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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
284 Results for "
human insulin
" in MedChemExpress (MCE) Product Catalog:
Products (284)
284 Results for "human insulin" in MCE Product Catalog:
103
103 Publications Verification
Cat. No.: HY-P0035
CAS No.: 11061-68-0
Target:
Research Areas:
103
103 Publications Verification
Cat. No.: HY-P0035A
CAS No.: 11061-68-0
Target:
Research Areas:
32
32 Cited Publications
Research Areas:
NCT-503 is a blood-brain barrier-permeable, non-competitive PHGDH inhibitor with an IC50 of 2.5 μM against human PHGDH. NCT-503 reduces glucose-derived serine production and the incorporation of one-carbon units into nucleotides without decreasing PHGDH protein expression. NCT-503 prevents high selenium-induced insulin resistance in mice by regulating blood glucose and insulin levels and improving glucose tolerance, and also inhibits the growth of tumors overexpressing PHGDH. NCT-503 can be used in research related to insulin resistance and breast cancer .
27
27 Cited Publications
Cat. No.: HY-P73243
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: INS; Proinsulin; Prev. IDDM1; PNDM4; Prev. IDDM2; IDDM; insulin-Dependent Diabetes Mellitus 2; ILPR; Preproinsulin; IRDN; insulin; MODY10
Species:
Source:
27
27 Cited Publications
Cat. No.: HY-P7018
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin Like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-Like Growth Factor 1; insulin-Like Growth Factor IB; insulin-Like Growth Factor I; insulin-Like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-Like
10
10 Cited Publications
Synonyms: 6-Methoxynicotinamide
Target:
Research Areas:
JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease .
9
9 Cited Publications
Cat. No.: HY-P2093
CAS No.: 1083433-49-1
Target:
Research Areas:
9
9 Cited Publications
Cat. No.: HY-P2093B
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6
6 Cited Publications
Cat. No.: HY-P70788
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin Like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-Like Growth Factor 1; insulin-Like Growth Factor IB; insulin-Like Growth Factor I; insulin-Like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-Like
4
4 Cited Publications
Synonyms: Monoaminoethyl phosphate; NSC 254167; O-Phosphoethanolamine
Category:
Natural Products Immune System Disorder Disease markers Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
3
3 Cited Publications
Cat. No.: HY-P7019
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF2; insulin-Like Growth Factor 2 (Somatomedin A); Prev. C11orf43; insulin-Like Growth Factor Type 2; insulin-Like Growth Factor 2; Somatomedin A; IGF-II; Somatomedin-A; insulin-Like Growth Factor II; PP9974; T3M-11-Derived Growth Factor; IGF-2; FLJ44734
3
3 Cited Publications
Cat. No.: HY-110135A
Purity: 99.42%
Target:
Research Areas:
NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (Kis=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .
3
3 Cited Publications
Cat. No.: HY-13967
CAS No.: 865231-46-5
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Research Areas:
AMG 837 is an orally active, selective GPR40/FFA1 agonist with an EC50 of 1.5 nM against human GPR40. AMG 837 stimulates insulin secretion in a glucose-dependent manner, and effectively improves glycemic control in both normal and diabetic rodent models . AMG 837 binds to the BacA protein and impairs the survival and replication of Brucella. AMG 837 can be used in research related to type 2 diabetes and brucellosis .
3
3 Cited Publications
Cat. No.: HY-18555
CAS No.: 1258275-73-8
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Research Areas:
TMPA is a high-affinity Nur77 antagonist that binds to Nur77 leading to the release and shuttling of LKB1 in the cytoplasm to activate AMPKα. TMPA effectively lowers blood glucose and attenuates insulin resistance in type II db/db, high-fat diet and streptozotocin-induced diabetic mice. TMPA reduces RICD (restimulation-induced cell death) in human T cells, can also be used in studies of cancer and T-cell apoptosis dysregulation .
3
3 Cited Publications
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Research Areas:
AMG 837 calcium hydrate is an orally active, selective GPR40/FFA1 agonist with an EC50 of 1.5 nM against human GPR40. AMG 837 calcium hydrate stimulates insulin secretion in a glucose-dependent manner, and effectively improves glycemic control in both normal and diabetic rodent models . AMG 837 calcium hydrate binds to the BacA protein and impairs the survival and replication of Brucella. AMG 837 calcium hydrate can be used in research related to type 2 diabetes and brucellosis .
3
3 Cited Publications
Cat. No.: HY-N0597
CAS No.: 32791-84-7
2
2 Cited Publications
Cat. No.: HY-P0276
CAS No.: 100040-31-1
Synonyms: Gastric Inhibitory Peptide (GIP), human
Target:
Research Areas:
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P70783
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; insulin Like Growth Factor 1; IGF1A; IGF-I; MGF; insulin-Like Growth Factor 1; insulin-Like Growth Factor IB; insulin-Like Growth Factor I; insulin-Like Growth Factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; insulin-Like
2
2 Cited Publications
Cat. No.: HY-P7368
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGFBP2; insulin-Like Growth Factor Binding Protein 2 (36kD); Prev. IBP2; IGF-BP53; insulin-Like Growth Factor-Binding Protein 2; IGFBP-2; insulin-Like Growth Factor Binding Protein 2, 36kDa; IBP-2; IGF-Binding Protein 2; BP2; insulin Like Growth Factor Bi
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
