BCR-ABL-IN-10

BCR-ABL-IN-10 (compound B4) is a covalent and aryl vinyl sulfate (AVS)-containing BCR-ABL inhibitor with an IC50 of 43.1 nM for ABL kinase. BCR-ABL-IN-10 forms a covalent and stable adduct with ABL kinase, leading to sustained inhibition of endogenous BCR-ABL activities. BCR-ABL-IN-10 can be used for the study of chronic myeloid leukemia (CML).

For research use only. We do not sell to patients.

  • Formula: C24H22N4O5S
  • Molecular Weight:478.52
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Bcr-Abl Isoforms

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100 mg

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