1 Result for "

extracellular domain of BVES

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "extracellular domain of BVES" in MCE Product Catalog:

Cat. No.: HY-P11741
Research Areas:  

Neurological Disease

BV2 is a delivery peptide that binds to BVES, with a Ka of 2.03 μM for the BVES target. BV2 specifically binds to the extracellular domain of BVES, achieving muscle homing and cellular internalization via caveolae-mediated endocytosis. When BV2 is modified on the surface of exosomes by PMO, it enhances dystrophin restoration in the peripheral muscles and myocardium of dystrophin-deficient mice. BV2 is applicable to research related to Duchenne muscular dystrophy and muscle atrophy .
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