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GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-156498
    RMC-7977
    10+ Cited Publications

    		 Ras ERK Raf Ribosomal S6 Kinase (RSK) AMPK Apoptosis PARP Cancer
    RMC-7977 is an orally active triple-complex RAS inhibitor that can simultaneously bind to cyclophilin A (CYPA) (Kd = 195 nM) and KRAS (G12V) (Kd = 292 μM). It exhibits broad-spectrum inhibitory activity against KRAS, NRAS, and HRAS proteins and their various wild-type and mutant variants. RMC-7977 induces apoptosis by inhibiting the phosphorylation of ERK, CRAF, and RSK, as well as increasing PARP cleavage. This leads to tumor regression, reduces resistance in KRAS G12C cancer models, and demonstrates good tolerability across various RAS cancer models .
    RMC-7977
  • HY-P1222
    LL-37, human
    5+ Cited Publications

    		 Bacterial Infection
    LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing .
    LL-37, human
  • HY-17373
    Posaconazole
    10+ Cited Publications

    SCH 56592

    		 Fungal Parasite Infection Cancer
    Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
    Posaconazole
  • HY-16980A
    Eravacycline dihydrochloride
    25+ Cited Publications

    TP-434 dihydrochloride; TP-434-046

    		 Beta-lactamase Bacterial Infection
    Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent.
    Eravacycline dihydrochloride
  • HY-B1923
    Piperacillin
    10+ Cited Publications

    Pipracil

    		 Antibiotic Bacterial Beta-lactamase Penicillin-binding protein (PBP) Infection Cancer
    Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
    Piperacillin
  • HY-B0210
    Cefoperazone
    5+ Cited Publications

    		 Bacterial Antibiotic Infection
    Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .
    Cefoperazone
  • HY-W017162
    DL-3-Phenyllactic acid
    2 Publications Verification

    		 Endogenous Metabolite Bacterial Infection
    DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.
    DL-3-Phenyllactic acid
  • HY-B1729
    Phenoxyethanol

    		Environmental Pollutants Bacterial Fungal Oxidative Phosphorylation Infection
    Phenoxyethanol has a broad spectrum of antimicrobial agent. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al .
    Phenoxyethanol
  • HY-B0849
    Azoxystrobin
    3 Publications Verification

    		 Environmental Pollutants Reactive Oxygen Species (ROS) Fungal Apoptosis Bacterial Phosphatase Infection
    Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis .
    Azoxystrobin
  • HY-P1222A
    LL-37, human TFA
    5+ Cited Publications

    		 Bacterial Infection
    LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing .
    LL-37, human TFA
  • HY-B0210A
    Cefoperazone sodium salt
    5+ Cited Publications

    CP 52640-2

    		 Bacterial Antibiotic Infection
    Cefoperazone sodium salt (CP 52640-2), a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity .
    Cefoperazone sodium salt
  • HY-133704
    Pyrrolnitrin
    1 Publications Verification

    		 Bacterial Fungal Antibiotic Infection
    Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria .
    Pyrrolnitrin
  • HY-14865
    Omadacycline
    30+ Cited Publications

    PTK 0796; Amadacycline

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline
  • HY-14814
    Delafloxacin
    5 Publications Verification

    RX-3341; WQ-3034; ABT492

    		 Bacterial Antibiotic Infection
    Delafloxacin (RX-3341; WQ-3034; ABT492) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .
    Delafloxacin
  • HY-101476
    Emodepside
    1 Publications Verification

    Bay 44-4400

    		 Parasite Infection
    Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
    Emodepside
  • HY-12170
    Prinomastat
    4 Publications Verification

    AG3340; KB-R9896

    		 MMP Apoptosis Cancer
    Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat crosses blood-brain barrier. Antitumor avtivity .
    Prinomastat
  • HY-B0847
    Propiconazole
    2 Publications Verification

    		 Environmental Pollutants Reactive Oxygen Species (ROS) Fungal Infection
    Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
    Propiconazole
  • HY-14865B
    Omadacycline tosylate
    30+ Cited Publications

    PTK 0796 tosylate; Amadacycline tosylate

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline tosylate
  • HY-W753375
    Fluindapyr

    		Environmental Pollutants Fungal Succinate Dehydrogenase Infection
    Fluindapyr is a broad-spectrum pyrazolamide chiral fungicide of succinate dehydrogenase inhibitor (SDHIs) with broad bactericidal spectrum and good efficacy. Fluopimomide is effective against M. incognita in vitro and application of fuopimomide shows some growth promotion effect in cucumber .
    Fluindapyr
  • HY-14814A
    Delafloxacin meglumine
    5 Publications Verification

    ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine

    		 Bacterial Antibiotic Infection
    Delafloxacin meglumine (ABT492 meglumine; RX-3341 meglumine; WQ-3034 meglumine) is a broad-spectrum fluoroquinolone antibiotic. Delafloxacin has a broad spectrum of activity that includes drug-resistant Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumonia .
    Delafloxacin meglumine
  • HY-B1790
    Terconazole

    R42470

    		 Fungal Infection
    Terconazole is a broad-spectrum antifungal medication for the treatment of vaginal yeast infection.
    Terconazole
  • HY-108402A
    Cefodizime sodium

    		Penicillin-binding protein (PBP) Bacterial Antibiotic Infection
    Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts .
    Cefodizime sodium
  • HY-114220
    T-2307

    		Fungal Infection
    T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including Candida species (MIC range, 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range, 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range, 0.0156 to 4 μg/mL) .
    T-2307
  • HY-P1222B
    LL-37, human acetate
    5+ Cited Publications

    		 Bacterial Infection Inflammation/Immunology
    LL-37, human acetate is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human acetate could help protect the cornea from infection and modulates wound healing .
    LL-37, human acetate
  • HY-14865C
    Omadacycline hydrochloride
    30+ Cited Publications

    PTK0796 hydrochloride; Amadacycline hydrochloride

    		 Bacterial Antibiotic Infection
    Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections .
    Omadacycline hydrochloride
  • HY-B0833
    Thiamethoxam
    1 Publications Verification

    		 Environmental Pollutants Insecticide Others
    Thiamethoxam is a broad spectrum neonicotinoid insecticide .
    Thiamethoxam
  • HY-A0153A
    Cephapirin sodium

    Cefapirin sodium

    		 Bacterial Antibiotic Infection
    Cephapirin sodium (Cefapirin sodium) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
    Cephapirin sodium
  • HY-13573
    Biapenem
    4 Publications Verification

    CLI 86815; L 627; LJC 10627

    		 Beta-lactamase Bacterial Antibiotic Infection
    Biapenem (CLI 86815; L 627; LJC 10627) a parenteral carbapenem antibacterial agent with a broad spectrum.
    Biapenem
  • HY-106339
    Lymecycline
    1 Publications Verification

    Mucomycin

    		 Bacterial Infection Inflammation/Immunology
    Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property.
    Lymecycline
  • HY-B2072A
    Cephaloridine hydrate

    		Antibiotic Bacterial Infection
    Cephaloridine hydrate is a broad-spectrum antibacterial antibiotic. Cephaloridine has certain dose-related nephrotoxicity .
    Cephaloridine hydrate
  • HY-12170A
    Prinomastat hydrochloride
    4 Publications Verification

    AG3340 hydrochloride; KB-R9896 hydrochloride

    		 MMP Apoptosis Cancer
    Prinomastat hydrochloride (AG3340 hydrochloride) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat hydrochloride inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat hydrochloride can cross blood-brain barrier. Antitumor avtivity .
    Prinomastat hydrochloride
  • HY-151374
    3-IN-PP1

    		PKD Cancer
    3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer .
    3-IN-PP1
  • HY-B1923R
    Piperacillin (Standard)

    Pipracil (Standard)

    		 Bacterial Reference Standards Antibiotic Beta-lactamase Penicillin-binding protein (PBP) Infection Cancer
    Piperacillin (Standard) is the analytical standard of Piperacillin. This product is intended for research and analytical applications. Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam .
    Piperacillin (Standard)
  • HY-W019852
    Flutriafol

    		Environmental Pollutants Fungal Infection
    Flutriafol is a triazole fungicide with broad spectrum fungicidal activity.
    Flutriafol
  • HY-B1166
    Cefamandole nafate

    Cefamandole formate sodium

    		 Bacterial Antibiotic Infection Inflammation/Immunology
    Cefamandole nafate (Cefamandole formate sodium) is a second-generation broad-spectrum cephalosporin antibiotic .
    Cefamandole nafate
  • HY-114750
    Mebendazole-amine

    		Drug Metabolite Infection
    Mebendazole-amine is a metabolite of Mebendazole (HY-17595). Mebendazole is a broad-spectrum benzimidazole anthelmintic .
    Mebendazole-amine
  • HY-N3139
    Ombuin

    		Bacterial Infection
    Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum antibacterial effect with MIC ranges from 125 to 500 μg/mL .
    Ombuin
  • HY-121969
    DDX3-IN-2

    		HIV Infection
    DDX3-IN-2 is an active DEADbox polypeptide 3 (DDX3) inhibitor with an IC50 value of 0.3 μM. DDX3-IN-2 shows a broad spectrum of antiviral activity. DDX3-IN-2 has the potential to overcome HIV resistance .
    DDX3-IN-2
  • HY-16980
    Eravacycline

    TP-434

    		 Beta-lactamase Bacterial Antibiotic Infection
    Eravacycline is a potent and broad-spectrum antibacterial agent.
    Eravacycline
  • HY-A0153
    Cephapirin

    Cefapirin

    		 Antibiotic Bacterial Infection
    Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity .
    Cephapirin
  • HY-B0414
    Fleroxacin
    1 Publications Verification

    RO 23-6240; AM-833

    		 Bacterial Antibiotic Infection
    Fleroxacin (RO 23-6240) is a broad-spectrum antimicrobial fluoroquinolone.
    Fleroxacin
  • HY-137927
    Benapenem

    		Antibiotic Others
    Benapenem is a carbapenem-type agent that belongs to the broad-spectrum β-lactam antibiotic class.
    Benapenem
  • HY-W516735
    Sedaxane

    		Fungal Succinate Dehydrogenase Infection
    Sedaxane is a new broad-spectrum seed treatment fungicide. Sedaxane inhibits fungal respiration by binding to the succinate dehydrogenase complex in fungal mitochondria. Sedaxane has broad-spectrum activity against a variety of seed-borne and soil-borne fungi. Sedaxane can be used in the study of barley loose smut and barley stripe disease .
    Sedaxane
  • HY-161135A
    (rac)-TBAJ-5307

    		Bacterial Infection
    (rac)-TBAJ-5307 is the racemate of TBAJ-5307 (HY-161135). TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation .
    (rac)-TBAJ-5307
  • HY-108402
    Cefodizime

    		Penicillin-binding protein (PBP) Bacterial Antibiotic Infection
    Cefodizime is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime has no renal toxic effect, good tolerance and immune regulation activity, and has the potential for severe infections of the respiratory and urinary tracts .
    Cefodizime
  • HY-B0847R
    Propiconazole (Standard)

    		Reference Standards Fungal Reactive Oxygen Species (ROS) Infection
    Propiconazole (Standard) is the analytical standard of Propiconazole. This product is intended for research and analytical applications. Propiconazole is an orally active N-substituted triazole used as a fungicide. Propiconazole is a mouse liver hepatotoxicant and a hepatocarcinogen that has adverse reproductive and developmental toxicities in experimental animals .
    Propiconazole (Standard)
  • HY-W040149
    Tetramethrin

    		Environmental Pollutants Insecticide Others
    Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests .
    Tetramethrin
  • HY-B2186
    Piperazine adipate

    		Parasite Infection
    Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
    Piperazine adipate
  • HY-106959
    Flurithromycin

    (8S)-8-Fluoroerythromycin A; P-0501A

    		 Antibiotic Bacterial Infection
    Flurithromycin ((8S)-8-Fluoroerythromycin A) is an orally active broad spectrum antibiotic. Flurithromycin can be used in the research of bacterial infections .
    Flurithromycin
  • HY-108402AR
    Cefodizime sodium (Standard)

    		Penicillin-binding protein (PBP) Reference Standards Bacterial Antibiotic Infection
    Cefodizime (sodium) (Standard) is the analytical standard of Cefodizime (sodium). This product is intended for research and analytical applications. Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity. Cefodizime sodium has no renal toxic effect, good tolerance and immune regulation activity, and can be used for the research of severe infections of the respiratory and urinary tracts[1][2].
    Cefodizime sodium (Standard)

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