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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
brain homogenates
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "brain homogenates" in MCE Product Catalog:
10
10 Publications Verification
Cat. No.: HY-N0303
CAS No.: 58186-27-9
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Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM) . Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells . Idebenone quickly crosses the blood-brain barrier.
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Synonyms: Ethanedioic acid diammonium monohydrate
Oxalic acid diammonium monohydrate shows antioxidant acyivity and suppresses lipid peroxidation.
Oxalic acid diammonium monohydrate is a pathogenicity factor for sclerotinia sclerotiorum, and suppresses the oxidative burst of the host plant. Oxalic acid diammonium monohydrate exerts acaricidal activity. Oxalic acid can be used for the researches of sclerotinia disease varroatosis and inflammatory diseases .
Cat. No.: HY-W012530
CAS No.: 156-06-9
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Microorganisms Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
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Cat. No.: HY-101185
CAS No.: 1320211-61-7
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T808 is a selective tau protein-targeting ligand. T808 can be used to synthesize [ 18F]-T808, a highly selective tau protein positron emission tomography (PET) tracer. T808 can also be used to synthesize [ 3H]-T808, a marker for in vitro experiments. T808 can be used for the research of alzheimer’s disease .
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CM398 is a highly selective, orally active Sigma-2 receptor ligand with a Ki value of 0.43 nM. CM398 ameliorates age-related macular degeneration. CM398 exerts analgesic effects on visceral pain, inflammatory pain and neuropathic pain. CM398 can be used in research related to age-related macular degeneration, neuropathic pain and inflammatory pain .
Cat. No.: HY-P1091
CAS No.: 1314035-51-2
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Cat. No.: HY-P1090
CAS No.: 568588-77-2
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Cat. No.: HY-W012530R
CAS No.: 156-06-9
Cat. No.: HY-W016203
CAS No.: 114-76-1
Synonyms: Sodium phenylpyruvate
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Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .
Cat. No.: HY-W041831
CAS No.: 1113-38-8
Synonyms: Ethanedioic acid ammonium
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Oxalic acid (Ethanedioic acid) ammonium is a dicarboxylic acid. Oxalic acid ammonium is widely found in various plants. Oxalic acid ammonium has antioxidant activity and can inhibit lipid peroxidation. Oxalic acid ammonium is a pathogenic factor of Sclerotinia sclerotiorum and can inhibit the oxidative burst of host plants. Oxalic acid ammonium has acaricidal activity. Oxalic acid ammonium can be used for related research on Sclerotinia sclerotiorum disease, Varroa mite disease and inflammatory diseases .
Synonyms: (±)20-HDoHE
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Cat. No.: HY-W777283
CAS No.: 1189907-75-2
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THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe .
Cat. No.: HY-117236
CAS No.: 443989-01-3
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GSI-136 is an inhibitor of γ-secretase with an IC50 of 3 nM. GSI-136 can lead to a dose-dependent reduction of Aβ40 levels in diethylamine-extracted brain homogenates of C57BL/6 mice. GSI-136 can be studied in medicinal chemistry and Alzheimer's disease research .
Cat. No.: HY-N0303R
CAS No.: 58186-27-9
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Idebenone (Standard) is the analytical standard of Idebenone. This product is intended for research and analytical applications. Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM) . Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells . Idebenone quickly crosses the blood-brain barrier.
Cat. No.: HY-101181
CAS No.: 1374107-46-6
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THK-5105, an arylquinoline derivative, displays high binding affinity to tau fibrils. THK-5105 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5105 has the potential to act as a tau imaging PET probe .
Cat. No.: HY-114651
CAS No.: 155233-15-1
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Cat. No.: HY-100998
CAS No.: 96316-00-6
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Metaphit is a specific PCPantagonist and site-directed acylating agent of the [3H]phencyclidine binding site in rat brain homogenates . Metaphit prevents PCP-induced locomotor behavior through presynaptic mechanisms .
Cat. No.: HY-N15282
CAS No.: 128341-11-7
Category:
Flavonols Flavonoids Plants Moraceae Broussonetia papyrifera (Linnaeus) L'Heritier ex Ventenat
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
