2 Results for "

human mesenteric resistance arteries

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "human mesenteric resistance arteries" in MCE Product Catalog:

Cat. No.: HY-P2501
CAS No.: 135702-23-7
Target:  

Amylin Receptor

Research Areas:  

Metabolic Disease

Amylin (8-37), human is a fragment of human Amylin. Amylin (8-37), human has direct vasodilator effects in the isolated mesenteric resistance artery of the rat. Human Amylin is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus .
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Cat. No.: HY-P12136
CAS No.: 1966181-14-5
Synonyms: FE 205030
Target:  

CGRP Receptor

Research Areas:  

Neurological Disease

Fonagepant (FE 205030) is a calcitonin gene-related peptide (CGRP) receptor antagonist with an IC50 of 0.2 nM. Fonagepant selectively blocks CGRP receptor activity, inhibits CGRP-induced vasodilation, attenuates capsaicin-induced increase in skin blood flow, and blocks CGRP-induced vasodilation in isolated human mesenteric resistance arteries. Fonagepant can be used in studies related to acute migraine attacks .
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