173 Results for "

anthraquinone

" in MedChemExpress (MCE) Product Catalog:
Products (173)

173 Results for "anthraquinone" in MCE Product Catalog:

42
42 Publications Verification
Cat. No.: HY-14393
CAS No.: 518-82-1
Purity:  99.25%
Synonyms: Frangula emodin
Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction . Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects . Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice .
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18
18 Cited Publications
Cat. No.: HY-N0105
CAS No.: 478-43-3
Synonyms: Rheic Acid; Rhubarb yellow; Monorhein
Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects [1] .
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10
10 Cited Publications
Cat. No.: HY-120601
CAS No.: 130-22-3
Purity:  ≥95.0%
Synonyms: ARS sodium
Target:  

Fluorescent Dye

Research Areas:  

Others

Alizarin Red S sodium is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S sodium can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S sodium can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm .
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10
10 Cited Publications
Cat. No.: HY-120601A
CAS No.: 83-61-4
Synonyms: ARS
Target:  

Fluorescent Dye

Research Areas:  

Others

Alizarin Red S (ARS) is an anthraquinone derivative dye. When combined with cations such as calcium ions, the functional group of Alizarin Red S can form a coordination bond with the cation through the oxygen atom to show orange-red fluorescence. Alizarin Red S can be used for screening of calcium compounds in synovial fluid and detecting osteoblast differentiation, and can also be used for bone staining in mice. Excitation/emission wavelength: 500/570 nm .
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10
10 Cited Publications
Cat. No.: HY-N0108
CAS No.: 521-61-9
Synonyms: Parietin; Rheochrysidin
Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells .
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9
9 Cited Publications
Cat. No.: HY-N0123
CAS No.: 1415-73-2
Synonyms: Barbaloin-A
Aloin (Aloin-A; Barbaloin-A) is a natural anti-tumor anthraquinone glycoside with iron chelating activity. Aloin induces the differentiation of MC3T3-E1 cells into osteoblasts through MAPK-mediated Wnt and Bmp signaling pathways. Alkaline phosphatase (ALP) is an early marker of osteoblast differentiation, and the activity of ALP is also enhanced by Aloin. Aloin also reduces brain edema, reduces blood-brain barrier disruption and improves cortical impact injuries. Aloin is used in research into osteoporosis and traumatic brain injury (TBI) .
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7
7 Cited Publications
Cat. No.: HY-N0283
CAS No.: 13739-02-1
Synonyms: Diacerhein; Diacetylrhein
Diacerein (Diacerhein), an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling. Diacerein is an anti-inflammatory and anti-rheumatic drug. Diacerein can relieve bronchospasm and control airway inflammation in asthmatic mice. Diacerein has the potential for slow acting drug in osteoarthritis (SYSADOA) research .
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6
6 Cited Publications
Cat. No.: HY-13595
CAS No.: 481-74-3
Purity:  99.77%
Synonyms: Chrysophanic acid
Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
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6
6 Cited Publications
Cat. No.: HY-N0365
CAS No.: 81-27-6
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC50=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC50s of 1.9 μM and 5.3 μM, respectively .
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3
3 Cited Publications
Cat. No.: HY-N0354
CAS No.: 84-65-1
Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis .
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3
3 Cited Publications
Cat. No.: HY-125815
CAS No.: 13324-20-4
Purity:  ≥97.0%
Reactive Blue 4 is an anthraquinone dye used extensively in the textile industry. Reactive Blue 4 is a single colorimetric chemosensor for sequential determination of multiple analytes with different optical responses in aqueous media .
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3
3 Cited Publications
Cat. No.: HY-135954
CAS No.: 2310262-10-1
Purity:  99.34%
PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 has antidiabetic, anticancer and anti-allergic activity .
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3
3 Cited Publications
Cat. No.: HY-135954A
CAS No.: 2310262-11-2
Purity:  99.72%
PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 hydrochloride potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 hydrochloride has antidiabetic, anticancer and anti-allergic activity .
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2
2 Cited Publications
Cat. No.: HY-N0311
CAS No.: 23313-21-5
Emodin-8-glucoside is an anthraquinone derivative that can be isolated from Aloe vera. Emodin-8-glucoside is the inhibitor for MAPK with an inhibition constant of 430.14 pM. Emodin-8-glucoside exhibits moderate inhibitory activity against rat lens aldose reductase (ALAR) and topoisomerases II with IC50s of 14.4 μM and 66 μM. Emodin-8-glucoside exhibits antioxidant, anti-inflammatory and anti-fibrotic activities. Emodin-8-glucoside can cross the blood brain barrier .
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1
1 Cited Publications
Cat. No.: HY-N0571
CAS No.: 81-54-9
Purpurin is a natural anthraquinone compound from Rubia cordifolia L.. Purpurin has antidepressant-like effects .
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1
1 Cited Publications
Cat. No.: HY-129042
CAS No.: 84166-13-2
Purity:  72%
Cibacron Blue 3G-A is an anthraquinone dye, inhibits the R46 β-lactamase with a Ki value of 1.2 uM .
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1
1 Cited Publications
Cat. No.: HY-N0495
CAS No.: 38412-46-3
Synonyms: Aloenin A
Aloenin (Aloenin A) is a kind of natural product, has effective clearing and free radical activity, and has moderate inhibitory activity on β-secretion (BACE) (IC50=14.95 μg/mL). Aloenin suppresses peritoneal hypertrophy in large rats and suppresses its release.
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1
1 Cited Publications
Cat. No.: HY-119739
CAS No.: 602-06-2
Purity:  97.0%
Skyrin is an anthraquinone compound that can be isolated from almond fruit. Skyrin is a receptor-selective glucagon antagonist. Skyrin can inhibit the growth of tumor cells .
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1
1 Cited Publications
Cat. No.: HY-N0261
CAS No.: 67979-25-3
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation .
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Cat. No.: HY-D0331
CAS No.: 2580-78-1
Reactive Blue 19 is an anthraquinone dye that can be used in the textile industry .
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