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electrophysiological responses

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By Targets:	Amyloid-β (1) Biochemical Assay Reagents (1) Cholinesterase (ChE) (1) Drug Isomer (1) Endogenous Metabolite (1) Environmental Pollutants (1) Parasite (1) Sex Pheromone (2)
By Research Areas:	Cardiovascular Disease (1) Infection (3) Metabolic Disease (1) Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128454

Dimethyl trisulfide	Environmental Pollutants Biochemical Assay Reagents	Infection Neurological Disease
Dimethyl trisulfide is a cyanide scavenger. Dimethyl trisulfide can be isolated from garlic, onions, broccoli and similar plants. Dimethyl trisulfide converts cyanide into thiocyanate. Dimethyl trisulfide is used by saprophagous insects to locate breeding sites (decaying organic matter), and is also used by deceptive flowers in brood sites to attract such insects. Dimethyl trisulfide induces electrophysiological responses in houseflies .

HY-W073501

trans-Glutaconic acid trans-2-Pentenedioic acid	Drug Isomer Endogenous Metabolite	Cardiovascular Disease Metabolic Disease
trans-Glutaconic acid (trans-2-Pentenedioic acid) is the trans isomer of Glutaconic acid (HY-W073501A). trans-Glutaconic acid is a neurotoxic metabolite. trans-Glutaconic acid induces weak neurotoxicity in cultured cerebral neocortical neurons. trans-Glutaconic acid elicits significant electrophysiological responses in rat neocortical wedge preparations at high concentrations. trans-Glutaconic acid can be used in studies related to glutaric acidemia type 1 .

HY-W004287

Methyl tridecanoate	Amyloid-β Cholinesterase (ChE) Parasite	Infection Neurological Disease
Methyl tridecanoate is a fatty acid methyl ester. Methyl tridecanoate exhibits an IC₅₀ of 3.26 μM and a K_i of 2.30 μM against AsOBP21f in Anopheles sinensis. Methyl tridecanoate induces electroantennographic responses in female Anopheles sinensis. Methyl tridecanoate shows a dose-dependent attractive effect on Anopheles sinensis. Methyl tridecanoate weakly inhibits β-amyloid aggregation and AChE activity. Methyl tridecanoate can be used in the research of malaria and Alzheimer's disease .

HY-W108424

(Z)-11-Tetradecenyl acetate	Sex Pheromone	Others
(Z)-11-Tetradecenyl acetate is a sex pheromone component and attractant for male Euhyponomeutoides albithoracellus. (Z)-11-Tetradecenyl acetate elicits strong, consistent electrophysiological responses in male Euhyponomeutoides albithoracellus antennal receptors. (Z)-11-Tetradecenyl acetate attracts male Euhyponomeutoides albithoracellus when paired with (E)-11-tetradecenyl acetate, with highest attraction at specific E:Z isomer ratios. (Z)-11-Tetradecenyl acetate can be used for the research of sustainable pest control including monitoring and mating disruption .

HY-W673672

4-Oxodecanoic acid 4-Ketocapric acid; 4-ODA	Sex Pheromone	Infection
4-Oxodecanoic acid (4-Ketocapric acid) is a Sex pheromone component. 4-Oxodecanoic acid can be isolated from the sternal glands on the sixth abdominal segment of unmated female Vespa velutina. When mixed with 4-oxooctanoic acid at the natural secretion ratio of 0.78 in female wasps, 4-Oxodecanoic acid exhibits an attractive effect on male Vespa velutina. 4-Oxodecanoic acid can be used in population monitoring and control research on the invasive species Vespa velutina .

Dimethyl trisulfide	Structural Classification Natural Products Microorganisms Liliaceae Classification of Application Fields Other Diseases Plants Endogenous metabolite Disease Research Fields A．Sativam L. var．Viviparum Regel Source Classification	Environmental Pollutants Biochemical Assay Reagents
Dimethyl trisulfide is a cyanide scavenger. Dimethyl trisulfide can be isolated from garlic, onions, broccoli and similar plants. Dimethyl trisulfide converts cyanide into thiocyanate. Dimethyl trisulfide is used by saprophagous insects to locate breeding sites (decaying organic matter), and is also used by deceptive flowers in brood sites to attract such insects. Dimethyl trisulfide induces electrophysiological responses in houseflies .

Methyl tridecanoate	Structural Classification Natural Products other families Plants Source Classification	Amyloid-β Cholinesterase (ChE) Parasite
Methyl tridecanoate is a fatty acid methyl ester. Methyl tridecanoate exhibits an IC₅₀ of 3.26 μM and a K_i of 2.30 μM against AsOBP21f in Anopheles sinensis. Methyl tridecanoate induces electroantennographic responses in female Anopheles sinensis. Methyl tridecanoate shows a dose-dependent attractive effect on Anopheles sinensis. Methyl tridecanoate weakly inhibits β-amyloid aggregation and AChE activity. Methyl tridecanoate can be used in the research of malaria and Alzheimer's disease .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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electrophysiological responses

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