88 Results for "

human immunoglobulin G

" in MedChemExpress (MCE) Product Catalog:
Products (88)

88 Results for "human immunoglobulin G" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99550
CAS No.: 2376858-66-9
Synonyms: MEDI-3506

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease .
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1
1 Cited Publications
Cat. No.: HY-P99367
CAS No.: 2484870-90-6
Synonyms: DS-7300a Antibody; MABX-9001A Antibody

Target:  

CD276/B7-H3

Research Areas:  

Inflammation/Immunology Cancer

Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .
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1
1 Cited Publications
Cat. No.: HY-P9920A
CAS No.: 947687-13-0

Target:  

VEGFR

Research Areas:  

Cancer

Ramucirumab (anti-VEGFR) is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab (anti-VEGFR) is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab (anti-VEGFR) is also an angiogenesis inhibitor .
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1
1 Cited Publications
Cat. No.: HY-P70771
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG4; immunoglobulin Heavy Constant Gamma 4; immunoglobulin Heavy Constant Gamma 4 (G4m Marker); Ig Gamma-4 Chain C Region; immunoglobulin Heavy Chain Constant Region Gamma 4
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P73143
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70796
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70705
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGR3A; CD16; Prev. FCGR3; Fc Fragment Of IgG, Low Affinity IIIa, Receptor For (CD16); Prev. FCG3; Fc Of IgG Low Affinity IIIa Receptor Isoform 2; FcgammaRIIIa; Fc Of IgG Low Affinity IIIa Receptor Isoform 1; FcGRIIIA; immunoglobulin G Fc Receptor III; CD16a; Neutrophil-Specific Antigen NA; Low Affinity immunoglobulin Gamma Fc Region Receptor III-A; Fc-Gamma Receptor IIIb (CD16); Fc Fragment Of IgG, Low Affinity IIIa, Receptor (CD16a); Fc Gamma Receptor III-A; Fc Fragment Of IgG Receptor IIIa; Fc-Gamma RIIIa; IgG Fc Receptor III-A; Fc-Gamma RIII; IgG Fc Receptor III-2; FcgammaRIIIA; Fc-Gamma RIII-Alpha; FCRIIIA; CD16a Antigen; FcRIIIa; CD16-II; FcR-10; IGFR3; FcRIII; CD16A; IMD20; Fc Gamma Receptor IIIa; Low Affinity immunoglobulin Gamma Receptor III-A Fc Fragment
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P99955
CAS No.: 2431972-52-8
Synonyms: AMG 451; KHK4083
Rocatinlimab (AMG 451) (KHK4083) is a fully human immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD) .
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Cat. No.: HY-P990047
CAS No.: 2761478-99-1
Synonyms: AMG133 antibody

Research Areas:  

Metabolic Disease

Maridebart (AMG133 antibody) is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody. Maridebart is the antibody portion of Maridebart cafraglutide (HY-164535) and can be used for the synthesis of antibody-drug conjugates (ADC). Maridebart can be used for the reserrch of obesity and type 2 diabetes .
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Cat. No.: HY-P99036
CAS No.: 1296818-77-3

Target:  

Tie

Nesvacumab is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand Angiopoietin-2 (Ang2) with high affinity, but shows no binding to Ang1. Nesvacumab can be used in vascular researches .
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Cat. No.: HY-P99665
CAS No.: 2131038-11-2
Synonyms: LY-3209590

Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes .
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Cat. No.: HY-P99114
CAS No.: 2256084-03-2

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Sugemalimab is a fully human, full length, anti-programmed death ligand 1 (PD-L1) immunoglobulin G4 (IgG4) monoclonal antibody (mAb). Sugemalimab shows anticancer activities and can be used for non-small cell lung cancer research .
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Cat. No.: HY-NP0196
Synonyms: Mouse IgG
Mouse Immunoglobulin G (Mouse IgG) is the most abundant glycoprotein in mouse serum, which bridges innate and adaptive immune responses. A conserved asparagine-297 residue on each heavy chain contains an N-linked glycosylation site. Mouse Immunoglobulin G shares many glycosylation features with human IgG, but contains N-Glycolylneuraminic acid (HY-128965) instead of N-acetylneuraminic acid (HY-I0400). Mouse Immunoglobulin G is widely used as a negative isotype control, immunoassay coating protein and research standard in the life sciences .
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Cat. No.: HY-P99879
CAS No.: 2200269-79-8
Synonyms: Benegrastim; Bineuta; F 627

Target:  

STAT

Research Areas:  

Inflammation/Immunology

Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .
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Cat. No.: HY-D0862
CAS No.: 145551-16-2
DIDNTB is a dye. DIDNTB exhibits chemical sensitivity and specificity toward albumin. DIDNTB is much less affected by other proteins. DIDNTB enables the detection of urinary albumin at concentrations ≥10 mg/L .\n
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Cat. No.: HY-P990032
CAS No.: 2574438-65-4
Synonyms: EOS-448; EOS884448; GSK4428859A
Belrestotug (EOS-448) is an antagonistic anti-TIGIT (VSIG9, VSTM3) human immunoglobulin G1 kappa (hIgG1 kappa) antibody. Belrestotug shows antineoplastic activity. Belrestotug can be used for cancer and immunological research such as colon cancer .
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Cat. No.: HY-P991138
CAS No.: 2981430-39-9
Synonyms: Genakumab; GenSci048; Kinnazumab

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Firsekibart is an immunoglobulin G4-λ2 monoclonal antibody targeting human interleukin 1β (IL-1β). Firsekibart is promising for research of inflammation-related diseases, such as rheumatoid arthritis and inflammatory bowel disease .
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Cat. No.: HY-P990021
CAS No.: 2635404-72-5
Synonyms: TRL1068

Target:  

Bacterial

Research Areas:  

Others

Calpurbatug is an immunoglobulin G1 antibody. Calpurbatug has activity with anti-bacterial DNA-binding protein DNABII family and anti-human monoclonal TRL1068 γ1-chain .
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Cat. No.: HY-P991040
Synonyms: Gamsitabart; M3554 Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

hu14.18 (K322A) is a humanized anti-disialoganglioside GD2 monoclonal antibody that contains fully human amino acid sequences for immunoglobulin G1 heavy and kappa light chains. hu14.18 (K322A) has antibody-dependent cellular cytotoxicity (ADCC). hu14.18 (K322A) can be used for the study of high-risk neuroblastoma .
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Cat. No.: HY-P99551
CAS No.: 1374419-41-6
Synonyms: KBSA301; AR-301

Target:  

Antibiotic Bacterial

Research Areas:  

Infection

Tosatoxumab (AR-301; KBSA301) is a human immunoglobulin G1 monoclonal antibody that specifically neutralizes alpha-toxin (alpha-hemolysin; Hla) of S. aureus. Tosatoxumab binds to an N-terminal epitope of alpha-toxin, thereby preventing functional toxin pore oligomerisation. Tosatoxumab has the potential for passive immunotherapy in the S. aureus pneumonia as an adjunctive therapy to standard antibiotic agent. Recommend Isotope Control: Human IgG1 lambda1, Isotype Control (HY-P99992) .
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