84-65-1
84-65-1
Chemical Structure
Anthraquinone
- CAS No.: 84-65-1
- Formula:C14H8O2
- Molecular Weight:208.22
IUPAC Name: anthracene-9,10-dione
InChIKey: RZVHIXYEVGDQDX-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)C(C3=CC=CC=C13)=O
Biological Activity: Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Anthraquinone | 98.84% | Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis. | ||||||||||||||||||||
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Anthraquinone (Standard) | ≥98% | Anthraquinone (Standard) is the analytical standard of Anthraquinone. This product is intended for research and analytical applications. Anthraquinone is used as a precursor for dye formation. | ||||||||||||||||||||
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Anthraquinone-d8 | Anthraquinone-d8 is the deuterium labeled Anthraquinone. Anthraquinone is used as a precursor for dye formation. | |||||||||||||||||||||
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Dibenzosuberone | 99.84% | Dibenzosuberone is a tricyclic compound, commonly referred to as a tricyclic antidepressant (TCA), and is widely used in research on migraine, tension-type headache, anxiety disorder and schizophrenia. Dibenzosuberone also serves as a key intermediate for the synthesis of various active pharmaceutical ingredients (APIs) (e.g., amitriptyline (HY-B0527), nortriptyline (HY-118620), nortriptyline or cyproheptadine (HY-B1622)). | ||||||||||||||||||||
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Alizarin | 99.48% | Alizarin is a natural dye. Alizarin can be extracted from the roots of madder plant. Alizarin activates AMPK and VEGFR2/eNOS pathway. Alizarin regulates PI3K/Akt and inhibits NF-κB pathway. Alizarin enhances CYP1A1 enzyme activity. Alizarin has protective effects on hypertension and vascular endothelial dysfunction. Alizarin has anti-tumor activity against multiple cancers including pancreatic cancer, breast cancer, osteosarcoma and liver cancer. Alizarin has been widely used as a pigment in textile fabrics and paintings. | ||||||||||||||||||||
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1-Hydroxy-2-methylanthraquinone | 1-Hydroxy-2-methylanthraquinone exhibits antimicrobial, antioxidant, pesticidal, and anti-inflammatory activities. | |||||||||||||||||||||
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Tectoquinone | 98.24% | Tectoquinone (2-Methylanthraquinone) is an inhibitor for SARS CoV-2 major protease (SARS CoV-2 Mpro). Tectoquinone exhibits anti-termite and antiviral activities. | ||||||||||||||||||||
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2-Hydroxy-3-methylanthraquinone | 98.67% | 2-Hydroxy-3-methylanthraquinone (compound 1) is a natural compound isolated from a water extract of Hedyotis diffusa WILLD. 2-Hydroxy-3-methylanthraquinone shows inhibitory activity against protein tyrosine kinases v-src and pp60src, and induces growth arrest and apoptosis in the HepG2 cancer cells. | ||||||||||||||||||||
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2-(Hydroxymethyl)anthraquinone | 97.22% | 2-(Hydroxymethyl)anthraquinone is used as a photoremovable protecting group (PRPG) to chemically cage sex pheromone (e.g. (Z)-11-hexadecen-1-ol (sex pheromone of Chilo infuscatellussnellen)). | ||||||||||||||||||||
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1-Hydroxyanthraquinone (Standard) | ≥98% | 1-Hydroxyanthraquinone, a naturally occurring compound with oral activity from some plants like Tabebuia avellanedae, exhibits carcinogenic effect. | ||||||||||||||||||||
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2-Hydroxyanthraquinone | 98.0% | 2-Hydroxyanthraquinone is a product generated by the photochemical oxidation of Anthracene (ANT) (HY-Y0299). 2-Hydroxyanthraquinone induces ferroptosis in cardiomyocytes by depleting GSH and inhibiting GPX4, leading to cardiac developmental malformations. 2-Hydroxyanthraquinone causes damage to the cerebrovascular system and blood-brain barrier in zebrafish by downregulating the Wnt/β-catenin signaling pathway, as well as inducing inflammation and neuronal apoptosis. 2-Hydroxyanthraquinone can be used in studies related to cerebrovascular diseases and cardiotoxicity. | ||||||||||||||||||||
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Anthraquinone-2-carboxylic acid (Standard) | ≥98% | Anthraquinone-2-carboxylic acid (Standard) is the analytical standard of Anthraquinone-2-carboxylic acid (HY-W031757). This product is intended for research and analytical applications. Anthraquinone-2-carboxylic acid is an orally active anthraquinone compound and Antibacterial agent. Anthraquinone-2-carboxylic acid can be isolated from Bajitian. Anthraquinone-2-carboxylic acid inhibits the activation of DPP-IV, COX-2, NF-κB and AP-1. Anthraquinone-2-carboxylic acid blocks IAV-induced activation of the RIG-I/STAT1 pathway, alleviates IAV-mediated weight loss, and protects against lethal IAV infection. Anthraquinone-2-carboxylic acid inhibits the growth of various Staphylococcus strains. It possesses potent anti-inflammatory, immunomodulatory, analgesic and antibacterial activities.\n |
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Benz[g]isoquinoline-5,10-dione | Benz[g]isoquinoline-5,10-dione, an active component isolated from the ethanolic extract of the aerial parts of Mitracarpus scaber, demonstrates notable in vitro inhibitory activity against AIDS-related pathogens, along with significant antibacterial and antifungal properties, as evidenced by the agar well-diffusion assay. | |||||||||||||||||||||
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References
- [1]. Diaz-Munoz G, et al. Anthraquinones: an overview[J]. Studies in natural products chemistry, 2018, 58: 313-338.
- [2]. Yen G C, Duh P D, Chuang D Y. Antioxidant activity of anthraquinones and anthrone[J]. Food chemistry, 2000, 70(4): 437-441.
- [3]. Andersen DO, et al. In vitro virucidal activity of selected anthraquinones and anthraquinone derivatives. Antiviral Res. 1991 Sep;16(2):185-96. [Content Brief]
- [4]. Barnard D L, et al. Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus[J]. Antiviral research, 1992, 17(1): 63-77.
