1 Result for "

human papillomavirus 16 E6 oncoprotein

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "human papillomavirus 16 E6 oncoprotein" in MCE Product Catalog:

  • Targets Recommended:
L-Penicillamine
L-Penicillamine
0 Images
Cat. No.: HY-116073
CAS No.: 1113-41-3
Target:  

Acyltransferase

Research Areas:  

Infection Cancer

L-Penicillamine is an orally active serine palmitoyltransferase (SPT) inhibitor. L-Penicillamine inactivates the PLP cofactor by forming adducts, thereby inhibiting SPT activity and reducing sphingolipid biosynthesis. L-Penicillamine not only blocks tumor access to vitamin B6, but also stabilizes the human papillomavirus 16 E6 oncoprotein monomer and inhibits its polymerization, exhibiting a unique anticancer mechanism. L-Penicillamine effectively delays the growth of Sarcoma-180, induces tumor necrosis and prolongs survival (though long-term use may lead to Pyridoxine (HY-B1328) deficiency and weight loss) .
loading...
    loading...
View All Sizes
Assay Types