Islandicin
Islandicin is an anthraquinone compound isolated from almonds. It has antibacterial activity.
For research use only. We do not sell to patients.
- CAS No.: 476-56-2
- Formula: C15H10O5
- Molecular Weight:270.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Calu-1 | IC50 |
>100 μM
Compound: 8
|
Inhibition of human Calu1 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human Calu1 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
|
[PMID: 11374975] |
| Calu-3 | IC50 |
>50 μM
Compound: 6
|
Cytotoxicity against human Calu3 cells after 96 hrs by Cell Titer Glo assay
Cytotoxicity against human Calu3 cells after 96 hrs by Cell Titer Glo assay
|
[PMID: 23057874] |
| HeLa | IC50 |
>100 μM
Compound: 8
|
Inhibition of human HeLa cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human HeLa cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
|
[PMID: 11374975] |
| K562 | IC50 |
>100 μM
Compound: 8
|
Inhibition of human K562 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human K562 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
|
[PMID: 11374975] |
| Raji | IC50 |
>100 μM
Compound: 8
|
Inhibition of human Raji cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human Raji cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
|
[PMID: 11374975] |
| Vero | IC50 |
>100 μM
Compound: 8
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Inhibition of african green monkey Vero cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of african green monkey Vero cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
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[PMID: 11374975] |
| WISH | IC50 |
>100 μM
Compound: 8
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Inhibition of human WISH cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human WISH cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
|
[PMID: 11374975] |
Chemical Information
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CAS No. 476-56-2
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Molecular Weight 270.24
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Formula C15H10O5
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SMILES
O=C1C2=C(C(C3=C(C=C(C)C(O)=C13)O)=O)C(O)=CC=C2
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Structure Classification
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Initial Source
Penicillium islandicum Sopp.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Lin LC, et al. Cytotoxic principles from Ventilago leiocarpa. J Nat Prod. 2001 May;64(5):674-6. doi: 10.1021/np000569d. PMID: 11374975. [Content Brief]
[2]. Stark AA, et al. Mutagenicity and antibacterial activity of mycotoxins produced by Penicillium islandicum Sopp and Penicillium rugulosum. J Environ Pathol Toxicol. 1978 Nov-Dec;2(2):313-24. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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