Chaetomellic acid A
Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice.
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- CAS. Nr.: 148796-51-4
- Formel: C19H34O4
- Molecular Weight:326.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 148796-51-4
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Molecular Weight 326.47
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Formel C19H34O4
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SMILES
O=C(O)/C(C)=C(CCCCCCCCCCCCCC)\C(O)=O
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Structure Classification
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Initial Source
Chaetomella acutiseta
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Nogueira A, et al. The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction. Biomed Res Int. 2017;2017:5125980. [Content Brief]
[2]. Lingham RB, et al. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protein transferase. Appl Microbiol Biotechnol. 1993 Nov;40(2-3):370-4. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Chaetomellic acid A Related Classifications
HY-134579 Related Classifications
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