481-74-3
481-74-3
Chemical Structure
Chrysophanol
Synonym(s): Chrysophanic acid
- CAS No.: 481-74-3
- Formula:C15H10O4
- Molecular Weight:254.24
IUPAC Name: 1,8-dihydroxy-3-methylanthracene-9,10-dione
InChIKey: LQGUBLBATBMXHT-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2O)C(C3=CC(C)=CC(O)=C13)=O
Biological Activity: Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Chrysophanol | 99.66% | Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Chrysophanol (Standard) | ≥98% | Chrysophanol (Standard) is the analytical standard of Chrysophanol. This product is intended for research and analytical applications. Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Emodin (Standard) | 98.84% | Emodin (Standard) is the analytical standard of Emodin. This product is intended for research and analytical applications. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Phomarin | 98.53% | Phomarin is an inhibitor for dihydrofolate reductase (DHFR). Phomarin exhibits activity against Plasmodium parasites and fungi including Mycrobotryum violaceum and Botrytis cinerea. Phomarin can be used for the research of malaria and fungal infections. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Danthron | 99.22% | Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Rhein | 99.56% | Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Physcion (Standard) | ≥98% | Physcion (Standard) is the analytical standard of Physcion. This product is intended for research and analytical applications. Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Aloe emodin | 98.32% | Aloe emodin (Rhabarberone) is a natural hydroxyanthraquinone with antitumor activities. aloe-emodin can bind with mTORC2 and inhibit its kinase activity. Aloe emodin exerts antiproliferation effects and induces cellular apoptosis. Aloe emodin also exhibits antiviral activity that against influenza A virus. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Islandicin | Islandicin is an anthraquinone compound isolated from almonds. It has antibacterial activity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Pachybasin | Pachybasin is a major metabolite from culture broth of endophytic coelomyceteous AFKR-18 fungus. Pachybasin showes antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
8-Methyl Chrysophanol | 8-Methyl Chrysophanol is an anthraquinone isolated from the bark of Senna macranth. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Anthrarufin | 90.0% | Anthrarufin (9,10-Anthracenedione, 1,5-dihydroxy-_) is an anthraquinone compound that has an inhibitory effect on the activity of the uterine mucosa during pregnancy. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
