8 Results for "

glycan ligands

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "glycan ligands" in MCE Product Catalog:

Cat. No.: HY-158459
Synonyms: A2G2F2(a1-3) glycan
A2G2F2 glycan (A2G2F2(a1-3) glycan) is a Lewis X polysaccharide containing two Lewis X epitopes and is a symmetric N-glycan. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
loading...
    loading...
Cat. No.: HY-158458
Synonyms: A2[3]G1F1(a1-3) glycan
A2[3]G1F1(α-1-3) glycan (A2[3]G1F1(a1-3) glycan) is an asymmetric Lewis X polysaccharide and N-glycan. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
loading...
    loading...
Cat. No.: HY-171172
CAS No.: 2493080-16-1
Target:  

CD22

Research Areas:  

Inflammation/Immunology Cancer

GSC-718 is a CD22 inhibitor with an IC50 of 0.161 μM against mouse CD22. GSC-718 competitively blocks the binding of mouse CD22 to natural glycan ligands, and inhibits the interaction between CD22 and α2,6-sialylated ligands. GSC-718 promotes B cell proliferation and enhances antibody production. GSC-718 can be used in the research of B cell lymphoma and rheumatoid arthritis .
loading...
    loading...
Cat. No.: HY-156230
CAS No.: 2855124-74-0
Research Areas:  

Cancer

Man-GIcNAc-oxazoline is a disaccharide oxazoline based on Manβ1,4GlcNAc. Man-GIcNAc-oxazoline serves as a donor substrate for transglycosylation in endoglycosidase-mediated antibody Fc glycan remodeling. Man-GIcNAc-oxazoline can be modified with azides, PEG-linked azides, fluorescent probes, biotin groups, ligands or prodrugs. Man-GIcNAc-oxazoline can be used for the synthesis of antibody-drug conjugates (ADC). Man-GIcNAc-oxazoline is applicable for cancer research .
loading...
    loading...
Cat. No.: HY-158457
Synonyms: N/A
A2[3]G1 N-glycan (N/A) is a Lewis sugar. SLeX is a ligand for the cell adhesion molecule E-selectin, which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
loading...
    loading...
Cat. No.: HY-158495
Synonyms: A2 N-linked oligosaccharide, 2-AA labelled
A2[3]G1 & A2[6]G1 glycan (G1), 2-AB labeled Lewis sugar. SLeX is a ligand for the cell adhesion molecule E-selectin (E-selectin), which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
loading...
    loading...
Cat. No.: HY-158522
Synonyms: A2[3]G1 & A2[6]G1 N-linked oligosaccharide, 2-AB labelled
A2[3]G1 & A2[6]G1 glycan (G1), 2-AB labeled Lewis sugar. SLeX is a ligand for the cell adhesion molecule E-selectin (E-selectin), which is specifically expressed at sites of inflammatory lesions. Designing SLeX-polysaccharide conjugates to deliver drugs to inflammatory lesions .
loading...
    loading...
Cat. No.: HY-181648
CAS No.: 3059548-99-8
Target:  

Galectin Apoptosis

Research Areas:  

Cancer

Gal-1-IN-1 is a potent and selective human galectin-1 (hGal-1) inhibitor with a Ki of 0.022 μM. Gal-1-IN-1 blocks hGal-1 binding to tumor cells and suppresses human galectin-1-induced pre-apoptosis state. Gal-1-IN-1 reduces hGal-1-expressing cancer cell viability. Gal-1-IN-1 can be used for the research of breast cancer .
loading...
    loading...