2310262-10-1
Chemical Structure
PDK4-IN-1
- CAS 番号: 2310262-10-1
- Formula:C22H19N3O2
- Molecular Weight:357.41
IUPAC Name: 1-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)anthracene-9,10-dione
InChIKey: RUCYSQLKCYBLDW-UHFFFAOYSA-N
SMILES: O=C1C2=C(C=CC=C2)C(C3=CC=CC(C4=CN(C5CCNCC5)N=C4)=C13)=O
Biological Activity: PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 has antidiabetic, anticancer and anti-allergic activity[1].
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PDK4-IN-1 | 99.34% | PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM. PDK4-IN-1 potently represses cellular transformation and cellular proliferation and induces apoptosis. PDK4-IN-1 has antidiabetic, anticancer and anti-allergic activity. | ||||||||||||||||||||
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Keywords
