76-25-5
Chemical Structure
Triamcinolone acetonide
- CAS No.: 76-25-5
- Formula:C24H31FO6
- Molecular Weight:434.50
IUPAC Name: (6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-6b-fluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10,10-tetramethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
InChIKey: YNDXUCZADRHECN-JNQJZLCISA-N
SMILES: OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C(CC4)=CC(C=C5)=O)C)F)([H])C[C@@]1([H])OC(C)(O2)C)C)=O
Biological Activity: Triamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Triamcinolone acetonide | 99.95% | Triamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis. | ||||||||||||||||||||
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Triamcinolone acetonide (Standard) | 99.79% | Triamcinolone acetonide (Standard) is the analytical standard of Triamcinolone acetonide. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Triamcinolone acetonide-d7 | Triamcinolone acetonide-d7 is the deuterium labeled Triamcinolone acetonide. Triamcinolone acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone. | |||||||||||||||||||||
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Triamcinolone acetonide-13C3 | Triamcinolone acetonide-13C3 is the 13C-labeled Triamcinolone acetonide (HY-B0636). Triamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis. | |||||||||||||||||||||
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Triamcinolone acetonide-d6 | 99.13% | Triamcinolone acetonide-d6 is deuterium labeled Triamcinolone acetonide. | ||||||||||||||||||||
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Triamcinolone acetonide-d7-1 | Triamcinolone acetonide-d7-1 is deuterium labeled Triamcinolone acetonide. | |||||||||||||||||||||
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- [1]. Spandau U H M, et al. Effect of triamcinolone acetonide on proliferation of retinal endothelial cells in vitro and in vivo [J]. British journal of ophthalmology, 2005, 89(6): 745-747.
- [2]. Euppayo T, et al. In vitro effects of triamcinolone acetonide and in combination with hyaluronan on canine normal and spontaneous osteoarthritis articular cartilage [J]. In Vitro Cellular & Developmental Biology-Animal, 2016, 52: 723-735.
- [3]. Siebelt M, et al. Triamcinolone acetonide activates an anti-inflammatory and folate receptor–positive macrophage that prevents osteophytosis in vivo [J]. Arthritis research & therapy, 2015, 17(1): 1-13.
- [4]. Jensen J M, et al. Effects of pimecrolimus compared with triamcinolone acetonide cream on skin barrier structure in atopic dermatitis: a randomized, double-blind, right–left arm trial [J]. Acta Dermato-Venereologica, 2013, 93(5): 515-519.
