5 Results for "

butyrolactone lignan

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "butyrolactone lignan" in MCE Product Catalog:

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Cubebin
Cubebin
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Cat. No.: HY-N10423
CAS No.: 18423-69-3
Synonyms: (-)-Cubebin
Category:  

Lignans Piperaceae Piper cubeba L.f. Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Cholinesterase (ChE) Bacterial Fungal Parasite p38 MAPK

Cubebin ((-)-Cubebin), a dibenzyl butyrolactone lignan, is an orally active AChE inhibitor. Cubebin binds to active sites of NF-κB, TNF-α, and TGF-β1 via hydrogen and hydrophobic interactions, obstructing critical residues to inhibit pro-inflammatory or renal fibrosis-related activity. Cubebin enhances p38 MAPK phosphorylation to increase tyrosinase gene expression, stimulating melanogenesis via elevated tyrosinase activity, expression, and mRNA levels. Cubebin reduces oxidative stress via enhanced endogenous antioxidant enzyme activity and inhibited lipid peroxidation, regulates lipid metabolism, improves glycemic control, and exerts renoprotective effects via reduced renal dysfunction markers and improved renal architecture. Cubebin shows antimicrobial activity. Cubebin exerts larvicidal activity against Angiostrongylus cantonensis larvae, with no cytotoxicity toward monkey or human cell lines or Caenorhabditis elegans. Cubebin can be used for the research of diabetic nephropathy, melanoma, colon adenocarcinoma, neuroangiostrongyliasis, Alzheimer’s disease (AD) and depression .
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Cinnamyl acetate
Cinnamyl acetate
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Cat. No.: HY-N7125
CAS No.: 103-54-8
Category:  

Liliaceae Simple Phenylpropanols Other Diseases  Allium sativum Linn. Phenylpropanoids Plants Disease Research Fields

Target:  

Drug Intermediate

Cinnamyl acetate is a phenylpropanoid ester fragrance ingredient that serves as a precursor for the synthesis of Chloramphenicol (HY-B0239) and butyrolactone costunolide, and possesses antioxidant activity. Cinnamyl acetate is used in the food, cosmetics, personal care, and pharmaceutical industries .
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Cinnamyl acetate (Standard)
Cinnamyl acetate (Standard)
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Cat. No.: HY-N7125R
CAS No.: 103-54-8
Category:  

Liliaceae Simple Phenylpropanols  Allium sativum Linn. Phenylpropanoids Plants

Target:  

Reference Standards Drug Intermediate

Cinnamyl acetate (Standard) is the analytical standard of Cinnamyl acetate (HY-N7125). This product is intended for research and analytical applications. Cinnamyl acetate is a phenylpropanoid ester fragrance ingredient that serves as a precursor for the synthesis of Chloramphenicol (HY-B0239) and butyrolactone costunolide, and possesses antioxidant activity. Cinnamyl acetate is used in the food, cosmetics, personal care, and pharmaceutical industries .
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Cinnamyl acetate-13C2
Cinnamyl acetate-13C2
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Cat. No.: HY-N7125S
CAS No.: 1083053-34-2
Target:  

Isotope-Labeled Compounds Drug Intermediate

Research Areas:  

Others

Cinnamyl acetate- 13C2 is the 13C-labeled Cinnamyl acetate (HY-N7125). Cinnamyl acetate is a phenylpropanoid ester fragrance ingredient that serves as a precursor for the synthesis of Chloramphenicol (HY-B0239) and butyrolactone costunolide, and possesses antioxidant activity. Cinnamyl acetate is used in the food, cosmetics, personal care, and pharmaceutical industries .
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Juspurpurin
Juspurpurin
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Cat. No.: HY-N21659
CAS No.: 602331-38-4
Category:  

Acanthaceae Hypoestes purpurea (L.) R. Br. Lignans Phenylpropanoids Plants

Target:  

Drug Intermediate

Juspurpurin is a seco-lignan glycoside found in Justicia purpurea. Acid hydrolysis of juspurpurin cleaves the β‑D‑glucosidic bond to produce the aglycone 1a and glucose .
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