Hemopressin(rat)
Based on 1 Customer Validation
Hemopressin(rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin(rat) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin(rat) exerts antinociceptive action in inflammatory pain models.
For research use only. We do not sell to patients.
- Purity: 99.14%
- CAS No.: 568588-77-2
- Formula: C53H77N13O12
- Molecular Weight:1088.26
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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GPCR/G Protein Compound Library
HY-L006
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Neuronal Signaling Compound Library
HY-L013
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Orally Active Compound Library
HY-L061
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Anti-Obesity Compound Library
HY-L087
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Peptide Library
HY-L105
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Pain-Related Compound Library
HY-L139
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Membrane Protein-targeted Compound Library
HY-L149
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Membrane Receptor-targeted Compound Library
HY-L150
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Highly Selective Inhibitors Library
HY-L158
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Bioactive Compound Library Max
HY-L181
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Peptide Compound Library
HY-L105S
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Lactylation Compound Library
HY-L249
Biological Activity
Oral administration of Hemopressin(rat) inhibits mechanical hyperalgesia of CCI-rats up to 6h. Hemopressin(rat) treatment also decreases Egr-1 immunoreactivity (Egr-1Ir) in the superficial layer of the dorsal horn of the spinal cord of CCI rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 568588-77-2
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Appearance Solid
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Molecular Weight 1088.26
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Formula C53H77N13O12
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Color White to off-white
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Sequence
Pro-Val-Asn-Phe-Lys-Phe-Leu-Ser-His
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Sequence Shortening
PVNFKFLSH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (91.89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Camila Squarzoni Dale, et al. Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin. em Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:105-6. [Content Brief]
[2]. Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9189 mL | 4.5945 mL | 9.1890 mL | 22.9725 mL |
| 5 mM | 0.1838 mL | 0.9189 mL | 1.8378 mL | 4.5945 mL | |
| 10 mM | 0.0919 mL | 0.4594 mL | 0.9189 mL | 2.2972 mL | |
| 15 mM | 0.0613 mL | 0.3063 mL | 0.6126 mL | 1.5315 mL | |
| 20 mM | 0.0459 mL | 0.2297 mL | 0.4594 mL | 1.1486 mL | |
| 25 mM | 0.0368 mL | 0.1838 mL | 0.3676 mL | 0.9189 mL | |
| 30 mM | 0.0306 mL | 0.1531 mL | 0.3063 mL | 0.7657 mL | |
| 40 mM | 0.0230 mL | 0.1149 mL | 0.2297 mL | 0.5743 mL | |
| 50 mM | 0.0184 mL | 0.0919 mL | 0.1838 mL | 0.4594 mL | |
| 60 mM | 0.0153 mL | 0.0766 mL | 0.1531 mL | 0.3829 mL | |
| 80 mM | 0.0115 mL | 0.0574 mL | 0.1149 mL | 0.2872 mL |
Hemopressin(rat) Related Classifications
HY-P1090 Related Classifications
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