1189907-75-2
Chemical Structure
Idebenone-13C,d3
- CAS No.: 1189907-75-2
- Formula:C1813CH27D3O5
- Molecular Weight:342.45
InChIKey: JGPMMRGNQUBGND-JVXUGDAPSA-N
SMILES: O=C(C(CCCCCCCCCCO)=C(C1=O)C)C(OC)=C1O[13C]([2H])([2H])[2H]
Biological Activity: Idebenone-13C,d3 is the deuterium labeled and 13C-labeled Idebenone (HY-N0303). Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM)[1]. Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells[2]. Idebenone quickly crosses the blood-brain barrier.
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Idebenone-13C,d3 | 99.62% | Idebenone-13C,d3 is the deuterium labeled and 13C-labeled Idebenone (HY-N0303). Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier. | ||||||||||||||||||||
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Idebenone (Standard) | 96.98% | Idebenone (Standard) is the analytical standard of Idebenone. This product is intended for research and analytical applications. Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier. | ||||||||||||||||||||
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Idebenone | 99.84% | Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 μM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier. | ||||||||||||||||||||
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-
Similarity Score 0.91
HY-121134Decylubiquinone -
Similarity Score 0.78
HY-187089Idebenone impurity 1 -
Similarity Score 0.76
HY-W5101595-O-Methylembelin -
Similarity Score 0.75
HY-121931AA863 -
Similarity Score 0.73
HY-175032ATF3-IN-1 -
Similarity Score 0.71
HY-17473Embelin -
Similarity Score 0.71
HY-113449Ubiquinone-1 -
Similarity Score 0.71
HY-118075Coenzyme Q2 -
Similarity Score 0.71
HY-N8213Rapanone -
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