114-76-1
Chemical Structure
Phenylpyruvic acid sodium
Synonym(s): Sodium phenylpyruvate
- CAS No.: 114-76-1
- Formula:C9H7NaO3
- Molecular Weight:186.14
IUPAC Name: sodium 2-oxo-3-phenylpropanoate
InChIKey: MQGYVGKMCRDEAF-UHFFFAOYSA-M
SMILES: O=C(C(CC1=CC=CC=C1)=O)O[Na]
Biological Activity: Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity[1][2].
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Phenylpyruvic acid sodium | 98.24% | Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity. | ||||||||||||||||||||
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Phenylpyruvic acid-d5 sodium | 97.71% | Phenylpyruvic acid-d5 sodium is the deuterium labeled Phenylpyruvic acid sodium. | ||||||||||||||||||||
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- [1]. Valerio F, et al. Improvement of the antifungal activity of lactic acid bacteria by addition to the growth medium of phenylpyruvic acid, a precursor of phenyllactic acid. Int J Food Microbiol. 2016 Apr 2;222:1-7. [Content Brief]
- [2]. Rosa, A. P., et al., (2012). Phenylpyruvic acid decreases glucose-6-phosphate dehydrogenase activity in rat brain. Cellular and molecular neurobiology, 32(7), 1113–1118. [Content Brief]
