2 Results for "

hsa-miR-4477b inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "hsa-miR-4477b inhibitor" in MCE Product Catalog:

Cat. No.: HY-RI01083
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-4477b inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
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Cat. No.: HY-RI01083A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-4477b antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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