2 Results for "

congenital hyperinsulinism

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "congenital hyperinsulinism" in MCE Product Catalog:

Cat. No.: HY-169249
Synonyms: Z1620764636
Target:  

Potassium Channel

Research Areas:  

Metabolic Disease

Aekatperone is a reversible KATP channel inhibitor, with an IC50 of 9 μM. Aekatperone can be used for the research of congenital hyperinsulinism (CHI) .
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Cat. No.: HY-176745
CAS No.: 292613-04-8
Target:  

VDAC

Research Areas:  

Metabolic Disease Endocrinology

SW016789 is a hypersecretion-inducer targeting VDAC1. SW016789 can induce insulin hypersecretion and Ca 2+ influx in β-cells directly. SW016789 induces a transient endoplasmic reticulum stress response (ER stress), but does not cause beta cell death. SW016789 has reversible and non-apoptotic characteristics. SW016789 can be used for the study of Diabetes mellitus type 2 (T2DM) β-cell dysfunction .
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