4 Results for "

human α4β7 integrin

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "human α4β7 integrin" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P9911
CAS No.: 943609-66-3
Synonyms: Anti-human lymphocyte α4β7 integrin, humanized Antibody; LDP-02; MLN-002

Target:  

Integrin

Research Areas:  

Inflammation/Immunology Cancer

Vedolizumab is a humanized IgG1 monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
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2
2 Cited Publications
Cat. No.: HY-P9984
CAS No.: 1044758-60-2
Synonyms: rhuMAb Beta7; RG7413; PRO145223

Target:  

Integrin

Research Areas:  

Cancer

Etrolizumab (rhuMAb Beta7) is a gut-selective, anti-β7 integrin monoclonal antibody. Etrolizumab is specific targeting of the β7 subunit of α4β7 and αEβ7 integrins with Ki values of 18 nM and 1800 pM for Human α4β7 and Human αEβ7-293, respectively. Etrolizumab can be used in research of inflammatory bowel disease (IBD) .
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Cat. No.: HY-P99184
CAS No.: 1342290-43-0

Target:  

Integrin

Abrilumab is a fully human monoclonal antibody directed against α4β7. Abrilumab selectively binds the α4β7 integrin heterodimer. Abrilumab can be used for the research of inflammatory bowel disease (IBD) .
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Cat. No.: HY-185350
CAS No.: 2640360-68-3
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

α4β7 Integrin-IN-2 is an inhibitor of human α4β7 integrin with an IC50 <5 nM. α4β7 Integrin-IN-2 modulates α4β7 integrin-mediated biological pathways. α4β7 Integrin-IN-2 can be used for the research of inflammatory dieases .
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