Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
bicyclic peptides
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "bicyclic peptides" in MCE Product Catalog:
Cat. No.: HY-W010922
CAS No.: 162558-25-0
Research Areas:
Cat. No.: HY-P6292
CAS No.: 2724212-01-3
Research Areas:
Cat. No.: HY-P11032
CAS No.: 3106022-48-1
Target:
Research Areas:
Cat. No.: HY-151829
CAS No.: 2616562-74-2
Target:
Research Areas:
Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Cat. No.: HY-178489
Cat. No.: HY-P10775
Target:
Research Areas:
Cat. No.: HY-P10775A
Cat. No.: HY-203876
CAS No.: 2375600-72-7
Target:
Research Areas:
Cat. No.: HY-149872
CAS No.: 3050582-94-7
Target:
Research Areas:
DCA-RMR1 is a cross-linker. DCA-RMR1 elicits facile bicyclization of native peptides via N-terminus Cys-Cys cross-linking. DCA-RMR1 derivatizes RMR1 with 1,3-dichloroacetone (DCA) .
Cat. No.: HY-78985S
CAS No.: 62790-27-6
Synonyms: Trimesic acid-d3
Cat. No.: HY-182805
Target:
Research Areas:
6-Dehydroxy-demethylation-α-Amanitin-OH-PAB-Ala-Val-CO-C2-mal is a conjugate of the ADC drug toxin molecule and the linker, containing a degradable PEG linker and the toxin molecule I-4, a bicyclic peptide derived from amatoxin .
Cat. No.: HY-P11225
CAS No.: 2699627-67-1
Synonyms: MAP-04-02
Cat. No.: HY-P12216
CAS No.: 3115127-25-5
Target:
Research Areas:
Enlicitide northern fragment 4 is a key intermediate obtained via the retrosynthetic disconnection of Enlicitide decanoate (HY-W1126955). Enlicitide northern fragment 4 participates in the protecting-group-free biocatalytic convergent assembly of Enlicitide decanoate, an oral macrocyclic peptide PCSK9 inhibitor. Enlicitide northern fragment 4 can be used for the synthesis of Enlicitide decanoate, thereby supporting research related to hypercholesterolemia .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
