28 Results for "

bilirubin

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "bilirubin" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-N0323
CAS No.: 635-65-4
Bilirubin is a yellow breakdown product of heme catabolism . Bilirubin exhibits antioxidant and antimutagenic effects .
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1 Cited Publications
Cat. No.: HY-135005A
CAS No.: 114-25-0
Purity:  ≥70.0%
Biliverdin, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin can mediate the protective effects of HO-1 in many disease models including IRI and organ transplantation. Biliverdin exhibits anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant properties .
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1 Cited Publications
Cat. No.: HY-135005
CAS No.: 856699-18-8
Purity:  99.3%
Biliverdin hydrochloride, a tetrapyrrolic pigment, is a product of heme catabolism. Heme is broken down into Biliverdin and carbon monoxide and iron by heme oxidase. Biliverdin hydrochloride is then quickly broken down to bilirubin by Biliverdin reductase. Biliverdin hydrochloride is anti-mutagenic, an antioxidant, anti-inflammatory, and immunosuppressant .
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1 Cited Publications
Cat. No.: HY-147041
CAS No.: 1978336-95-6
Purity:  98.87%
Synonyms: GB1211
Target:  

Galectin

Research Areas:  

Inflammation/Immunology Cancer

Selvigaltin (GB1211) is an orally active galectin-3 small molecule inhibitor with an IC50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci) and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (IL6, TGFβ3, SNAI2, collagen). Selvigaltin restores T-cell activity and induces less tumors and metastasis .
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Cat. No.: HY-N8332
CAS No.: 8008-63-7
Synonyms: Ox bile extract
Bile extract (Ox bile extract) is a complex mixture of substances, containing bile acids, cholesterol, and bilirubin. Bile extract has antimicrobial activity and can induce DNA damage and degrade viral and bacterial membranes. Bile extract can be used in bacterial culture media as a selective inhibitor for the isolation and identification of pathogens .
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Cat. No.: HY-150097
Purity:  ≥99.0%
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .
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Cat. No.: HY-N11424
CAS No.: 17459-92-6
Bilirubin diglucuronide is a bilirubin glycoside conjugate with a 1-O-acyl β-D-glucuronide structure. Bilirubin diglucuronide is the major conjugated bilirubin (HY-N0323) and predominant pigment excreted in the bile of adult humans, rats, dogs and cats. Bilirubin diglucuronide is mainly synthesized via UDP-glucuronosyltransferase-mediated transfer of glucuronic acid from UDP-glucuronic acid to bilirubin monoglucuronide, or via enzymatic disproportionation of two moles of bilirubin monoglucuronide (predominantly producing the IXα configuration). In addition, Bilirubin diglucuronide can also be synthesized from bilirubin or its monoglucuronide in a UDP-glucuronic acid-dependent manner. Pretreatment with phenobarbital significantly enhances the formation process of Bilirubin diglucuronide .
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Cat. No.: HY-P2888
CAS No.: 80619-01-8
Synonyms: BOD
Research Areas:  

Metabolic Disease

Bilirubin oxidase (BOD) is an electrocatalyst with oxygen removal activity. Bilirubin oxidase can catalyze the oxidation of bilirubin to biliverdin. Bilirubin oxidase participates in the metabolism of porphyrins and chlorophyll, and acts as a catalyst for oxygen reduction. Bilirubin oxidase can serve as a component of a single-enzyme oxygen removal system for reductase-based voltammetric biosensors .
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Cat. No.: HY-N5092
CAS No.: 2445-83-2
7-Methylcoumarin is a coumarin derivative with potent hepatoprotective and antioxidant properties. 7-Methylcoumarin is a mechanism-based inhibitor for CYP2A6. 7-Methylcoumarin significantly decreases alanine aminotransferase (ALT), aspartate aminotransferase (AST), and serum bilirubin (TB) in rats with CCl4-induced liver damage, whilst restoring total protein (TP) and albumin (TA) levels in serum as well as preventing oxidative stress. 7-Methylcoumarin can decline mitotic activity of A. sativum promeristem .
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Cat. No.: HY-160250
CAS No.: 2097024-37-6
Target:  

Fluorescent Dye UGT

Research Areas:  

Metabolic Disease

UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
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Cat. No.: HY-129834
CAS No.: 68683-34-1
Purity:  ≥95.0%
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Bilirubin Conjugate disodium is a ditaurate derivative of Bilirubin. Bilirubin, a major end product of heme breakdown, is an important constituent of bile .
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Cat. No.: HY-W743522
Bilirubin-d4 (Technical Grade) is the deuterium labeled Bilirubin.
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Cat. No.: HY-125954A
CAS No.: 43195-60-4
Synonyms: UDP-α-D-glucuronic acid ammonium
Uridine diphosphate glucuronic acid ammonium (UDP-α-D-glucuronic acid ammonium) is a glucuronic acid donor. Uridine diphosphate glucuronic acid ammonium transfers its glucuronic acid moiety to acceptor molecules, thereby forming "ether" glucuronides, while being converted into uridine 5'-pyrophosphate. Uridine diphosphate glucuronic acid ammonium serves as a substrate for Arabidopsis UDP-GlcA 4-epimerase 1, and undergoes reversible 4-epimerization to generate UDP-α-D-galacturonic acid .
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Cat. No.: HY-W011787
CAS No.: 74-31-7
Synonyms: N,N′-Diphenyl-p-phenylenediamine
Research Areas:  

Metabolic Disease

DPPD (N,N′-Diphenyl-p-phenylenediamine) is an orally active antioxidant. DPPD also acts as a toxic substance and pregnancy disruptor .
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Cat. No.: HY-46846
CAS No.: 69011-20-7
Styrene-divinylbenzene sulfonated copolymer is a cation exchange resin prepared from sulfonic acid group-containing microporous styrene/divinylbenzene (DVB) copolymer. Styrene-divinylbenzene sulfonated copolymer serves as the core matrix material for most bilirubin adsorbents. It also acts as a hydrophilic cell immobilization carrier, whose porous structure provides an ideal environment for microbial growth and biochemical reactions .
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Cat. No.: HY-145728
CAS No.: 185229-68-9
Synonyms: ISIS-2302
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

Alicaforsen is an oligonucleotide and immunostimulant targeting human ICAM-1 mRNA. Alicaforsen hybridizes to specific sites to reduce the expression level of ICAM-1. Alicaforsen is applicable to relevant research on psoriasis, rheumatoid arthritis and inflammatory bowel disease .
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Cat. No.: HY-P2888A
CAS No.: 80619-01-8
Synonyms: BOD, bacillus cereus
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Bilirubin oxidase, bacillus cereus is a multi-copper oxidase that catalyzes the oxidation of bilirubin into biliverdin, as well as other tetrapyrroles, phenols, and aryl diamines. Bilirubin oxidase, bacillus cereus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, bacillus cereus can be used to develop enzyme-based biosensors .
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Cat. No.: HY-P2888C
Synonyms: BOD, Bacillus pumilus
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Bilirubin oxidase (BOD), Bacillus pumilus is a multicopper oxidase that catalyzes the oxidation of bilirubin to biliverdin, as well as other tetrapyrrole, phenols, and aryl diamines. Bilirubin oxidase, Bacillus pumilus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, Bacillus pumilus can be used to develop enzyme-based biosensors .
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Cat. No.: HY-P2888B
Synonyms: BOD, Magnaporthe oryzae
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Bilirubin oxidase (BOD), Magnaporthe oryza is a multi-copper oxidase that catalyzes the oxidation of bilirubin to biliverdin and reduces molecular oxygen to water. Bilirubin oxidase, Magnaporthe oryzae can participate in the metabolism of porphyrin and chlorophyll, and is widely used in biochemical research as a catalyst for oxygen reduction .
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Cat. No.: HY-W721484
CAS No.: 17095-63-5
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Stercobilinogen is a gut microorganisms' metabolite of bilirubin (HY-N0323). Stercobilinogen can be used for metabolic research .
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