568588-77-2
Chemical Structure
Hemopressin(rat)
- CAS No.: 568588-77-2
- Formula:C53H77N13O12
- Molecular Weight:1088.26
IUPAC Name: L-prolyl-L-valyl-L-asparaginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-leucyl-L-seryl-L-histidine
InChIKey: DUTLYPZZJJBEAJ-QISMNGAHSA-N
SMILES: OC([C@H](CC1=CN=CN1)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@@H]2CCCN2)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O
Biological Activity: Hemopressin(rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) exerts antinociceptive action in inflammatory pain models[1][2].
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Hemopressin(rat) | 99.14% | Hemopressin(rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) exerts antinociceptive action in inflammatory pain models. | ||||||||||||||||||||
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- [1]. Camila Squarzoni Dale, et al. Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin. em Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:105-6. [Content Brief]
- [2]. Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31. [Content Brief]
Keywords
