7150-23-4
Chemical Structure
JBSNF-000088
Synonym(s): 6-Methoxynicotinamide
- CAS No.: 7150-23-4
- Formula:C7H8N2O2
- Molecular Weight:152.15
IUPAC Name: 6-methoxynicotinamide
InChIKey: KXDSMFBEVSJYRF-UHFFFAOYSA-N
SMILES: O=C(N)C1=CC=C(OC)N=C1
Biological Activity: JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JBSNF-000088 | 99.85% | JBSNF-000088 (6-Methoxynicotinamide), a analog of nicotinamide (NA), is a potent and orally active Nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 1.8 µM, 2.8 µM, and 5.0 µM for human NNMT, monkey NNMT and mouse NNMT, respectively. JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization, glucose modulation and body weight reduction in animal models of metabolic disease. | ||||||||||||||||||||
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