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Results for "

fibroblast growth factor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FAP (1) FGFR (53) IGF-1R (1) PDGFR (1) VEGFR (4) Apoptosis (2) Bacterial (1) Biochemical Assay Reagents (1) c-Fms (1) c-Met/HGFR (1) Calcium Channel (1) Caspase (1) Connexin (1) Discoidin Domain Receptor (1) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (1) Endogenous Metabolite (7) Environmental Pollutants (1) ERK (5) FAK (1) Fluorescent Dye (1) Glucocorticoid Receptor (2) GLUT (1) HBV (1) Insulin Receptor (1) Isotope-Labeled Compounds (2) Liposome (1) MMP (1) mRNA (27) Phosphatase (2) PROTACs (2) RAR/RXR (1) Reactive Oxygen Species (ROS) (1) Reference Standards (5) RUNX (1) Sirtuin (1) TNF Receptor (1) TNK1 (1) Toll-like Receptor (TLR) (1) Transmembrane Glycoprotein (1) Tyrosinase (1)
By Research Areas:	Cancer (65) Cardiovascular Disease (10) Endocrinology (4) Infection (3) Inflammation/Immunology (10) Metabolic Disease (15) Neurological Disease (14)
Oligonucleotides:	Aptamers (2) Chemokine & Receptors (2) mRNA (27) Antisense Oligonucleotides (2)

102

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

162

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Ferulic acid Maximum Cited Publications 16 Publications Verification Coniferic acid	FGFR Endogenous Metabolite	Infection Neurological Disease Cancer
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

Triamcinolone acetonide 5+ Cited Publications	Glucocorticoid Receptor FGFR	Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
Triamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis .

Fisogatinib 5 Publications Verification BLU-554	FGFR	Cancer
Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC₅₀ of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling .

2,5-Dihydroxybenzoic acid 2 Publications Verification Gentisic acid	Endogenous Metabolite FGFR	Others
2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of **fibroblast growth factors**.

BLU9931 5+ Cited Publications	FGFR	Cancer
BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC₅₀ of 3 nM and a K_d of 6 nM. BLU9931 has significant antitumor activity .

Rogaratinib 5+ Cited Publications BAY1163877	FGFR	Cancer
Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively .

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (natriuretic peptide receptor type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3). Vosoritide can be used in achondroplasia and dwarfism research .

Bemarituzumab	FGFR	Cancer
Bemarituzumab is a humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has antitumor activity against gastric and breast cancer .

FGL peptide	FGFR	Neurological Disease
FGL peptide is a fibroblast growth factor receptor (FGFR) modulator and blood-brain barrier-penetrant. FGL peptide activates NCAM-FGFR and FGFR1 signaling pathways. FGL peptide alters expression of apoptosis, signal transduction and metabolism regulator genes in traumatic brain injury contexts. FGL peptide can be used for the research of traumatic brain injury .

Ferulic acid sodium Maximum Cited Publications 16 Publications Verification Coniferic acid sodium	FGFR Endogenous Metabolite Reactive Oxygen Species (ROS)	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

Fazpilodemab BFKB8488A; RG-7992; RO-7040551	FGFR	Metabolic Disease
Fazpilodemab (BFKB8488A) is a humanized bispecific IgG1 antibody that selectively targets and activates fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD) .

ERK5-IN-2	ERK	Cardiovascular Disease Cancer
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC₅₀s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis .

SUN11602 2 Publications Verification	FGFR	Neurological Disease
SUN11602 is a novel aniline compound with basic fibroblast growth factor-like activity.

Alofanib 4 Publications Verification RPT835	FGFR Apoptosis	Cardiovascular Disease Cancer
Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Anticancer and antiangiogenic activity .

Neridronate	Phosphatase	Metabolic Disease
Neridronate is an aminobisphosphonate. Neridronate induces osteoblast differentiation, enhances alkaline phosphatase activity and mineralized nodule formation. Neridronate inhibits endothelial cell proliferation, fibroblast growth factor-2-induced capillary-like tube formation, and angiogenesis. Neridronate can be used for osteogenesis imperfecta and Paget’s disease of bone .

Ferulic acid (Standard) 1 Publications Verification Coniferic acid (Standard)	Reference Standards FGFR Endogenous Metabolite	Cancer
Ferulic acid (Standard) is the analytical standard of Ferulic acid. This product is intended for research and analytical applications. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside; Feruloyl glucose ester	Drug Metabolite	Others
Ferulic acid acyl-β-D-glucoside (Ferulic acid glucoside) is a metabolite of Ferulic Acid (HY-N0060). Ferulic acid acyl-β-D-glucoside can be isolated from flaxseed extract. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀ values of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

Aprutumab BAY 1179470	FGFR	Cancer
Aprutumab (BAY 1179470) is a fully human fibroblast growth factor receptor 2 (FGFR2)-specific monoclonal antibody . Aprutumab induces FGFR2 endocytosis and degradation in cancer cells expressing FGFR2. Aprutumab serves as the targeted monoclonal antibody component of the antibody-drug conjugate BAY 1187982 (HY-141600) and mediates the endocytosis of the antibody-drug conjugate into FGFR2-positive cells. Aprutumab can be used for the research of FGFR2-positive solid tumors, including studies on gastric cancer and triple-negative breast cancer .

*Brain Derived Basic Fibroblast* Growth Factor (1-24)** FGF basic (1-24)	Bacterial HBV	Infection Inflammation/Immunology
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .

FGFR2-IN-3	FGFR	Cancer
FGFR2-IN-3 is an inhibitor of fibroblast growth factor receptor 2 (FGFR2). FGFR2-IN-3 has good binding properties, forming key interactions and inducing conformational changes in FGFR2. FGFR2-IN-3 can be used for research on tumors .

ZINC12409120	ERK	Metabolic Disease
ZINC12409120 is a high selective ERK inhibitor. ZINC12409120 acts on disrupting FGF23:α-Klotho interaction to inhibit ERK activity with an IC₅₀ of 5.0 μM .

Gunagratinib 1 Publications Verification ICP-192	FGFR	Cancer
Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding. Gunagratinib can be used for the research of cancer . Gunagratinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .

Ficlatuzumab	c-Met/HGFR	Cancer
Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion .

CPL304110	FGFR	Cancer
CPL304110 is a potent, orally active and selective inhibitor of fibroblast growth factor receptors FGFR (1-3), with IC₅₀ values of 0.75 nM, 0.5 nM, and 3.05 nM for FGFR (1-3), respectively .

(rel)-AR234960 1 Publications Verification	ERK	Cardiovascular Disease
(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. (rel)-AR234960 binds to the MAS receptor to activate the downstream ERK1/2 signaling pathway, inducing the expression of *connective tissue growth* factor (CTGF) and its downstream collagen** subtype genes (such as COL1A1, COL3A1). (rel)-AR234960 promotes collagen synthesis in cardiac fibroblasts through the MAS-ERK1/2-CTGF pathway and aggravates extracellular matrix remodeling. (rel)-AR234960's in vitro effect can be blocked by the MAS inverse agonist AR244555 and MEK1 inhibitor. (rel)-AR234960 regulates the expression of cardiac fibrosis-related genes and can be used in the study of heart failure .

2,5-Dihydroxybenzoic acid (Standard) 2 Publications Verification Gentisic acid (Standard)	Reference Standards Endogenous Metabolite FGFR	Others
2,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 2,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 2,5-Dihydroxybenzoic acid is a derivative of benzoic and a powerful inhibitor of **fibroblast growth factors**.

FGFR1/DDR2 inhibitor 1 2 Publications Verification	FGFR Discoidin Domain Receptor	Cancer
FGFR1/DDR2 inhibitor 1 is an orally active inhibitor of fibroblast growth factor receptor 1 (FGFR1) and discoindin domain receptor 2 (DDR2), with IC₅₀ values of 31.1 nM and 3.2 nM, respectively. Antitumor activity .

BR-cpd7	PROTACs FGFR	Cancer
BR-cpd7 is a PROTAC degrader for fibroblast growth factor receptor FGFR1/2 with DC₅₀ of 10 nM. BR-cpd7 arrests cell cycle, inhibits proliferations of FGFR1/2 aberrant activated tumor cells. (Pink: ligand for target protein FGFR-IN-12 (HY-160013); Black: linker; Blue: ligand for E3 ligase Thalidomide-NH-CH2-COOH (HY-131717))

Anti-CD44 Antibody (Hermes-1) 1 Publications Verification	Transmembrane Glycoprotein	Others
Anti-CD44 Antibody (Hermes-1) is a kind of rat IgG2a κ chimeric antibody, targeting to human CD44. Anti-CD44 Antibody (Hermes-1) blocks the binding of hyaluronan to CD44. Anti-CD44 Antibody (Hermes-1) restores (Platelet-derived Growth Factor-BB)-induced β-receptor activation and motility in fibroblasts. Anti-CD44 Antibody (Hermes-1) causes partial loss of the anti-aging effect of hyaluronic .

SU4984	FGFR PDGFR Insulin Receptor	Cancer
SU4984 is a protein tyrosine kinase inhibitor, with an IC₅₀ of 10-20 μM for fibroblast growth factor receptor 1 (FGFR1). SU4984 is also inhibits *platelet-derived growth* factor receptor, and insulin receptor**. SU4984 can be used for the research of cancer .

Sirtuin modulator 8	Sirtuin	Metabolic Disease Inflammation/Immunology
Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases .

Recifercept TA-46; sFGFR3	FGFR	Others
Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia .

Fanregratinib	FGFR	Cancer
Fanregratinib is a fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor .

JK-P3	VEGFR FGFR	Cancer
JK-P3 is a potent and pan VEGFR2 inhibitor, with IC₅₀s of 7.83 μM, 27 μM and 5.18 μM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor kinase activity in vitro. JK-P3 has anti-angiogenic activity .

SUN13837	FGFR	Neurological Disease
SUN13837 is an orally active, blood-brain barrier permeable FGFR modulator and neuroprotective agent. SUN13837 mimics the activity of basic fibroblast growth factor, stimulates intracellular tyrosine phosphorylation of FGFR and signal transduction in neuronal cells, induces neurite outgrowth, and inhibits glutamate-induced neuronal death. SUN13837 can be used in research related to acute cervical spinal cord injury and severe spinal cord injury .

Human FGF2 mRNA	mRNA	Neurological Disease
Human FGF2 mRNA encodes the human fibroblast growth factor 2 (FGF2) protein, a member of the fibroblast growth factor (FGF) family. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth.

Segigratinib 3D185 free base; HH185 free base	FGFR c-Fms	Cancer
Segigratinib is a fibroblast growth factor receptor tyrosine kinase inhibitor, with antineoplastic effect .

Ferulic acid-13C3	Isotope-Labeled Compounds FGFR Endogenous Metabolite	Cancer
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

FGFR-IN-13	FGFR	Cancer
FGFR-IN-13 (compound III-30) is an irreversible covalent fibroblast growth factor receptor (FGFR) inhibitor. FGFR-IN-13 regulates endogenous FGFR1(IC₅₀=0.20±0.02 nM) and FGFR4(IC₅₀=0.40±0.03 nM) mediated signaling pathways by inhibiting the expression of key proteins. FGFR-IN-13 inhibits total-PARP and Bcl-2 protein expressions, and promote Cleaved-PARP and Bax protein expressions in a dose-dependent manner. FGFR-IN-13 has significant antitumor activity and oral activity .

BW710	FGFR	Cancer
BW710 is an orally active fibroblast growth factor receptor 2 (FGFR2) inhibitor. BW710 inhibits the proliferation of BaF3-FGFR2 cells with an IC₅₀ of 2.8 nM. BW710 abolishes FGFR2 enzymatic activity and is selective against other 75 tyrosine kinases including FGFR1, FGFR3, and FGFR4 at 1 μM. BW710 suppresses the FGFR2 signaling and selectively inhibits FGFR2-driven cancer cell proliferation. BW710 displays reasonable pharmacokinetic properties with an oral bioavailability of 29 % in mice .

Sucrosofate potassium Sucrose octasulfate potassium	MMP Biochemical Assay Reagents	Cardiovascular Disease Metabolic Disease
Sucrosofate potassium (Sucrose octasulfate potassium) is a wound healing promoter. Sucrosofate potassium inhibits MMP, promotes angiogenesis and improves microcirculation. Sucrosofate potassium causes mild skin irritation. Sucrosofate potassium can be used to prepare p (MMA-co-AM)/PVA@PSO hydrogels. Sucrosofate potassium is applicable to research related to diabetic wounds .

FGFR-IN-3	FGFR	Neurological Disease
FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research .

FGFR-IN-7	FGFR	Neurological Disease
FGFR-IN-7 (compound 17) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-7 shows neuroprotective activity. FGFR-IN-7 improves brain exposure and reduced risk of phospholidosis. FGFR-IN-7 can be used for neurodegenerative diseases research .

Human FGFRL1 mRNA	mRNA	Cancer
Human FGFRL1 mRNA encodes the human fibroblast growth factor receptor like 1 (FGFRL1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFRL1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Human FGFR2 mRNA	mRNA	Cancer
Human FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Human FGFR1 mRNA	mRNA	Cancer
Human FGFR1 mRNA encodes the human fibroblast growth factor receptor 1 (FGFR1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

Cat. No.	Product Name

HY-L088

Angiogenesis-Related Compound Library

3,431 compounds

Angiogenesis is the physiological process through which new blood vessels are formed from pre-existing vessels. It occurs in various physiological processes e.g. embryonic development, menstrual cycle, exercise and wound healing etc. Angiogenesis is regulated by both endogenous activators and inhibitors. Some key activators of angiogenesis include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, TGF-β, etc. whereas angiogenesis inhibitors are angiostatin, endostatin, interferon, platelet factor 4, etc. The loss of balance between these opposing signals leads to life threatening diseases like cancer, cardiovascular and ischemic diseases etc. which are thus controlled by exogenous angiogenesis activators (for cardiovascular/ischemic disorders) and inhibitors (for cancer).

MCE offers a unique collection of 3,431 compounds with validated angiogenesis targets modulating properties. MCE angiogenesis-related compound library is an effective tool for angiogenesis research and discovery of angiogenesis-related drugs.

HY-L038

Differentiation Inducing Compound Library

2,405 compounds

Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method.

MCE Differentiation Inducing Compound Library contains a unique collection of 2,405 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

Cat. No.	Product Name	Type

HY-D2260

hMSCs-Neu perchlorate	Fluorescent Dyes
hMSCs-Neu perchlorate (Compound 4) is a fluorescent probe that converts hMSCs into neurons in the presence of fibroblast growth factor (FGF). hMSCs-Neu perchlorate may have important applications in neuropathology and neurodegeneration research .

Cat. No.	Product Name	Type

HY-159069

Zymosan (ZM), 95%

Biochemical Assay Reagents

Zymosan (ZM), 95% is a yeast cell wall-derived carbohydrate-rich preparation and immunomodulator. Zymosan (ZM), 95% binds to and activates TLR-2, TLR-4, and Dectin-1 receptor to trigger downstream signaling pathways. Zymosan (ZM), 95% upregulates TLR-2, TLR-4, and TNF-α mRNA expression, increases serum TNF-α levels, and stimulates splenocyte number and viability in mice. Zymosan (ZM), 95% attenuates melanoma growth progression, modulates macrophage marker gene expression, and mediates phagocytosis, ROS generation, and cytokine production. Zymosan (ZM), 95% reduces Connexin 43 protein and mRNA levels, inhibits gap junctional intercellular communication, and induces proinflammatory factor production in human corneal cells. Zymosan (ZM), 95% induces peritoneal inflammation in mice, functions as a drug carrier, and supports fibroblast cell attachment in hydrogel formulations. Zymosan (ZM), 95% can be used for the research of melanoma, tumors, fungal keratitis, ocular surface inflammatory disorders, and peritoneal inflammation .

HY-E70176

N-Deacetylase/N-Sulfotransferase 1 EC:2.8.2.8; NDST1	Biochemical Assay Reagents
N-Deacetylase/N-Sulfotransferase 1 is a sulfotransferase. N-Deacetylase/N-Sulfotransferase 1 modifies heparan sulfate-dependent growth factor and morphogen signalling .

Cat. No.	Product Name	Target	Research Area

HY-P3503

Vosoritide BMN 111	FGFR	Others
Vosoritide (BMN 111) is a modified recombinant CNP (C-type natriuretic peptide) analogue, binds to NPR-B (natriuretic peptide receptor type B) and reduces the activity of FGFR3 (fibroblast growth factor receptor 3). Vosoritide can be used in achondroplasia and dwarfism research .

HY-P3281

FGL peptide	FGFR	Neurological Disease
FGL peptide is a fibroblast growth factor receptor (FGFR) modulator and blood-brain barrier-penetrant. FGL peptide activates NCAM-FGFR and FGFR1 signaling pathways. FGL peptide alters expression of apoptosis, signal transduction and metabolism regulator genes in traumatic brain injury contexts. FGL peptide can be used for the research of traumatic brain injury .

HY-P3601

*Brain Derived Basic Fibroblast* Growth Factor (1-24)** FGF basic (1-24)	Bacterial HBV	Infection Inflammation/Immunology
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research .

HY-P3587

*Brain-Derived Acidic Fibroblast* Growth Factor (1-11)**	Peptides	Inflammation/Immunology
Brain-Derived Acidic Fibroblast Growth Factor (1-11) is a peptide fragment of brain-derived acidic fibroblast growth factor.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99010

Bemarituzumab	FGFR	Cancer
Bemarituzumab is a humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has antitumor activity against gastric and breast cancer .

HY-P99428

Aldafermin NGM282	Inhibitory Antibodies	Metabolic Disease
Aldafermin (NGM282) is an analog of fibroblast growth factor 19. Aldafermin can be used for the research of nonalcoholic steatohepatitis (NASH) .

HY-P99614

Fazpilodemab BFKB8488A; RG-7992; RO-7040551	FGFR	Metabolic Disease
Fazpilodemab (BFKB8488A) is a humanized bispecific IgG1 antibody that selectively targets and activates fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD) .

HY-P99007

Aprutumab BAY 1179470	FGFR	Cancer
Aprutumab (BAY 1179470) is a fully human fibroblast growth factor receptor 2 (FGFR2)-specific monoclonal antibody . Aprutumab induces FGFR2 endocytosis and degradation in cancer cells expressing FGFR2. Aprutumab serves as the targeted monoclonal antibody component of the antibody-drug conjugate BAY 1187982 (HY-141600) and mediates the endocytosis of the antibody-drug conjugate into FGFR2-positive cells. Aprutumab can be used for the research of FGFR2-positive solid tumors, including studies on gastric cancer and triple-negative breast cancer .

HY-P99196

Ficlatuzumab	c-Met/HGFR	Cancer
Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion .

HY-P990859

Anti-CD44 Antibody (Hermes-1) 1 Publications Verification	Transmembrane Glycoprotein	Others
Anti-CD44 Antibody (Hermes-1) is a kind of rat IgG2a κ chimeric antibody, targeting to human CD44. Anti-CD44 Antibody (Hermes-1) blocks the binding of hyaluronan to CD44. Anti-CD44 Antibody (Hermes-1) restores (Platelet-derived Growth Factor-BB)-induced β-receptor activation and motility in fibroblasts. Anti-CD44 Antibody (Hermes-1) causes partial loss of the anti-aging effect of hyaluronic .

HY-P99823

Recifercept TA-46; sFGFR3	FGFR	Others
Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia .

Recombinant Proteins Recommended:

Fibroblast Growth Factor

Species:	Human (112) Rhesus Macaque (5) Rat (7) Mouse (26) Bovine (2) Cynomolgus (3) Sheep (1) Canine (3) Pig (1)
Tag:	SUMO (2) His (100) Strep (5) Tag Free (38) Avi (10) Myc (1) GST (10) B2M (1) Fc (25)
Source:	HEK293 (64) sf9 insect cells (15) CHO (2) Sf9 insect cells (7) P. pastoris (4) E. coli (70)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701238

	FGF basic Protein, Salmon fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Others	E. coli
	FGF basic Protein, Salmon is the recombinant FGF-basic protein, expressed by E. coli, with tag free.

HY-P700287

	FGF-17 Protein, Human fibroblast growth factor 17; FGF-17; FGF17; HH20 Protein, Human; fibroblast growth factor 17	Human	E. coli
	FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. FGF-17 Protein, Human is the recombinant human-derived FGF-17 protein, expressed by E. coli , with tag free.

HY-P71959A

	FGF-12 Protein, Human (181a.a, His) EIEE47; FGF-12; Fgf12; FGF12_HUMAN; FGF12B; FHF-1; FHF1; fibroblast growth factor 12; fibroblast growth factor 12B; fibroblast growth factor FGF 12b; fibroblast growth factor homologous factor 1; Myocyte activating factor; Myocyte-activating factor	Human	E. coli
	FGF-12, vital for nervous system development, positively regulates voltage-gated sodium channels, particularly SCN8A, enhancing neuronal excitability. It achieves this by elevating the voltage dependence of SCN8A fast inactivation. FGF-12 interacts specifically with the C-terminal region of SCN9A. FGF-12 Protein, Human (181a.a, His) is the recombinant human-derived FGF-12 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700630

	FGF2 Protein, Chicken (His) 1 Publications Verification fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Others	E. coli
	FGF2 Protein acts as a ligand for FGFR1-4 and an integrin ligand for FGF2 signaling. It regulates cell survival, division, differentiation, and migration. FGF2 Protein is a strong mitogen and can induce angiogenesis. FGF2 Protein, Chicken (His) is the recombinant FGF2 protein, expressed by E. coli , with C-6*His labeled tag.

HY-P700289

	FGF-1 Protein, Human (154a.a) 2 Publications Verification fibroblast growth factor 1; FGF-1; Acidic fibroblast growth factor; aFGF; Endothelial Cell growth factor; ECGF; Heparin-Binding growth factor 1; HBGF-1; FGF1; FGFA	Human	E. coli
	FGF-1 protein complexly regulates cell survival, division, angiogenesis, differentiation, and migration. As a potent mitogen, it acts as a ligand for FGFR1 and integrins. FGF-1 Protein, Human (154a.a) is the recombinant human-derived FGF-1 protein, expressed by E. coli , with tag free.

HY-P701242

	Heat Stable FGF basic/bFGF Protein, Human 5 Publications Verification fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Human	E. coli
	FGF basic, or bFGF (fibroblast growth factor basic), initiates at an alternative CUG codon, marking a distinctive feature in translational initiation. This alternative start codon plays a pivotal role in regulating the expression and functional properties of FGF basic.Heat Stable FGF basic/bFGF Protein, Human, Human is the recombinant human-derived Heat Stable FGF-basic protein, expressed by E. coli , with tag free.

HY-P700237AF

	Animal-Free FGF-2 Protein, Pig (His) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Pig	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.Animal-Free FGF-2 Protein, Pig (His), consists of 1 amino acids, produced by E.coli with tag free.This product is for cell culture use only.

HY-P700476

	FGF basic/bFGF protein, Bovine (His) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Bovine	E. coli
	FGF2 protein is a multifunctional ligand that can bind to FGFR1, FGFR2, FGFR3 and FGFR4. It is also a key integrin ligand for FGF2 signal transduction and has an important interaction with the integrin ITGAV:ITGB3. FGF2 plays a critical role in cell survival, division, differentiation, and migration, serves as a potent mitogen, and induces angiogenesis. FFGF basic/bFGF protein, Bovine (His)) is the recombinant bovine-derived FGF2 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P705983

	FGF basic/bFGF Protein, Sheep (P. pastoris, His) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor (bFGF); Heparin-binding growth factor 2 (HBGF-2); FGF2	Sheep	P. pastoris

HY-P70600A

	FGF basic/bFGF Protein, Human (K128N) 1 Publications Verification fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2; FGF2; FGFB	Human	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.

HY-P70439

	FGF-2 Protein, Mouse (154a.a) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Mouse	E. coli
	FGF-2 protein is a member of the fibroblast growth factor family, involved in biological processes such as bone healing, cartilage repair, tumor development, and nerve regeneration. FGF-2 is also a mitogen that accelerates cell proliferation. It regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. FGF-2 protein, Mouse (154 a.a.), is a recombinant protein produced in E. coli (Escherichia coli), consisting of 154 amino acids (M1-S154), and is untagged.

HY-P70440

	FGF basic/bFGF Protein, Human (157a.a) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; FGF2; FGFB	Human	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.FGF basic/bFGF Protein, Human (157a.a), consists of 157 amino acids, produced by E.coli with tag free.

HY-P700054AF

	Animal-Free FGF-11 isoform 1 Protein, Human (His) fibroblast growth factor 11; FHF-3; FHF3; fibroblast growth factor homologous factor 3	Human	E. coli
	The FGF-11 isoform 1 protein is thought to play an important role in the development and function of the nervous system. Its presence indicates involvement in complex processes responsible for establishing and maintaining neural structure and activity. Animal-Free FGF-11 isoform 1 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-11 isoform 1 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P700055AF

	Animal-Free FGF-11 isoform 2 Protein, Human (His) fibroblast growth factor 11; FHF-3; FHF3; fibroblast growth factor homologous factor 3	Human	E. coli
	FGF-11 isoform 2 protein is a member of the fibroblast growth factor family, characterized by broad mitotic and cell survival activities, affecting embryonic development, cell growth, morphogenesis, tissue repair, and tumor growth. Its specific function has not yet been determined, but the expression pattern of its mouse homolog suggests a role in nervous system development. Animal-Free FGF-11 isoform 2 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-11 isoform 2 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P700487

	FGF2 Protein, Chicken (N-His, C-Myc) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Others	E. coli
	FGF2 Protein acts as a ligand for FGFR1-4 and an integrin ligand for FGF2 signaling. It regulates cell survival, division, differentiation, and migration. FGF2 Protein is a strong mitogen and can induce angiogenesis. FGF2 Protein, Chicken (N-His, C-Myc) is the recombinant FGF2 protein, expressed by E. coli , with C-Myc, N-10*His labeled tag.

HY-P700479

	FGF basic/bFGF Protein, Human (P. pastoris, N-His) 2 Publications Verification fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Human	P. pastoris
	FGF basic, or bFGF (fibroblast growth factor basic), initiates at an alternative CUG codon, marking a distinctive feature in translational initiation. This alternative start codon plays a pivotal role in regulating the expression and functional properties of FGF basic. FGF basic/bFGF Protein, Human (P. pastoris, N-His) is the recombinant human-derived FGF basic/bFGF protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P700477

	FGF basic/bFGF protein, Bovine (P. pastoris, N-His) fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-Binding growth factor 2; HBGF-2; Fgf2; Fgf-2	Bovine	P. pastoris
	FGF2 protein is a multifunctional ligand that can bind to FGFR1, FGFR2, FGFR3 and FGFR4. It is also a key integrin ligand for FGF2 signal transduction and has an important interaction with the integrin ITGAV:ITGB3. FGF2 plays a critical role in cell survival, division, differentiation, and migration, serves as a potent mitogen, and induces angiogenesis. FGF basic/bFGF protein, Bovine (P. pastoris, N-His) is the recombinant bovine-derived FGF2 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P7382

	KGF/FGF-7 Protein, Human (N-His) rHuKeratinocyte growth factor/FGF-7, His; Keratinocyte growth factor; fibroblast growth factor-7; HBGF-7	Human	E. coli
	KGF/FGF-7 Protein, Human (His) is a polypeptide mitogen that belongs to the family of fibroblast growth factors, binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells. KGF/FGF-7 Protein, Human (His) and its receptor are important for normal wound healing.

HY-P70597

	KGF/FGF-7 Protein, Human 4 Publications Verification fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF	Human	E. coli
	KGF/FGF-7 Protein is an epithelial cell-specific mitogen secreted by normal stromal fibroblasts. KGF/FGF-7 Protein activates plasminogen activator (PA) activity to promote extracellular matrix degradation. KGF/FGF-7 Protein, Human has activities such as promoting the proliferation and differentiation of epithelial cells (such as keratinocytes, thymic epithelial cells), repairing tissue damage (such as intestinal ischemia/reperfusion injury, bone defects), and regulating immune function (such as improving thymus function in aged mice). KGF/FGF-7 Protein, Human is a recombinant KGF/FGF-7 protein expressed by E. coli without a tag.

HY-P70533

	FGF-8b Protein, Human/Mouse 3 Publications Verification fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B	Human;Mouse	E. coli
	FGF-8b Protein, Human/Mouse is the recombinant mouse, human-derived FGF-8b protein, expressed by E. coli, with tag free.

HY-P70597G

	GMP KGF/FGF-7 Protein, Human fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7; KGF	Human	E. coli
	KGF/FGF-7 proteins coordinate embryonic development and regulate basic processes such as cell proliferation and differentiation. Its critical role extends to normal branching morphogenesis. GMP KGF/FGF-7 Protein, Human is the recombinant human-derived KGF/FGF-7 protein, expressed by E. coli , with tag free.

HY-P78878

	KGF-2/FGF-10 Protein, Human (Biotinylated, His-Avi) FGF-10; fibroblast growth factor 10; Keratinocyte growth factor 2	Human	E. coli
	KGF-2/FGF-10 proteins coordinate embryonic development, regulate cell proliferation and differentiation, and are indispensable in branching morphogenesis. This multifunctional protein may aid in wound healing. KGF-2/FGF-10 Protein, Human (Biotinylated, His-Avi) is the recombinant human-derived KGF-2/FGF-10 protein, expressed by E. coli , with N-His, N-Avi labeled tag. The total length of KGF-2/FGF-10 Protein, Human (Biotinylated, His-Avi) is 171 a.a., with molecular weight of ~27 kDa.

HY-P72803

	FGF-13 Protein, Human fibroblast growth factor 13; FGF-13; FHF-2	Human	E. coli
	FGF-13 protein is a microtubule-binding protein that directly binds and stabilizes tubulin and affects microtubule polymerization. It exerts negative regulation on axonal and leading process branches, which are critical for neuronal polarization and migration in the cerebral cortex and hippocampus. FGF-13 Protein, Human is the recombinant human-derived FGF-13 protein, expressed by E. coli , with tag free.

HY-P77365

	FGF-14 Protein, Canine fibroblast growth factor 14; FHF-4; FGF14	Canine	E. coli
	Fibroblast growth factor 14 is a bioactive protein found in the brain and pituitary gland that promotes fibroblast growth and is involved in embryonic development, angiogenesis, tissue repair and other processes. FGF-14 plays a neuroprotective role in in vitro Alzheimer's disease (AD) models by inhibiting MAPK signaling. FGF-14 Protein, Canine is the recombinant canine-derived FGF14 protein, expressed by E. coli , with tag free.

HY-P7342AF

	Animal-Free KGF-2/FGF-10 Protein, Human (His) 1 Publications Verification FGF-10; fibroblast growth factor-10; Keratinocyte growth factor-2	Human	E. coli
	KGF-2/FGF-10 proteins coordinate embryonic development, regulate cell proliferation and differentiation, and are indispensable in branching morphogenesis. This multifunctional protein may aid in wound healing. Animal-Free KGF-2/FGF-10 Protein, Human (His) is the recombinant human-derived animal-FreeKGF-2/FGF-10 protein, expressed by E. coli , with C-His, C-His labeled tag. This product is for cell culture use only.

HY-P700279

	KGF-2/FGF-10 Protein, Human (N-His) 1 Publications Verification rHuFGF-10, His; fibroblast growth factor-10; Keratinocyte growth factor-2	Human	E. coli
	KGF-2/FGF-10 proteins coordinate embryonic development, regulate cell proliferation and differentiation, and are indispensable in branching morphogenesis. This multifunctional protein may aid in wound healing. KGF-2/FGF-10 Protein, Human (N-His) is the recombinant human-derived KGF-2/FGF-10 protein, expressed by E. coli , with N-His labeled tag.

HY-P7047A

	KGF/FGF-7 Protein, Human (CHO) rHuKGF-1/FGF-7; Keratinocyte growth factor; fibroblast growth factor-7; HBGF-7	Human	CHO
	KGF/FGF-7 Protein, Human (CHO) is a polypeptide mitogen that belongs to the family of fibroblast growth factors, binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells. KGF/FGF-7 Protein and its receptor are important for normal wound healing.

HY-P70673

	KGF/FGF-7 Protein, Human (HEK293, His) 1 Publications Verification fibroblast growth factor 7; FGF-7; Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor; FGF7	Human	HEK293
	KGF/FGF-7 proteins coordinate embryonic development and regulate basic processes such as cell proliferation and differentiation. Its critical role extends to normal branching morphogenesis. KGF/FGF-7 Protein, Human (HEK293, His) is the recombinant human-derived KGF/FGF-7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7349A

	FGF-8e Protein, Human (N-His) fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B	Human	E. coli
	FGF-8e Protein, Human is an isoform of FGF-8, an essential factor during embryonic development, involved in the progression of prostate cancer.

HY-P70473

	FGF-21 Protein, Human (His) 4 Publications Verification fibroblast growth factor 21; FGF-21; FGF21	Human	E. coli
	FGF-21 Proteinas influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. FGF-21 Protein, Human (His) is the recombinant human-derived FGF-21 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P700062AF

	Animal-Free FGF-20 Protein, Human (His) 1 Publications Verification fibroblast growth factor 20; FGF20	Human	E. coli
	FGF-20 protein, a homodimer, functions as a neurotrophic factor essential for regulating central nervous system development and function.It interacts with specific receptors, FGFR2 and FGFR4, with heparan sulfate glycosaminoglycans enhancing the binding affinity between fibroblast growth factors (FGFs) and their receptors, serving as coreceptors in this intricate signaling process.Animal-Free FGF-20 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-20 protein, expressed by E.coli , with C-His labeled tag.This product is for cell culture use only.

HY-P70583

	FGF-19 Protein, Human (His) fibroblast growth factor 19; FGF-19; FGF19	Human	E. coli
	FGF-19 protein plays a crucial role in regulating bile acid biosynthesis by inhibiting CYP7A1 expression through positive regulation of JNK and ERK1/2 cascades. It stimulates glucose uptake in adipocytes, dependent on KLB and FGFR4. FGF-19 Protein, Human (His) is the recombinant human-derived FGF-19 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P72195

	FGF-23 Protein, Rat (His) Fgf23fibroblast growth factor 23; FGF-23	Rat	E. coli
	FGF-23 protein is a key regulator of phosphate homeostasis and inhibits renal tubular phosphate transport by reducing SLC34A1 levels. It also modulates vitamin D metabolism, negatively regulates osteoblast differentiation and matrix mineralization, and reduces parathyroid hormone secretion from the parathyroid glands. FGF-23 Protein, Rat (His) is the recombinant rat-derived FGF-23 protein, expressed by E. coli , with N-6*His labeled tag.

HY-P72649

	FGF-4 Protein, Mouse fibroblast growth factor 4; FGF-4; HBGF-4; HST	Mouse	E. coli
	The FGF-4 protein plays a key role in embryonic development and is central to cell proliferation and differentiation. It is essential for the survival of mouse embryos after implantation and is key to normal limb and heart valve development. FGF-4 Protein, Mouse is the recombinant mouse-derived FGF-4 protein, expressed by E. coli , with tag free.

HY-P72653

	FGF-17 Protein, Mouse (His) fibroblast growth factor 17; FGF-17; FGF17	Mouse	E. coli
	The FGF-17 Protein is crucial in regulating embryonic development, functioning as a signaling molecule for inducing and patterning the embryonic brain. It plays an essential role in normal brain development and interacts specifically with FGFR3 and FGFR4 receptors, pivotal in this developmental process. FGF-17 Protein, Mouse (His) is the recombinant mouse-derived FGF-17, expressed by E. coli, with C-6His labeled tag. The total length of FGF-17 Protein, Mouse (His) is 194 a.a.*.

HY-P704167

	FGF-20 Protein, Mouse (His) fibroblast growth factor 20; FGF20; Fgf20	Mouse	E. coli
	FGF-20 Protein, Mouse (His) is the recombinant mouse-derived FGF-20 protein, expressed by E. coli, with N-6*His tag.

HY-P704732

	KGF/FGF-7 Protein, Human (HEK293) rHuKGF-1/FGF-7; Keratinocyte growth factor; fibroblast growth factor-7; HBGF-7	Human	HEK293
	KGF/FGF-7 proteins coordinate embryonic development and regulate basic processes such as cell proliferation and differentiation. Its critical role extends to normal branching morphogenesis. KGF/FGF-7 Protein, Human (HEK293) is the recombinant human-derived KGF/FGF-7 protein, expressed by HEK293, with tag free.

HY-P7012

	FGF-21 Protein, Human 1 Publications Verification rHuFGF-21; fibroblast growth factor-21(FGF-21)	Human	E. coli
	FGF-21 Protein, Human is an atypical member of the ﬁbroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.

HY-P700070AF

	Animal-Free FGF-8b Protein, Human/Mouse (His) fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B	Mouse;Human	E. coli
	Animal-Free FGF-8b Protein, Human/Mouse (His) is the recombinant human-derived animal-FreeFGF-8b protein, expressed by E. coli, with C-His labeled tag. This product is for cell culture use only.

HY-P704367

	FGF-8b Protein, Human/Mouse (HEK293, His) fibroblast growth factor 8; Androgen-induced growth factor; Heparin-binding growth factor 8; AIGF; HBGF-8; FGF-8B	Human	HEK293
	FGF-8b Protein, Human/Mouse (HEK293, His) is the recombinant human-derived FGF-8b protein, expressed by HEK293, with C-His tag.

HY-P700067AF

	Animal-Free FGF-5 Protein, Human (His) fibroblast growth factor 5; Heparin-binding growth factor 5; HBGF-5; Smag-82; FGF5	Human	E. coli
	Animal-Free FGF-5 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-5 protein, expressed by E. coli, with C-His labeled tag. This product is for cell culture use only.

HY-P701232

	KGF-2/FGF-10 Protein, Rat rMuFGF-10; fibroblast growth factor 10; Fgf10	Rat	E. coli
	KGF-2/FGF-10 Protein is vital in regulating embryonic development, crucial for cell proliferation, differentiation, and normal branching morphogenesis. Essential for organ and tissue development, it interacts with FGFR1 and FGFR2, integral to its signaling. The protein may contribute to wound healing and engages with FGFBP1, indicating regulatory interactions within FGF signaling pathways. KGF-2/FGF-10 Protein, Rat is the recombinant rat-derived KGF-2/FGF-10 protein, expressed by E. coli , with tag free.

HY-P7344

	FGF-16 Protein, Human (CHO) rHuFGF-16; FGF-16; fibroblast growth factor-16	Human	CHO
	FGF-16 Protein, Human (CHO) is a polypeptide chain containing 206 amino acids produced in CHO cells. FGF-16 is a heparin binding growth factor, a member of the FGF family.

HY-P72651

	FGF-21 Protein, Mouse (HEK293, His) 2 Publications Verification FGF21; fibroblast growth factor 21; FGF-21	Mouse	HEK293
	FGF-21 Proteinas influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. FGF-21 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGF-21 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72652

	FGF-17 Protein, Human (HEK293, His) 1 Publications Verification fibroblast growth factor 17; FGF-17; FGF17	Human	HEK293
	FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. FGF-17 Protein, Human (HEK293, His) is the recombinant human-derived FGF-17 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P700060AF

	Animal-Free FGF-17 Protein, Human (His) 1 Publications Verification fibroblast growth factor 17; FGF-17; FGF17	Human	E. coli
	FGF-17 Protein plays a crucial role in embryonic development, serving as a signaling molecule for brain induction and patterning. Its presence is vital for normal brain development, emphasizing its significance in shaping embryogenesis intricacies. FGF-17 interacts with FGFR3 and FGFR4, underscoring its involvement in signaling cascades that precisely orchestrate developmental events in the embryonic brain. Animal-Free FGF-17 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-17 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P72650

	FGF-21 Protein, Cynomolgus (HEK293, His) FGF21; fibroblast growth factor 21; FGF-21	Cynomolgus	HEK293
	FGF-21 is a metabolic regulator and a potential anti-diabetic agent. FGF-21 regulates energy balance and glucose and lipid homeostasis through a heterodimeric receptor complex comprising FGFR1 and 尾-klotho. FGF-21 can also signal through FGFR2 and FGFR3. FGF-21 can be used for research of obesity, NASH, NAFLD, and type 2 diabetes mellitus. FGF-21 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FGF-21 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72654

	FGF-12 Protein, Human fibroblast growth factor 12; FGF-12; FHF-1; FGF12B	Human	E. coli
	FGF-12, vital for nervous system development, positively regulates voltage-gated sodium channels, particularly SCN8A, enhancing neuronal excitability. It achieves this by elevating the voltage dependence of SCN8A fast inactivation. FGF-12 interacts specifically with the C-terminal region of SCN9A. FGF-12 Protein, Human is the recombinant human-derived FGF-12 protein, expressed by E. coli , with tag free.

HY-P70440G

	GMP FGF basic/bFGF Protein, Human fibroblast growth factor 2; FGF-2; bFGF; HBGF-2	Human	E. coli
	FGF-2 is a member of the fibroblast family involved in bone healing, cartilage repair, bone repair, and nerve regeneration. FGF-2 is also a mitotic promoter that accelerates cell proliferation. FGF-2 regulates immune processes by specifically targeting tyrosine kinase receptors and activating the FGF/FGFR signaling pathway. For example, FGF-2 is involved in the JAK-STAT signaling pathway to regulate cartilage metabolism and also activates ERK signaling to promote cartilage regeneration. FGF-2 combined with FGFR1/3 promoted degeneration and repair of articular cartilage, respectively. FGF-2 is also a known carcinogen in GBM, which contributes to glioma growth and vascularization.GMP FGF basic/bFGF Protein, Human, consists of 157 amino acids, produced by E.coli with tag free.

HY-P75762

	FGF-21 Protein, Hamster (HEK293, His) FGF21; fibroblast growth factor 21; FGF-21	Others	HEK293
	FGF21 is a liver factor that signals through the FGF21 receptor in the paraventricular nucleus of the hypothalamus to regulate monosaccharide intake and preference for sweets. FGF21 promotes the progression of non-small cell lung cancer by activating the SIRT1/PI3K/AKT signaling pathway. FGF21 plays an important role in embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 Protein, Hamster (HEK293, His) is the recombinant FGF-21 protein, expressed by HEK293 , with C-His labeled tag.

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Host:	Mouse (6) Rabbit (16)
Reactivity:	Human (20) Rat (10) Mouse (13) Monkey (1)
Application:	IHC-P (7) ICC/IF (6) IP (7) WB (21) FC (3) ELISA (5)
Isotype:	IgG (16) IgG1 (1)
Conjugation:	PE (1) Non-conjugated (21) Biotin (6)
Clonality:	Monoclonal (19) Recombinant (12)
Modification:	Unmodified (19)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P81685

	FGF1 Antibody (YA1430) FGF1; FGFA; fibroblast growth factor 1; FGF-1; Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1	WB, IHC-P	Human, Mouse, Rat
	FGF1 Antibody (YA1430) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF1.

HY-P80671

	FGF-2 Antibody (YA442) 1 Publications Verification FGF2; FGFB; fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2	WB, IP, FC, IHC-P	Human, Mouse
	FGF-2 Antibody (YA442) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF-2.

HY-P85160

	FGF-2 Antibody (YA4852) FGF2; FGFB; fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2	WB, IHC-P, ICC/IF, ELISA	Human
	FGF-2 Antibody (YA4852) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FGF-2.

HY-P89404

	FGF-2 Antibody (YA8853) FGF2; FGFB; fibroblast growth factor 2; FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2	WB, ICC/IF, ELISA	Human, Mouse, Rat
	FGF-2 Antibody (YA8853) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FGF-2.

HY-P80733

	KGF Antibody (YA323) Fgf7; fibroblast growth factor 7; HBGF7; Heparin binding growth factor 7; Keratinocyte growth factor	WB	Human, Mouse, Rat
	KGF Antibody (YA323) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KGF.

HY-P80733A

	KGF Antibody (YA323)(PBS only) Fgf7; fibroblast growth factor 7; HBGF7; Heparin binding growth factor 7; Keratinocyte growth factor	WB	Human, Mouse, Rat
	KGF Antibody (YA323) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KGF.

HY-P82927

	FGF19 Antibody (YA2672) FGF19; fibroblast growth factor 19	WB	Human
	FGF19 Antibody (YA2672) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF19.

HY-P83531

	FGF21 Antibody (YA3276) Fgf21; FGFL; fibroblast growth factor 21; PRO10196; UNQ3115	WB, IHC-P	Human, Mouse, Rat
	FGF21 Antibody (YA3276) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF21.

HY-P81843

	FGFR4 Antibody (YA1588) FGFR4; JTK2; TKF; fibroblast growth factor receptor 4; FGFR-4; CD334	WB	Human, Mouse, Rat
	FGFR4 Antibody (YA1588) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGFR4.

HY-P85161

	FGFR4 Antibody (YA4853) FGFR4; JTK2; TKF; fibroblast growth factor receptor 4; FGFR-4; CD antigen CD334	WB, ICC/IF, ELISA	Human
	FGFR4 Antibody (YA4853) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FGFR4.

HY-P85167

	FGFR1 Antibody (YA4859) FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; fibroblast growth factor receptor 1; FGFR-1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD antigen CD331	WB, ELISA	Human
	FGFR1 Antibody (YA4859) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FGFR1.

HY-P86634

	FGFR1 Antibody (YA6326) FGFR1; BFGFR; CEK; FGFBR; FLG; FLT2; HBGFR; fibroblast growth factor receptor 1; FGFR-1; Basic fibroblast growth factor receptor 1; BFGFR; bFGF-R-1; Fms-like tyrosine kinase 2; FLT-2; N-sam; Proto-oncogene c-Fgr; CD antigen CD331	WB, IHC-P, ICC/IF, IP, ELISA	Human
	FGFR1 Antibody (YA6326) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGFR1.

HY-P86877

	FGF18 Antibody (YA6570) FGF 18 antibody; FGF-18 antibody; Fgf18 antibody; FGF18_HUMAN antibody; FGFI antibody; fibroblast growth factor 18 antibody; zFGF5 antibody;	WB	Human, Mouse
	FGF18 Antibody (YA6570) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF18.

HY-P86878

	FGF18 Antibody (YA6571) FGF 18 antibody; FGF-18 antibody; Fgf18 antibody; FGF18_HUMAN antibody; FGFI antibody; fibroblast growth factor 18 antibody; zFGF5 antibody;	WB	Mouse
	FGF18 Antibody (YA6571) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FGF18.

HY-P81655

	FRS2 Antibody (YA1400) fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1	WB, IP	Human
	FRS2 Antibody (YA1400) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FRS2.

HY-P81655A

	FRS2 Antibody (YA1400)(PBS only) fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1	WB, IP	Human
	FRS2 Antibody (YA1400) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FRS2.

HY-P82931

	CD266 Antibody (YA2676) CD266 antigen; FGF inducible 14; fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat
	CD266 Antibody (YA2676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD266.

HY-P82931A

	CD266 Antibody (YA2676)(PBS only) CD266 antigen; FGF inducible 14; fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12A; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat
	CD266 Antibody (YA2676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD266.

HY-P83707M

	Human CD138 Antibody (PE)(YA3444) CD_antigen antibody; CD138 antibody; CD138 antigen antibody; heparan sulfate proteoglycan fibroblast growth factor receptor antibody; SDC antibody; Sdc1 antibody; SDC1_HUMAN antibody; SYND1 antibody; Syndecan 1 antibody; Syndecan antibody; syndecan proteoglycan 1 antibody; Syndecan-1 antibody	FC	Human
	Human CD138 Antibody (PE)(YA3444) is a PE-conjugated, mouse-derived and phycoerythrin (PE) IgG1 monoclonal antibody, targeting to CD138.

HY-P86829

	CXCL1/GRO alpha Antibody (YA6522) C-X-C motif chemokine 1 antibody; Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody; chemokine (C-X-C motif) ligand 1 antibody; CINC-1 antibody; CXCL1 antibody; Cytokine-induced neutrophil chemoattractant 1 antibody; fibroblast secretory protein antibody; Fsp antibody; Gro 1 antibody; Gro A antibody; C-X-C motif chemokine 1 antibody; Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody; chemokine (C-X-C motif) ligand 1 antibody; CINC-1 antibody; CXCL1 antibody; Cytokine-induced neutrophil chemoattractant 1 antibody; fibroblast secretory protein antibody; Fsp antibody; Gro 1 antibody; Gro A antibody; Gro antibody; GRO protein, alpha antibody; GRO-alpha(1-73) antibody; GRO-alpha(6-73) antibody; Gro1 antibody; GRO1 oncogene (melanoma growth stimulating activity, alpha) antibody; GRO1 oncogene (melanoma growth-stimulating activity) antibody; Gro1 oncogene antibody; GROa antibody; GROA_HUMAN antibody; growth-regulated alpha protein antibody; KC antibody; KC chemokine, mouse, homolog of antibody; melanoma growth stimulatory activity alpha antibody; Melanoma growth stimulatory activity antibody; Melanoma growth stimulatory activity, alpha antibody; MGSA alpha antibody; MGSA antibody; MGSA-a antibody; N51 antibody; NAP-3 antibody; NAP3 antibody; Neutrophil-activating protein 3 antibody; Platelet-derived growth factor-inducible protein KC antibody; Scyb 1 antibody; Scyb1 antibody; Secretory protein N51 antibody; Small inducible cytokine subfamily B, member 1 antibody;	WB	Human
	CXCL1/GRO alpha Antibody (YA6522) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CXCL1/GRO alpha.

HY-P86957

	MBD1 Antibody (YA6650) CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; Methyl CpG binding domain protein 1 antibody; Methyl CpG binding domain protein 1 isoform PCM1 antibody; Methyl CpG binding protein MBD1 antibody; CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; Methyl CpG binding domain protein 1 antibody; Methyl CpG binding domain protein 1 isoform PCM1 antibody; Methyl CpG binding protein MBD1 antibody; Methyl CpG binding protein splice variant 1 antibody; Methyl CpG binding protein splice variant 2 antibody; Methyl CpG binding protein splice variant 3 antibody; Methyl CpG binding protein splice variant 4 antibody; Methyl-CpG-binding domain protein 1 antibody; Methyl-CpG-binding protein MBD1 antibody; PCM 1 antibody; PCM1 antibody; Protein containing methyl-CpG-binding domain 1 antibody; Regulator of fibroblast growth factor 2 (FGF 2) transcription antibody; RFT antibody; The regulator of fibroblast growth factor 2(FGF 2) transcription antibody;	WB, ICC/IF, FC	Mouse, Rat
	MBD1 Antibody (YA6650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MBD1.

HY-P85604

	DDX3 Antibody (YA5296) ATP dependent RNA helicase DDX3X; ATP-dependent RNA helicase DDX3X; CAP Rf; DBX; DDX14; DDX3X; DDX3X_HUMAN; DEAD; Asp Glu Ala Asp; box polypeptide 3 X linked; DEAD box; DEAD box protein 3; DEAD box protein 3 X-chromosomal; DEAD box X isoform; DEAD/H; Asp Glu Ala Asp/His; box polypeptide 3; DEAD/H box 3; DEAD/H box 3, X-linked; fibroblast growth factor Inducible 14; Fin14; Helicase like protein 2; Helicase-like protein 2; HLP2; X isoform; X-chromosomal.	WB, IP, ICC/IF	Human, Rat, Mouse, Monkey
	DDX3 Antibody (YA5296) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to DDX3.

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Cat. No.	Product Name		Classification

HY-174702

Human FGF2 mRNA		mRNA Chemokine & Receptors
Human FGF2 mRNA encodes the human fibroblast growth factor 2 (FGF2) protein, a member of the fibroblast growth factor (FGF) family. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth.

HY-174686

Human FGFRL1 mRNA		mRNA
Human FGFRL1 mRNA encodes the human fibroblast growth factor receptor like 1 (FGFRL1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFRL1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

HY-174689

Human FGFR2 mRNA		mRNA
Human FGFR2 mRNA encodes the human fibroblast growth factor receptor 2 (FGFR2) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR2 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

HY-174690

Human FGFR1 mRNA		mRNA
Human FGFR1 mRNA encodes the human fibroblast growth factor receptor 1 (FGFR1) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR1 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

HY-174698

Human FGF23 mRNA		mRNA
Human FGF23 mRNA encodes the human fibroblast growth factor 23 (FGF23) protein, a member of the fibroblast growth factor (FGF) family. FGF23 regulates phosphate homeostasis and transport in the kidney.

HY-174710

Human FGF11 mRNA		mRNA
Human FGF11 mRNA encodes the human fibroblast growth factor 11 (FGF11) protein, a member of the fibroblast growth factor (FGF) family. FGF11 probably involves in nervous system development and function.

HY-174700

Human FGF21 mRNA		mRNA
Human FGF21 mRNA encodes the human fibroblast growth factor 21 (FGF21) protein, a member of the fibroblast growth factor (FGF) family. FGF21 is a secreted endocrine factor that functions as a major metabolic regulator. It stimulates the uptake of glucose in adipose tissue.

HY-174711

Human FGF10 mRNA		mRNA Chemokine & Receptors
Human FGF10 mRNA encodes the human fibroblast growth factor 10 (FGF10) protein, a member of the fibroblast growth factor (FGF) family. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7.

HY-174695

Human FGF5 mRNA		mRNA
Human FGF5 mRNA encodes the human fibroblast growth factor 5 (FGF5) protein, a member of the fibroblast growth factor (FGF) family. FGF5 may play an important role in the regulation of cell proliferation and cell differentiation.

HY-174708

Human FGF13 mRNA		mRNA
Human FGF13 mRNA encodes the human fibroblast growth factor 13 (FGF13) protein, a member of the fibroblast growth factor (FGF) family. FGF13 plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus.

HY-174696

Human FGF4 mRNA		mRNA
Human FGF4 mRNA encodes the human fibroblast growth factor 4 (FGF4) protein, a member of the fibroblast growth factor (FGF) family. FGF4 may play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.

HY-174697

Human FGF3 mRNA		mRNA
Human FGF3 mRNA encodes the human fibroblast growth factor 3 (FGF3) protein, a member of the fibroblast growth factor (FGF) family. FGF3 may play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.

HY-174692

Human FGF8 mRNA		mRNA
Human FGF8 mRNA encodes the human fibroblast growth factor 8 (FGF8) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

HY-174693

Human FGF7 mRNA		mRNA
Human FGF7 mRNA encodes the human fibroblast growth factor 7 (FGF7) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

HY-174691

Human FGF9 mRNA		mRNA
Human FGF9 mRNA encodes the human fibroblast growth factor 9 (FGF9) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.

HY-174694

Human FGF6 mRNA		mRNA
Human FGF6 mRNA encodes the human fibroblast growth factor 6 (FGF6) protein, a member of the fibroblast growth factor (FGF) family. FGF6 may play an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is also required for normal muscle regeneration.

HY-174704

Human FGF18 mRNA		mRNA
Human FGF18 mRNA encodes the human fibroblast growth factor 18 (FGF18) protein, a member of the fibroblast growth factor (FGF) family. FGF18 probably plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. It is also required for normal ossification and bone development.

HY-174705

Human FGF17 mRNA		mRNA
Human FGF17 mRNA encodes the human fibroblast growth factor 17 (FGF17) protein, a member of the fibroblast growth factor (FGF) family. FGF17 probably plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. It is also required for normal brain development.

HY-174706

Human FGF16 mRNA		mRNA
Human FGF16 mRNA encodes the human fibroblast growth factor 16 (FGF16) protein, a member of the fibroblast growth factor (FGF) family. FGF16 probably plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. It is also required for normal cardiomyocyte proliferation and heart development.

HY-174699

Human FGF22 mRNA		mRNA
Human FGF22 mRNA encodes the human fibroblast growth factor 22 (FGF22) protein, a member of the fibroblast growth factor (FGF) family. FGF22 plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. It also can stimulate cell proliferation (in vitro) and may be involved in hair development.

HY-177668A

Umedaptanib pegol sodium RBM-007 sodium		Aptamers
Umedaptanib pegol sodium is an anti-fibroblast growth factor-2 (FGF2) aptamer. It is used for the study of neovascular age-related macular degeneration (nAMD).

HY-177668

Umedaptanib pegol RBM-007		Aptamers
Umedaptanib pegol is an anti-fibroblast growth factor-2 (FGF2) aptamer. It is used for the study of neovascular age-related macular degeneration (nAMD).

HY-174687

Human FGFR4 mRNA		mRNA
Human FGFR4 mRNA encodes the human fibroblast growth factor receptor 4 (FGFR4) protein, a tyrosine kinase and cell surface receptor for fibroblast growth factors. FGFR4 is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis.

HY-159691

IONIS-FGFR4Rx ISIS 463588		Antisense Oligonucleotides
IONIS-FGFR4Rx (ISIS 463588) is an antisense inhibitor of fibroblast growth factor receptor 4 (FGFR4), which is promising for research of renal diseases .

HY-159691A

IONIS-FGFR4Rx sodium ISIS 463588 sodium		Antisense Oligonucleotides
IONIS-FGFR4Rx (ISIS 463588) sodium is an antisense inhibitor of fibroblast growth factor receptor 4 (FGFR4), which is promising for research of renal diseases .

HY-174688

Human FGFR3 mRNA		mRNA
Human FGFR3 mRNA encodes the human fibroblast growth factor receptor 3 (FGFR3) protein, a member of the fibroblast growth factor receptor (FGFR) family. The extracellular portion of FGFR3 protein can interact with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.

HY-174707

Human FGF14 mRNA		mRNA
Human FGF14 mRNA encodes the human fibroblast growth factor 14 (FGF14) protein, a member of the fibroblast growth factor (FGF) family. FGF14 probably involves in nervous system development and function.

HY-174701

Human FGF20 mRNA		mRNA
Human FGF20 mRNA encodes the human fibroblast growth factor 20 (FGF20) protein, a member of the fibroblast growth factor (FGF) family. FGF20 may regulate central nervous system development and function.

HY-174709

Human FGF12 mRNA		mRNA
Human FGF12 mRNA encodes the human fibroblast growth factor 12 (FGF12) protein, a member of the fibroblast growth factor (FGF) family. FGF12 probably involves in nervous system development and function, and the positive regulation of voltage-gated sodium channel activity.

HY-174712

Human FGF1 mRNA		mRNA
Human FGF1 mRNA encodes the human Fibroblast growth factor 1 (FGF1) protein, a member of fibroblast growth factor (FGF) family. FGF1 functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It also acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.

HY-174703

Human FGF19 mRNA		mRNA
Human FGF19 mRNA encodes the human fibroblast growth factor 19 (FGF19) protein, a member of the fibroblast growth factor (FGF) family. FGF19 probably involves in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades.

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fibroblast growth factor

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