2 Results for "

diet-induced obese rodent models

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "diet-induced obese rodent models" in MCE Product Catalog:

Cat. No.: HY-12443
CAS No.: 1293395-67-1
Purity:  99.56%
Target:  

Casein Kinase

Research Areas:  

Neurological Disease

PF-5006739 is a potent and selective inhibitor of CK1δ/ε with IC50s of 3.9 nM and 17.0 nM, respectively. PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency for CK1δ/ε and high kinome selectivity. PF-5006739 attenuats opioid agent-seeking behavior in a rodent operant reinstatement model in animals in a dose-dependent manner . PF-5006739 improves glucose tolerance in both diet-induced obesity (DIO) and genetic (ob/ob) mice models of obesity .
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Cat. No.: HY-N19725
CAS No.: 51787-31-6
Calonysterone is an orally effective IL-6 inhibitor. Calonysterone reduces the level of the proinflammatory cytokine IL-6. Calonysterone prevents diet-induced obesity. Calonysterone normalizes abnormal plasma adiponectin and leptin concentrations. Calonysterone increases the percentage of total DNA methylation. Calonysterone enhances antioxidant activity. Calonysterone is applicable to obesity-related research .
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