148796-51-4
148796-51-4
Chemical Structure
Chaetomellic acid A
- CAS No.: 148796-51-4
- Formula:C19H34O4
- Molecular Weight:326.47
IUPAC Name: 2-methyl-3-tetradecylmaleic acid
InChIKey: ULSDRNDLXFVDED-MSUUIHNZSA-N
SMILES: O=C(O)/C(C)=C(CCCCCCCCCCCCCC)\C(O)=O
Biological Activity: Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chaetomellic acid A | Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice. | |||||||||||||||||||||
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References
- [1]. Nogueira A, et al. The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction. Biomed Res Int. 2017;2017:5125980. [Content Brief]
- [2]. Lingham RB, et al. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protein transferase. Appl Microbiol Biotechnol. 1993 Nov;40(2-3):370-4. [Content Brief]
