1 Result for "

aryl vinyl sulfate (AVS)-containing

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "aryl vinyl sulfate (AVS)-containing" in MCE Product Catalog:

Cat. No.: HY-169231
Target:  

Bcr-Abl

Research Areas:  

Cancer

BCR-ABL-IN-10 (compound B4) is a covalent and aryl vinyl sulfate (AVS)-containing BCR-ABL inhibitor with an IC50 of 43.1 nM for ABL kinase. BCR-ABL-IN-10 forms a covalent and stable adduct with ABL kinase, leading to sustained inhibition of endogenous BCR-ABL activities. BCR-ABL-IN-10 can be used for the study of chronic myeloid leukemia (CML) .
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