5 Results for "

diet-induced obese (DIO) rats

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "diet-induced obese (DIO) rats" in MCE Product Catalog:

Cat. No.: HY-P10745
CAS No.: 2766385-23-1
Synonyms: ZP8396
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Petrelintide can be utilized in diabetes research .
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Cat. No.: HY-P10745A
Synonyms: ZP8396 acetate
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Perelintide (ZP8396) acetate is a dual amylin and calcitonin receptor agonist (DACRA). Perelintide acetate elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction. Perelintide acetate can be utilized in diabetes research .
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Cat. No.: HY-177297
CAS No.: 1067877-83-1
Synonyms: NVP-LCZ960
Target:  

Glucokinase

Research Areas:  

Metabolic Disease

LCZ960 is an orally active glucokinase (GK) activator. LCZ960 stimulates GK activity in hepatocytes in vitro and stimulates glucose uptake in vivo through hepatic GK activation. LCZ960 lowers blood glucose in mice with diet-induced obesity (DIO). LCZ960 maintains normoglycemia and improves glucose tolerance in DIO mice and rats. LCZ960 stimulates glycogen synthase flux and increases hepatic glycogen turnover in rats. LCZ960 induces increased hepatic glycogen recycling. LCZ960 can be used to study high-fat diet-induced obesity and type 2 diabetes .
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Cat. No.: HY-P11044
Research Areas:  

Metabolic Disease

GEP12 is a GLP-1R/Y1-R/Y2-R tri-receptor agonist peptide with an EC50 of 17.3 nM and an IC50 of 19.2 nM for receptor binding. GEP12 may promote glycemic control and weight loss .
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Cat. No.: HY-P11587
Research Areas:  

Metabolic Disease

BGM1812 is a dual agonist of amylin (hAMY3R) (EC50 = 0.627 nM) and CGRP Receptor (hCTR) (EC50 = 2.27 nM). BGM1812 achieves weight loss, increases the proportion of lean body mass, and reduces fat mass in diet-induced obese (DIO) rats. BGM1812 is applicable to research related to obesity .
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