2. Anti-infection
  3. Bacterial
  4. Islandicin

Islandicin is an anthraquinone compound isolated from almonds. It has antibacterial activity.

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Islandicin

Islandicin Chemical Structure

CAS No. : 476-56-2

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Islandicin Related Antibodies

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Description

Islandicin is an anthraquinone compound isolated from almonds. It has antibacterial activity[1][2].

Cellular Effect
Cell Line Type Value Description References
Calu-1 IC50
> 100 μM
Compound: 8
Inhibition of human Calu1 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human Calu1 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
[PMID: 11374975]
Calu-3 IC50
> 50 μM
Compound: 6
Cytotoxicity against human Calu3 cells after 96 hrs by Cell Titer Glo assay
Cytotoxicity against human Calu3 cells after 96 hrs by Cell Titer Glo assay
[PMID: 23057874]
HeLa IC50
> 100 μM
Compound: 8
Inhibition of human HeLa cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human HeLa cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
[PMID: 11374975]
K562 IC50
> 100 μM
Compound: 8
Inhibition of human K562 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human K562 cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
[PMID: 11374975]
Raji IC50
> 100 μM
Compound: 8
Inhibition of human Raji cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human Raji cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
[PMID: 11374975]
Vero IC50
> 100 μM
Compound: 8
Inhibition of african green monkey Vero cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of african green monkey Vero cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
[PMID: 11374975]
WISH IC50
> 100 μM
Compound: 8
Inhibition of human WISH cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
Inhibition of human WISH cell proliferation assessed as [3H]thymidine incorporation after 3 days by scintillation counting
[PMID: 11374975]
Molecular Weight

270.24

Formula

C15H10O5
CAS No.
SMILES

O=C1C2=C(C(C3=C(C=C(C)C(O)=C13)O)=O)C(O)=CC=C2
Structure Classification
Initial Source

Penicillium islandicum Sopp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Islandicin Related Classifications

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Islandicin476-56-2BacterialInhibitorinhibitorinhibit

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HY-N15488
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