192185-68-5
Chemical Structure
(Rac)-Tipifarnib
Synonym(s): (Rac)-IND 58359; (Rac)-R115777
- CAS No.: 192185-68-5
- Formula:C27H22Cl2N4O
- Molecular Weight:489.40
IUPAC Name: 6-(amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
InChIKey: PLHJCIYEEKOWNM-UHFFFAOYSA-N
SMILES: O=C1N(C2=C(C(C3=CC=CC(Cl)=C3)=C1)C=C(C=C2)C(N)(C4=CN=CN4C)C5=CC=C(C=C5)Cl)C
Biological Activity: (Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice[1].
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(Rac)-Tipifarnib | (Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice. | |||||||||||||||||||||
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