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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
30 Results for "
benzodiazepine derivative
" in MedChemExpress (MCE) Product Catalog:
Products (30)
30 Results for "benzodiazepine derivative" in MCE Product Catalog:
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Cholecystokinin Receptor Ephrin Receptor Interleukin Related VEGFR HIF/HIF Prolyl-Hydroxylase Akt
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Nastorazepide (Z-360) is an orally active 1,5-benzodiazepine derivative and gastrin/CCK-2 receptor antagonist. Nastorazepide inhibits the specific binding of [ 3H]CCK-8 to the human CCK-2 receptor with a Ki value of 0.47 nM. Nastorazepide inhibits IL-1β, ephrin B1, VEGF, and HIF-1alpha, reduces Akt and NR2B phosphorylation. Nastorazepide has antitumor activity against pancreatic cancer. Nastorazepide inhibits colorectal cancer liver metastasis and relieves pain .
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Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors .
Cat. No.: HY-124467
CAS No.: 39080-67-6
Synonyms: Ro 07-4065
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Difludiazepam (Ro 07-4065), a benzodiazepine derivative, is a GABAA receptor ligand with an IC50 of 4.1 nM. Difludiazepam binds to an allosteric site on the GABAA receptor to potentiate the receptor's response to GABA, reducing neuron excitability. Difludiazepam contains halogenated groups at the ortho position of its phenyl ring .
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Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) . Ro15-4513 is a potent ethanol antagonist . Ro15-4513 has anti-anxiety effect . Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-138014
CAS No.: 172986-25-3
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Cinazepam is a partial GABAA receptor agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders .
Cat. No.: HY-W274194
CAS No.: 82408-04-6
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Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical .
Cat. No.: HY-W101415
CAS No.: 698-87-3
Synonyms: Benzylmethylcarbinol
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Cat. No.: HY-101596
CAS No.: 23980-14-5
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Ethyl dirazepate is a agent which is a benzodiazepine derivative. It has anxiolytic and possibly other characteristic benzodiazepine properties.
Cat. No.: HY-169471
CAS No.: 92262-72-1
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4ʹ-Chloro deschloroalprazolam is a benzodiazepine compound and is a derivative of alprazolam .
Cat. No.: HY-101725A
CAS No.: 86630-81-1
Synonyms: Ro 11-3624; Ro 11-3624/001
(R)-Meclonazepam (Ro 11-3624) is an inactive enantiomer of Meclonazepam. Meclonazepam is a benzodiazepine derivative with anti-schistosomiasis activities .
Cat. No.: HY-W399186
CAS No.: 5527-71-9
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Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity .
Cat. No.: HY-W740297
CAS No.: 1189992-73-1
Cat. No.: HY-167650
CAS No.: 34482-99-0
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Fletazepam is a benzodiazepine derivative with sedative, anxiolytic and muscle relaxant effects. Fletazepam can be utilized in neurological research .
Cat. No.: HY-103476R
CAS No.: 91917-65-6
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Ro15-4513 (Standard) is the analytical standard of Ro15-4513. This product is intended for research and analytical applications. Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) . Ro15-4513 is a potent ethanol antagonist . Ro15-4513 has anti-anxiety effect . Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-U00192
CAS No.: 64078-09-7
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CGP11952 is a triazolyl-Benzaphenon resembling the benzodiazepines in its pharmacological action. CGP11952 is an experimental benzodiazepine derivative.
Cat. No.: HY-100264
CAS No.: 28546-58-9
Synonyms: U31920
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Uldazepam is a benzodiazepine derivative and has the potential for anxiety syndrome treatment.
Synonyms: SAS-643
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Doxefazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsan and skeletal muscle relaxant properties.
Cat. No.: HY-167658
CAS No.: 51037-88-8
Synonyms: KC 1956
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Tuclazepam (KC 1956) is a derivative of benzodiazepines that has anti-anxiety and sedative effects .
Cat. No.: HY-U00215
CAS No.: 143943-72-0
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Ro 41-3290 is the desethylated derivative of Ro 41-3696, which is a nonbenzodiazepine partial agonist at the benzodiazepine receptor.
Cat. No.: HY-121877S
CAS No.: 1190015-82-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
