359 Results for "

antibody light chain

" in MedChemExpress (MCE) Product Catalog:
Products (359)

359 Results for "antibody light chain" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-P99977

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Mouse IgG1 kappa, Isotype Control is a negative control reagent/isotype control for mouse-derived IgG1κ antibodies. Mouse IgG1 kappa, Isotype Control, by maintaining the same immunoglobulin structure (including isotype, light chain, etc.) as the specific mouse IgG1κ subtype primary antibody, eliminates false positive signals caused by non-specific binding in immunological experiments, thus playing a core role in verifying the specificity of the experiment. Mouse IgG1 kappa, Isotype Control can be applied to immunolocalization experiments in the field of cell biology, such as immunofluorescence staining and immunohistochemistry, assisting in research on protein subcellular localization and cell structure analysis, ensuring the reliability of experimental results .
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5
5 Cited Publications
Cat. No.: HY-P990545
CAS No.: 2065212-40-8
Synonyms: ANX005

Target:  

Complement System

Research Areas:  

Neurological Disease

Tanruprubart (ANX005) is a C1q inhibitor and C1q depleter. Tanruprubart is a human antibody expressed in CHO cells, with huIgG1 heavy chains and huκ light chains, and its predicted molecular weight (MW) is 145 kDa. For the isotype control of Tanruprubart, refer to Human IgG4 kappa, Isotype Control (HY-P99003). The IC50 of Tanruprubart is 346 ng/mL for humans and 259 ng/mL for rats; its EC50 is 3.8 ng/mL for humans, 5.2 ng/mL for rats, and 9.9 ng/mL for mice. Tanruprubart is applicable to the research of Guillain-Barré syndrome and Alzheimer's disease .
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5
5 Cited Publications
Cat. No.: HY-P990679

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) .
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3
3 Cited Publications
Cat. No.: HY-P99978

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Mouse IgG2a kappa, Isotype Control is a negative control reagent/isotype control for mouse-derived IgG2aκ antibodies. Mouse IgG2a kappa, Isotype Control maintains the same immunoglobulin structure (including isotype, light chain, etc.) as the specific mouse IgG2aκ subtype primary antibody, thus eliminating false positive signals caused by non-specific adsorption in immunological experiments and playing a core role in verifying experimental specificity. Mouse IgG2a kappa, Isotype Control can be applied to immunolocalization experiments such as immunofluorescence staining and immunohistochemistry in the field of cell biology, assisting in protein subcellular localization, cell structure analysis, and other research to ensure the reliability of experimental results .
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2
2 Cited Publications
Cat. No.: HY-P990439

Target:  

IFNAR

Research Areas:  

Inflammation/Immunology

The Anti-IFNAR1 Antibody is a humanized antibody expressed in CHO cells, targeting IFNAR1. The Anti-IFNAR1 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 144.92 kDa. The isotype control for the Anti-IFNAR1 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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2
2 Cited Publications
Cat. No.: HY-P990587

Target:  

CD28

Research Areas:  

Inflammation/Immunology

FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.08 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).
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2
2 Cited Publications
Cat. No.: HY-P990672

Target:  

FGFR

Research Areas:  

Inflammation/Immunology

U3-1784 is a humanized antibody expressed in CHO that targets FGFR4/CD334. U3-1784 is equipped with a huIgG1 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for U3-1784 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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1
1 Cited Publications
Cat. No.: HY-K0215

MCE Protein L Agarose, a 4% highly cross-linked agarose reagent coupled with recombinant Protein L, effectively purifies mammalian monoclonal and polyclonal antibodies which have kappa light chain.

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1
1 Cited Publications
Cat. No.: HY-P990571

Target:  

CD19

Research Areas:  

Inflammation/Immunology

Coltuximab is a CHO-expressed humanized antibody that targets CD19. Coltuximab is composed of huIgG1 heavy chains and huκ light chains, with a molecular weight (MW) of 144.70 kDa. The isotype control for Coltuximab can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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1
1 Cited Publications
Cat. No.: HY-P990572

Research Areas:  

Inflammation/Immunology

DCBY02 is a monoclonal antibody targeting CD93 expressed in CHO cells. DCBY02 has a heavy chain of the mlgG type and a light chain of the mkappa type, with a predicted molecular weight (MW) of 150 kDa. The isotype control for DCBY02 can be referenced as Mouse IgG1 kappa, Isotype Control.
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1
1 Cited Publications
Cat. No.: HY-P990675

Target:  

VEGFR

Research Areas:  

Inflammation/Immunology

VGX-100 is a humanized antibody expressed in CHO cells, targeting VEGFC. VGX-100 is composed of huIgG1 heavy chains and huλ light chains, with a predicted molecular weight (MW) of 143.6 kDa. The isotype control for VGX-100 can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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1
1 Cited Publications
Cat. No.: HY-P990319

Target:  

NAMPT

Research Areas:  

Inflammation/Immunology

ALT-100 (Human IgG4) is a humanized antibody expressed in CHO, targeting NAMPT. ALT-100 (Human IgG4) consists of a huIgG1/huIgG4 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. For inflammatory or fibrotic diseases, the isotype control for ALT-100 (Human IgG4) can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P99481
CAS No.: 1608108-91-3
Synonyms: NEOD001

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Birtamimab (NEOD001) is an investigational monoclonal antibody that specifically and selectively target and clear the amyloid. Birtamimab can be used for the research of light chain amyloidosis .
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Cat. No.: HY-P991699
CAS No.: 3035710-69-8
Synonyms: AZD9829 antibody; INT-020

Research Areas:  

Cancer

Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML) . The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990355

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-CD5 Antibody is a human-derived antibody expressed in CHO, targeting CD5. Anti-CD5 Antibody contains huIgG1 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 145.05 kDa.
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Cat. No.: HY-P990480

Target:  

LDLR

Research Areas:  

Inflammation/Immunology

The Anti-oxLDL Antibody is a humanized antibody expressed in CHO cells that targets oxLDL. The Anti-oxLDL Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-oxLDL Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990352
Synonyms: Ona36
Anti-CD36 Antibody is a humanized antibody expressed in CHO that targets CD36. The Anti-CD36 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-CD36 Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990351

Research Areas:  

Inflammation/Immunology

The Anti-CD34 Antibody is a human-derived antibody expressed in CHO, targeting CD34. The Anti-CD34 Antibody contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-CD34 Antibody can be referenced from Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P991705
CAS No.: 2911556-99-3
Synonyms: JJP-1212

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology

Nebaprubart (JJP-1212) is a humanized IgG4κ antibody against FCAR/CD89, and its corresponding isotype control is Human IgG4 kappa, Isotype Control (HY-P99003). Nebaprubart works by blocking a key receptor involved in inflammation .
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Cat. No.: HY-P990405

Target:  

Ephrin Receptor

Research Areas:  

Inflammation/Immunology

The Anti-EphB2 Antibody is a CHO expressed human antibody that targets EphB2. The Anti-EphB2 Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for the Anti-EphB2 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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