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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
farnesyl-protein transferase
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "farnesyl-protein transferase" in MCE Product Catalog:
Cat. No.: HY-W022657
CAS No.: 85391-05-5
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Cat. No.: HY-N2150
CAS No.: 110659-91-1
Cat. No.: HY-118426
CAS No.: 192185-68-5
Synonyms: (Rac)-IND 58359; (Rac)-R115777
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Research Areas:
(Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice .
Cat. No.: HY-126871
CAS No.: 155179-15-0
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Cat. No.: HY-134579
CAS No.: 148796-51-4
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Cat. No.: HY-183421
CAS No.: 146016-64-0
Synonyms: Gliotoxin monoacetate
Research Areas:
Acetylgliotoxin (Gliotoxin monoacetate) is a farnesyltransferase (FTase) inhibitor with an IC50 of 4.4 μM against human targets. Acetylgliotoxin inhibits the growth of fungal, bacterial, and viral pathogens; it binds to free protein thiols and induces ROS production. Acetylgliotoxin increases the survival rate of Caenorhabditis elegans infected with Candida albicans, but exhibits toxicity at higher concentrations. Acetylgliotoxin is applicable to research related to Candida albicans infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
