biocompatibility, degradability, and controlled release properties .

Cat. No.	상품명	Category	Target	Chemical Structure

HY-W048838

**Acetyl-L-lysine** 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426

Nepsilon-Acetyl-L-lysine 1 Publications Verification	Classification of Application Fields Other Diseases Amino acids Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

HY-W048838R

Acetyl-L-lysine (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-113426R

*Nepsilon-Acetyl-L-lysine* (Standard)**	Amino acids Endogenous metabolite Source Classification	Endogenous Metabolite
Nepsilon-Acetyl-L-lysine (Standard) is the analytical standard of Nepsilon-Acetyl-L-lysine. This product is intended for research and analytical applications. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

Cat. No.	상품명	Chemical Structure

HY-113426S

*Nepsilon-acetyl-L-lysine-d8*
Nepsilon-acetyl-L-lysine-d₈ is the deuterium labeled Nepsilon-Acetyl-L-lysine. Nepsilon-Acetyl-L-lysine, an endogenous metabolite, is an R-chain N-acetylated α amino acid .

Host:	Mouse (2) Rabbit (1)
Reactivity:	Species independent (3)
Application:	IHC-P (3) ICC/IF (2) IF-Tissue (3) IP (1) IHC-F (2) WB (1) ChIP (1) FC (2)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	상품명	Application	Reactivity	Image

HY-P83733

	Acetylated-Lysine Antibody (YA3463) 1 Publications Verification acetylated-lysine Antibody	WB, IHC-P, IP, ChIP, IF-Tissue	Species independent
	Acetylated-Lysine Antibody (YA3463) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Acetylated-Lysine.

HY-P86733

	Acetyl Lysine Antibody (YA6425) acetylated lysine; Acetyllysine; Ac-lysine; Ac lysine; Ac-K; Ac K; Ac-Lys; Ac Lys; acetyl-lysine; acetyl Lys; Ac-lysine;	IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Species independent
	Acetyl Lysine Antibody (YA6425) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Acetyl Lysine.

HY-P86733A

	Acetyl Lysine Antibody (YA6425)(PBS only) acetylated lysine; Acetyllysine; Ac-lysine; Ac lysine; Ac-K; Ac K; Ac-Lys; Ac Lys; acetyl-lysine; acetyl Lys; Ac-lysine;	IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Species independent
	Acetyl Lysine Antibody (YA6425) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Acetyl Lysine.

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acetylated lysine

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