Decylubiquinone
Based on 1 publication(s) in Google Scholar
Decylubiquinone is an analog of ubiquinone (coenzyme Q10). Decylubiquinone blocks reactive oxygen species (ROS) production in response to glutathione depletion and inhibits activation of the mitochondrial permeability transition.
For research use only. We do not sell to patients.
- Purity: 99.67%
- CAS No.: 55486-00-5
- Formula: C19H30O4
- Molecular Weight:322.44
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Decylubiquinone
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Biological Activity
Decylubiquinone (dUb; 10 μm for 6 hours) exerts its effects on ROS by either inhibition of ROS production by cytochrome bc1 or that it scavenged ROS produced[1].
Decylubiquinone inhibits both the dichlorofluorescein (DCF) fluorescence increase resulting from H2O2 treatment and the DCF fluorescence increase resulting after glutathione (GSH) depletion using diethylmaleate mitochondrially generated ROS)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HL60 cells transfected with bcl-2 (bcl-2) (HL60 B cells)
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Concentration:10 μM
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Incubation Time:6 hours
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Result:Attenuated the ROS increase in HL60 (B) cells.
Chemical Information
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CAS No. 55486-00-5
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Appearance Liquid
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Molecular Weight 322.44
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Formula C19H30O4
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Color Yellow to brown
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SMILES
O=C1C(CCCCCCCCCC)=C(C(C(OC)=C1OC)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Publications (1)
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Journal Impact Factor
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Most Recent
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Acta Pharmacol Sin
Ginsenoside (20)S-APPT induces ferroptosis in hepatocellular carcinoma and cholangiocarcinoma by targeting FSP1. [Abstract]2025 Jun 23. PMID: 40550962
Solvent & Solubility
DMSO : 100 mg/mL (310.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1014 mL | 15.5068 mL | 31.0135 mL | 77.5338 mL |
| 5 mM | 0.6203 mL | 3.1014 mL | 6.2027 mL | 15.5068 mL | |
| 10 mM | 0.3101 mL | 1.5507 mL | 3.1014 mL | 7.7534 mL | |
| 15 mM | 0.2068 mL | 1.0338 mL | 2.0676 mL | 5.1689 mL | |
| 20 mM | 0.1551 mL | 0.7753 mL | 1.5507 mL | 3.8767 mL | |
| 25 mM | 0.1241 mL | 0.6203 mL | 1.2405 mL | 3.1014 mL | |
| 30 mM | 0.1034 mL | 0.5169 mL | 1.0338 mL | 2.5845 mL | |
| 40 mM | 0.0775 mL | 0.3877 mL | 0.7753 mL | 1.9383 mL | |
| 50 mM | 0.0620 mL | 0.3101 mL | 0.6203 mL | 1.5507 mL | |
| 60 mM | 0.0517 mL | 0.2584 mL | 0.5169 mL | 1.2922 mL | |
| 80 mM | 0.0388 mL | 0.1938 mL | 0.3877 mL | 0.9692 mL | |
| 100 mM | 0.0310 mL | 0.1551 mL | 0.3101 mL | 0.7753 mL |
Decylubiquinone Related Classifications
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