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Results for "

human platelet

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PDGFR (6) Platelet-activating Factor Receptor (PAFR) (21) Acetyl-CoA Carboxylase (1) Adenylate Cyclase (5) Adrenergic Receptor (2) Akt (5) Antibiotic (2) Apoptosis (22) Autophagy (7) Bacterial (10) Bcl-2 Family (1) Biochemical Assay Reagents (11) c-Kit (2) Calcium Channel (7) Carbonic Anhydrase (1) Caspase (2) Cathepsin (2) COX (11) CXCR (2) Cyclin G-associated Kinase (GAK) (1) DNA/RNA Synthesis (5) Dopamine Receptor (5) Drug Derivative (4) Drug Metabolite (5) Endogenous Metabolite (19) Environmental Pollutants (1) ERK (1) Factor VIIa (1) Factor Xa (6) Fc Receptor (FcR) (2) Ferroptosis (2) FLT3 (2) Fluorescent Dye (2) G Protein-coupled Receptor Kinase (GRK) (1) Glutathione Peroxidase (2) Guanylate Cyclase (1) Heme Oxygenase (HO) (2) Histamine Receptor (1) HIV (1) HMG-CoA Reductase (HMGCR) (2) HSP (2) IKK (4) Indoleamine 2,3-Dioxygenase (IDO) (2) Integrin (13) Interleukin Related (1) Isotope-Labeled Compounds (10) Kallikrein (2) Keap1-Nrf2 (3) LDLR (1) Leukotriene Receptor (1) Liposome (3) Lipoxygenase (3) LPL Receptor (2) Monoamine Transporter (6) mRNA (10) Na+/H+ Exchanger (NHE) (10) NF-κB (9) NO Synthase (5) P-glycoprotein (1) P2X Receptor (2) P2Y Receptor (10) p38 MAPK (1) PAI-1 (1) Parasite (4) PARP (1) PCSK9 (2) PDI (1) PGE synthase (4) Phosphodiesterase (PDE) (12) Phospholipase (2) Phosphorylase (1) PKC (4) Potassium Channel (3) Prostaglandin Receptor (29) PROTACs (1) Protease Activated Receptor (PAR) (8) Proteasome (2) Reactive Oxygen Species (ROS) (10) Reference Standards (18) Ser/Thr Protease (3) Serotonin Transporter (1) SphK (1) Syk (3) TGF-β Receptor (2) Thrombin (11) Thrombopoietin Receptor (1) TNF Receptor (2) Toll-like Receptor (TLR) (1) Transmembrane Glycoprotein (1) TRP Channel (1) Tyrosinase (1) UGT (1)
By Research Areas:	Cancer (41) Cardiovascular Disease (123) Endocrinology (10) Infection (14) Inflammation/Immunology (60) Metabolic Disease (16) Neurological Disease (33)
Click Chemistry:	DBCO (5)
Oligonucleotides:	Nucleotide Analogs (3) Aptamers (2) Phospholipids (1) mRNA (10) Adenine Nucleotide (3)

246

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

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Recombinant Proteins

Isotope-Labeled Compounds

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Click Chemistry

Oligonucleotides

Calpeptin Maximum Cited Publications 27 Publications Verification	Cathepsin Proteasome Apoptosis	Inflammation/Immunology
Calpeptin is a potent, cell penetrating calpain inhibitor, with an ID₅₀ of 40 nM for Calpain I in human platelets . Calpeptin is also an inhibitor of cathepsin K .

TA-316 Megakaryocytes/platelets inducing agent	Cyclin G-associated Kinase (GAK)	Cardiovascular Disease
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells .

Compound 48/80 trihydrochloride 5 Publications Verification C48/80 trihydrochloride	Phospholipase	Neurological Disease
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .

Olaratumab IMC-3G3; LY3012207	PDGFR	Cancer
Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity .

RO1138452 CAY10441	Prostaglandin Receptor	Inflammation/Immunology Endocrinology
RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pK_i is 9.3±0.1; in a recombinant IP receptor system, pK_i is 8.7±0.06.

Rondaptivon pegol sodium BT200 sodium	Integrin Apoptosis	Cardiovascular Disease Inflammation/Immunology
Rondaptivon pegol (BT200) sodium is an aptamer targeting von Willebrand factor (VWF), with an EC₅₀ of 33 nM in humans. Rondaptivon pegol sodium effectively alleviates acute myocardial ischemia-reperfusion injury in mice by inhibiting VWF activity, reducing microvascular obstruction, inflammatory responses and cardiomyocyte apoptosis (apoptosis). Rondaptivon pegol sodium inhibits the binding of VWF to platelet glycoprotein GPIb, thereby preventing arterial thrombosis in cynomolgus monkeys. Rondaptivon pegol sodium can be used in research related to arterial thrombosis, stroke, myocardial infarction and myocardial ischemia-reperfusion injury .

2-MeS-ADP trisodium 2-Methylthioadenosine diphosphate trisodium; 2-Methylthio-ADP trisodium	P2Y Receptor	Neurological Disease
2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC₅₀s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC₅₀s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1 .

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine	Liposome	Cardiovascular Disease
1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is a major phospholipid in low-density lipoprotein and belongs to the group of 1-acyl phosphatidylcholines. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine does not induce morphological changes in washed human platelets. 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine can be used for the research of atherosclerosis and thrombotic diseases .

trans-2-Nonenal trans-2-Nonen-1-al	COX Lipoxygenase Apoptosis	Cardiovascular Disease Inflammation/Immunology
trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .

Mudanpioside C	PDI	Cardiovascular Disease
Mudanpioside C is a protein disulfide isomerase (PDI) inhibitor with a human IC₅₀ of 3.31 μM and human K_d of 3.9 μM. Mudanpioside C suppresses collagen-induced platelet aggregation, interferes with platelet activation, adhesion, and spreading. Mudanpioside C can be used for the research of cardiovascular diseases .

Lactodifucotetraose Difucosyllactose ; 2′,3-Difucosyllactose	Endogenous Metabolite	Inflammation/Immunology
Lactodifucotetraose is a difucosylated human milk oligosaccharide. Lactodifucotetraose inhibits platelet function and the release of inflammatory factors. Lactodifucotetraose can be used for the research of Campylobacter jejuni-associated diarrhea and platelet-induced inflammatory processes .

Zoniporide hydrochloride hydrate 2 Publications Verification CP-597396 hydrochloride hydrate	Na+/H+ Exchanger (NHE)	Cardiovascular Disease
Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC₅₀=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC₅₀=59 nM) .

CV-6209	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
CV-6209 is a potent antagonist of platelet activating factor (PAF). CV-6209 inhibits the PAF-induced aggregation of rabbit and human platelets, with IC₅₀s of 75 nM and 170 nM, respectively. CV-6209 can inhibit PAF-induced hypotension in rats .

Foropafant SR27417	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
Foropafant (SR27417) highly potent, competitive, selective and orally active antagonist of platelet-activating factor (PAF) receptor, with a K_i value of 57 pM for [ ³H]PAF binding, at least 5-fold lower than that of unlabeled PAF itself. Foropafant potently inhibits PAF-induced aggregation of rabbit and human platelets .

Sulbenicillin disodium	Antibiotic Bacterial	Infection
Sulbenicillin disodium is a semisynthetic α-sulfonylbenzylpenicillin antibiotic. Sulbenicillin disodium exerts antibacterial activity against multiple gram-negative rods. Sulbenicillin disodium inhibits primary and secondary platelet aggregation, serotonin release from platelets, and platelet adherence via platelet surface coating. Sulbenicillin disodium can be used for the research of Pseudomonas aeruginosa, Pseudomonas maltophilia, and Pseudomonas cepacia infections .

IPG-2 AM APG-2 Acetoxymethyl ester	Fluorescent Dye Potassium Channel	Others
IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .

TCV-309 chloride	Platelet-activating Factor Receptor (PAFR)	Cancer
TCV-309 chloride is a potent and specific platelet activating factor (PAF) antagonist. TCV-309 chloride specifically inhibits PAF-induced aggregation of rabbit and human platelets, and [3H]PAF binding to rabbit platelet microsomes with IC₅₀ values of 33 nM, 58 nM and 27 nM, respectively. TCV-309 chloride has beneficial effects in anaphylactic shock .

DMPQ dihydrochloride	PDGFR	Others
DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC₅₀ of 80 nM .

Clopidogrel carboxylic acid CLPM; SR 26334	Endogenous Metabolite	Metabolic Disease
Clopidogrel carboxylic acid (CLPM) is the inactive liver metabolite of anti platelet agent, Clopidogrel (HY-15283), in human serum .

PAR-4 (1-6) amide (human)	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation .

BMS-191095 1 Publications Verification	Potassium Channel	Cardiovascular Disease Neurological Disease
BMS-191095 is a selective activator of mitochondrial ATP-sensitive potassium (mitoKATP) channels. BMS-191095 inhibits human platelet aggregation by opening mitochondrial K(ATP) channels .

Thromboxane B3	COX Endogenous Metabolite	Endocrinology
Thromboxane B3 is a prostaglandin analog derived from arachidonic acid (AA) in the cyclooxygenase (COX) metabolic pathway. Thromboxane B3 is generated from arachidonic acid (AA) in platelets and vascular endothelial cells through the catalysis of cyclooxygenase (COX) and thromboxane synthase (TXS). Thromboxane B3 has been reported to be formed by human platelets upon ingestion of eicosapentaenoic acid (C20: 5ω3) .

RO3244794	Prostaglandin Receptor	Neurological Disease Inflammation/Immunology
RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pK_i of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential .

NCGC00351170	Factor Xa	Cardiovascular Disease
NCGC00351170 is an antiplatelet agent that disrupts the calcium and integrin-binding protein 1 (CIB1)-α_IIbβ₃ interaction. NCGC00351170 inhibits thrombin-induced human platelet aggregation .

[Rh(cod)Cl]2 Chloro(1,5-cyclooctadiene)rhodium(I) dimer	Biochemical Assay Reagents	Cardiovascular Disease
[Rh(cod)Cl]2 (Chloro(1,5-cyclooctadiene)rhodium(I) dimer) is a rhodium (I) organometallic dimer complex. [Rh(cod)Cl]2 can inhibit platelet-activating factor-mediated platelet aggregation with IC₅₀ values of 5.2 and 43.3 μM in washed rabbit platelets and human platelet-rich plasmas. [Rh(cod)Cl]2 also can inhibit thrombin-, ADP (HY-W010918)- and collagen-induced aggregation with IC₅₀ values of 16.7, 162 and 69.8 μM. [Rh(cod)Cl]2 can be used for the research of cardiovascular disease, such as thrombosis .

(±)20-HDHA (±)20-HDoHE	Endogenous Metabolite	Neurological Disease
(±)20-HDHA ((±)20-HDoHE) is a racemic mixture and is an autoxidation product of Docosahexaenoic acid (DHA). (±)20-HDHA is also formed by peroxidation process in human platelets and rat brain homogenate .

Motapizone NAT 05-239	Phosphodiesterase (PDE)	Inflammation/Immunology
Motapizone (NAT 05-239) is a selective PDE3 inhibitor. Motapizone moderately inhibits cytokine release in lipopolysaccharide (LPS)-induced alveolar macrophages. Motapizone also inhibits human platelet aggregation by increasing intracellular cAMP .

Dabigatran acyl-β-D-glucuronide	Drug Metabolite Thrombin	Cardiovascular Disease
Dabigatran acyl-β-D-glucuronide is an active metabolite of the thrombin inhibitor Dabigatran (HY-10163). Dabigatran acyl-β-D-glucuronide increases activated partial thromboplastin time (aPTT) in isolated human platelet-poor plasma.

Adenosine 2',5'-diphosphate sodium	P2Y Receptor Endogenous Metabolite	Others
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist. Adenosine 2',5'-diphosphate sodium exhibits non-selective antagonism at recombinant and human platelet P2X1 receptors .

Homoeriodictyol 7-O-β-D-glucoside	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC₅₀ of 0.8 μM .

N-Acetyldesloratadine SCH-37370	Platelet-activating Factor Receptor (PAFR) Histamine Receptor	Inflammation/Immunology
N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine. N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC₅₀ of 0.6 µM. N-Acetyldesloratadine can be used for the study of allergic diseases, such as asthma .

MK 287	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
MK 287 is a potent, selective and orally active antagonist of platelet-activating factor receptor (PAFR). MK 287 can inhibit [3H]C18-PAF binding to human platelet, polymorphonuclear leukocyte (PMN) and lung membranes with K1 values of 6.1, 3.2, and 5.49 nM, respectively. MK 287 can inhibit PAF-induced aggregation of platelets in plasma or gel-filtered platelets and elastase release from PMNs with ED₅₀ values of 56, 1.5 and 4.4 nM. MK 287 can be used for the research of cardiovascular disease, such as thrombosis .

KGDS	Integrin	Others
KGDS is synthetic peptides, targeting integrin GPIIb-IIIa located on the membrane of human activated platelets. Amino acid sequence: Lys-Gly-Asp-Ser .

Human α-Thrombin (Lyophilized) 5+ Cited Publications	Thrombin	Cardiovascular Disease
Human α-thrombin is a multifunctional serine protease that plays a pivotal role in the coagulation pathway. Human α-thrombin cleaves fibrinogen and converts it into fibrin. Human α-thrombin can stimulate platelet activation and stabilize fibrin polymers .

SDZ-62-434 free base	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease Cancer
SDZ-62-434 free base is a platelet-activating factor (PAF) antagonist. SDZ-62-434 free base has antiproliferative activity in human solid and haematological malignancies .

FR183998 free base	Na+/H+ Exchanger (NHE)	Cardiovascular Disease Inflammation/Immunology
FR183998 free base is a potent Na ⁺/H ⁺-exchange inhibitor, with IC₅₀s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pH_i change in rat lymphocytes, rat and human platelets, respectively.

NF864	P2X Receptor	Cardiovascular Disease
NF864 is a selectivelyP2X1 receptorinhibitor in human platelets .

MRS2298	P2Y Receptor	Cardiovascular Disease
MRS2298? is a potent acyclic P2Y1 receptor antagonist with a K_i of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC₅₀ of 62.8 nM. MRS2298 inhibits Ca ²⁺ rise in platelets with an IC₅₀ of 810 nM .

15(R)-Prostaglandin D2 15R-PGD2	Prostaglandin Receptor	Inflammation/Immunology
15(R)-Prostaglandin D2 is a potential prostatic hormone DP(2) receptor (Prostaglandin Receptor) agonist with anti-inflammatory activity. 15(R)-Prostaglandin D2 increases actin polymerization in human eosinophils and increases cAMP levels in platelets .

Zoniporide hydrochloride CP-597396 hydrochloride	Na+/H+ Exchanger (NHE)	Cardiovascular Disease
Zoniporide (CP-597396) hydrochloride is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride inhibits human NHE-1 (IC₅₀=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC₅₀=59 nM) .

Zoniporide hydrochloride hydrate (Standard) CP-597396 hydrochloride hydrate (Standard)	Reference Standards Na+/H+ Exchanger (NHE)	Cardiovascular Disease
Zoniporide (hydrochloride hydrate) (Standard) is the analytical standard of Zoniporide (hydrochloride hydrate). This product is intended for research and analytical applications. Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM) .

Furegrelate sodium U-63557A	Prostaglandin Receptor	Cardiovascular Disease
Furegrelate Sodium (U-63557A) is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate Sodium inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC₅₀ of 15 nM. Furegrelate Sodium is being developed as an antiplatelet agent .

Furegrelate U-63557A free acid	Prostaglandin Receptor	Cardiovascular Disease
Furegrelate (U-63557A free acid) is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC₅₀ of 15 nM. Furegrelate is being developed as an antiplatelet agent .

Furegrelate sodium (Standard) U-63557A (Standard)	Prostaglandin Receptor Reference Standards	Cardiovascular Disease
Furegrelate (sodium) (Standard) is the analytical standard of Furegrelate (sodium). This product is intended for research and analytical applications. Furegrelate Sodium (U-63557A) is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate Sodium inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC50 of 15 nM. Furegrelate Sodium is being developed as an antiplatelet agent .

L 651142	Platelet-activating Factor Receptor (PAFR)	Cardiovascular Disease
L 651142 is a weak platelet activating factor (PAF) receptor antagonist. L 651142 inhibits the binding of [ ³H]PAF to rabbit platelet, human platelet or human lung membranes with K_is of 0.839 μM, 1.82 μM, 3.64 μM, respectively .

Fradafiban BIBU-52	Integrin	Cardiovascular Disease
Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a K_d value of 148 nM.

Cat. No.	Product Name	Type

HY-158741

IPG-2 AM

APG-2 Acetoxymethyl ester

Fluorescent Dye

IPG-2 AM (APG-2 Acetoxymethyl ester) is a membrane-permeant acetoxymethyl ester derivative and selective fluorescent potassium ion indicator. IPG-2 AM exhibits fluorescence increases proportional to extracellular potassium ion concentrations. IPG-2 AM enables real-time monitoring of cytosolic free potassium ion fluxes in human platelets and macrophages. IPG-2 AM can be used for the research of intracellular potassium concentration dynamics .

Cat. No.	Product Name	Type

HY-P1956

Human serum albumin

4 Publications Verification

HSA

Biochemical Assay Reagents

Human serum albumin (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant Human Serum Albumin expressed in a microbial expression system.

HY-P1956A

Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)

HSA (Cell culture grade, Endotoxin<0.125 EU/mg)

Biochemical Assay Reagents

Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) (HSA) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO ⁻) in the vascular wall, contributing to the reduction of blood pressure. Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.

HY-W145519

Hydroxyethyl starch (MW170-230 kDa)	Biochemical Assay Reagents
Hydroxyethyl starch (MW170-230 kDa) is a type of hydroxyethyl starch with a molecular weight of 170-230 kDa. A medium-molecular-weight hydroxyethyl starch (HES 200/0.62) exhibits minimal intravascular hydrolysis. The rapidly degradable medium-molecular-weight Hydroxyethyl starch 200/0.5 causes almost no coagulation disorders and improves hemorheological parameters .

HY-W089800

trans-2-Nonenal

trans-2-Nonen-1-al

Biochemical Assay Reagents

trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX, as well as an inducer of apoptosis. trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase, preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid (HY-109590) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis, and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc. .

HY-D1056C5

Lipopolysaccharides, from S. enterica serotype minnesota Re 595 (Re mutant)

LPS, from Salmonella enterica (Serotype minnesota Re 595 (Re mutant))

Biochemical Assay Reagents

Lipopolysaccharides (LPS), from S. enterica (Salmonella enterica) serotype minnesota Re 595 (Re mutant) is prepared from Salmonella enterica strain Re 595 (Re mutant). The structure in the LPS of strain Re 595 was shown to induce secretion and aggregation in human platelets .
It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.

HY-125139

omega-3 Arachidonic acid ethyl ester, in ethanol, 98%

ω-3 Arachidonic acid ethyl ester, in ethanol, 98%; (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester, in ethanol, 98%

Biochemical Assay Reagents

omega-3 Arachidonic acid ethyl ester, in ethanol, 98% is a rare polyunsaturated fatty acid found in very small amounts in dietary sources. Omega-3 fatty acids are known to be essential for the growth and development of infants, and they protect against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune diseases. In human platelet membranes, omega-3 arachidonic acid inhibits arachidonyl-CoA synthetase with a Ki of 14 μM. It also inhibits arachidonoyl-CoA synthetase in calf brain extract with an IC50 of approximately 5 μM. Omega-3 ethyl arachidonate is the more lipophilic form of the free acid.

HY-174935

DBCO-PEG1000-NHS	Biochemical Assay Reagents
DBCO-PEG1000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935A

DBCO-PEG2000-NHS	Biochemical Assay Reagents
DBCO-PEG2000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-135447

BM-531

Biochemical Assay Reagents

BM-531 is a dual-acting agent for thromboxane receptor (TXA2) antagonism and thromboxane synthase inhibition. BM-531 exerts anti-aggregatory effects on human citrated platelet-rich plasma (PRP), inhibiting Arachidonic acid (HY-109590A)-induced aggregation with an ED₁₀₀ of 0.125 μM and U-46619 (HY-108566)-induced aggregation with an ED₅₀ of 0.482 μM. BM-531 inhibits high-K ⁺-induced contraction of porcine uterine smooth muscle .

HY-174935C

DBCO-PEG5000-NHS	Biochemical Assay Reagents
DBCO-PEG5000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935B

DBCO-PEG3400-NHS	Biochemical Assay Reagents
DBCO-PEG3400-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935D

DBCO-PEG10000-NHS	Biochemical Assay Reagents
DBCO-PEG10000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-131384

8,11,14-Eicosatriynoic acid

8,11,14-Icosatriynoic acid

Biochemical Assay Reagents

8,11,14-Eicosatriynoic Acid, as an inhibitor of prostaglandin, leukotriene biosynthesis, and arachidonic acid-induced platelet aggregation, blocks human 12-lipoxygenase (12-LO), cyclooxygenase (COX)and 5-lipoxygenase (5-LO) with IC50 values of 0.46 μM, 14 μMand 25 μM, respectively. In addition, 8,11,14-Eicosatriynoic Acid inhibits the action of slow-reacting substances of allergic reactions, with IC50 value of 10 μM. Lipoxygenase is widely found in fungi, plants and animals. 12-LO involves in many important disease states and may play a role in oxidative glutamate toxicity. COX enzymes play complex roles in human physiology and pathology involving the neuronal, immune, renal, cardiovascular, gastrointestinal and reproductive systems. COX enzymes are blocked by aspirin and a variety of other NSAIDs, which makes them clinically important. 5-LO involves in cancer pathology. It is expressed by a variety of cancer cells, including colon, lung, breast, and prostate cancers, and promotes cancer cell growth and neovascularization . 8,11,14-Eicosatriynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name	Target	Research Area

HY-P0078

TRAP-6 5+ Cited Publications PAR-1 agonist peptide; Thrombin Receptor Activator Peptide 6	Protease Activated Receptor (PAR)	Inflammation/Immunology
TRAP-6 (PAR-1 agonist peptide), a peptide fragment, is a selective protease activating receptor 1 (PAR1) agonist. TRAP-6 activates human platelets via the thrombin receptor. TRAP-6 shows no activity at PAR4 .

HY-P0074

GPRP 3 Publications Verification Gly-Pro-Arg-Pro; Pefa 6003	Thrombin	Cardiovascular Disease
GPRP (Gly-Pro-Arg-Pro; Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction between fibrinogen and the platelet membrane glycoprotein Ⅱb/IIIa complex (glycoprotein IIb/IIIa receptor) . GPRP increases the level of free thrombin in activated platelet-rich plasma by reducing the adsorption of thrombin onto fibrin. GPRP inhibits platelet aggregation and prolongs the thrombin-initiated clotting time in plasma. GPRP is applicable for research related to thrombosis and thrombotic diseases .

HY-122542

PPACK	PAI-1 Thrombin	Inflammation/Immunology
PPACK is a potent, peptidic inhibitor targeting thrombin and granzyme GZMK. PPACK specifically blocks the activities of thrombin and GZMK, thereby inhibiting thrombin-mediated PAR-1 cleavage, as well as downstream inflammatory and procoagulant signaling pathways. Through stabilizing IκB proteins, blocking NF-κB activation and reducing systemic levels of proinflammatory/procoagulant biomarkers, PPACK exerts multiple effects including anti-inflammatory, antithrombotic, barrier repair, and inhibition of atherosclerotic plaque progression. PPACK binds to platelets without interference from kininogen, effectively limiting acute thrombus growth and reducing eosinophil infiltration and goblet cell hyperplasia in asthma models. PPACK is an important tool molecule for investigating the mechanisms of atherosclerosis, asthma and related thromboinflammatory diseases .

HY-P4004

PAR-4 (1-6) amide (human)	Protease Activated Receptor (PAR)	Inflammation/Immunology
PAR-4 (1-6) amide human is an N-terminal fragment of protease-activated receptor 4 (PAR4). PAR-4 (1-6) amide human induce platelet aggregation .

HY-P1798

**Platelet Factor 4 (58-70), human**	Peptides	Cardiovascular Disease
Platelet Factor 4 (58-70), human, a peptide based on the amino acid sequence corresponding to residues 58-70 of platelet factor-4 (PF-4), contains the major heparin-binding domain, which is not sufficient for full antiangiogenic activity .

HY-P3523

KGDS	Integrin	Others
KGDS is synthetic peptides, targeting integrin GPIIb-IIIa located on the membrane of human activated platelets. Amino acid sequence: Lys-Gly-Asp-Ser .

HY-P1702

GR83895	Integrin	Others
GR83895 is a RGD based peptide, and inhibits ADP-induced platelet aggregation of human gel-filtered platelets (IC₅₀= 0.9 μM) .

HY-P5463

C18G	Bacterial	Others
C18G is a biological active peptide. (C18G is a synthetic α-helical peptide derived from human platelet factor IV. This peptide was found to be antibacterial and is active against Salmonella.)

HY-P3006

Des-Leu10-angiotensin I	Drug Metabolite	Cardiovascular Disease
Des-Leu10-angiotensin I is a nonapeptide that inhibits rabbit lung angiotensin-converting enzyme peptidyl-dipeptide hydrolase with a K_i value of 31 μM, which is generated from angiotensin I by the action of carboxypeptidase-like activities residing in the human platelet and mast cell .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9922

Olaratumab IMC-3G3; LY3012207	PDGFR	Cancer
Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity .

HY-P9934

Abciximab 2 Publications Verification C7E3	Integrin	Cardiovascular Disease
Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .

HY-P990859

Anti-CD44 Antibody (Hermes-1) 1 Publications Verification	Transmembrane Glycoprotein	Others
Anti-CD44 Antibody (Hermes-1) is a kind of rat IgG2a κ chimeric antibody, targeting to human CD44. Anti-CD44 Antibody (Hermes-1) blocks the binding of hyaluronan to CD44. Anti-CD44 Antibody (Hermes-1) restores (Platelet-derived Growth Factor-BB)-induced β-receptor activation and motility in fibroblasts. Anti-CD44 Antibody (Hermes-1) causes partial loss of the anti-aging effect of hyaluronic .

HY-P99121

Anti-Mouse/Human CD11b Antibody (M1/70)	Integrin	Inflammation/Immunology Cancer
Anti-Mouse/Human CD11b Antibody (M1/70) is an anti-mouse CD11b IgG2b monoclonal antibody. Anti-Mouse/Human CD11b Antibody (M1/70) can significantly inhibit the adhesion between dendritic cells (DCs) and platelets. Anti-Mouse/Human CD11b Antibody (M1/70) can kill ovarian cancer cells and inhibit their migration. Anti-Mouse/Human CD11b Antibody (M1/70) can alleviate renal fibrosis and inflammation. Anti-Mouse/Human CD11b Antibody (M1/70) can be used for researches on inflammation conditions and cancer such as ischemia-reperfusion injury (IRI), thrombotic inflammatory conditions and ovarian cancer .

HY-P991998

Anti-Human/Monkey CD16a Antibody (3G8)	Fc Receptor (FcR)	Inflammation/Immunology Cancer
Anti-Human/Monkey CD16a Antibody (3G8) is a monoclonal antibody targeting CD16a. Anti-Human/Monkey CD16a Antibody (3G8) blocks FcγRIII/CD16a, upregulates the metabolic activity of CD16+ cells, downregulates CD87, a poor prognostic marker, and inhibits the engraftment and growth of leukemia cells in acute myeloid leukemia, and rapidly increases platelet counts in immune thrombocytopenia. Anti-Human/Monkey CD16a Antibody (3G8) is applicable to research related to tumor immunology .

HY-P992152

Vatreptacog alfa	Factor VIIa Drug Derivative	Cardiovascular Disease
Vatreptacog alfa is a recombinant hFVIIa analog, differing from native FVIIa by three amino acid substitutions (V158D, E296V and M298Q) in the protease domain. Vatreptacog alfa exhibits enhanced tissue factor-independent enzymatic activity toward activated platelets. Vatreptacog alfa can be used in the research of hemophilia .

HY-P991921

TNX-1500	TNF Receptor Fc Receptor (FcR)	Cardiovascular Disease Endocrinology
TNX-1500 is a crystallizable fragment-modified anti-CD154 antibody. TNX-1500 contains the hu5c8 fragment antigen-binding (Fab) domain from Ruplizumab (HY-P99315) and an IgG4 Fc region engineered to reduce FcγRIIa binding. TNX-1500 has significantly weaker binding affinity to FcγRI, FcγRIIaH, FcγRIIbF, FcγRIIIaF, and FcγRIIIaV compared to hu5c8 (K_d values: 8.7 nM, 7100 nM, 4900 nM, 8000 nM, 6000 nM respectively). TNX-1500 prolongs nonhuman primate renal allograft survival, prolongs nonhuman primate cardiac allograft survival. TNX-1500 can be used for the research of allograft rejection ^[1] ^[2].

Species:	Human (45)
Tag:	His (30) Tag Free (5) Avi (8) Myc (2) GST (1) Fc (10)
Source:	HEK293 (31) E. coli Cell-free (1) CHO (2) Sf9 insect cells (3) P. pastoris (3) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P73707

	Pleckstrin Protein, Human (His) Pleckstrin; p47; PLEK; platelet 47 kDa protein	Human	E. coli
	Pleckstrin Protein serves as a primary substrate for protein kinase C in platelets. Pleckstrin Protein, Human (His) is the recombinant human-derived Pleckstrin protein, expressed by E. coli , with N-His labeled tag.

HY-P7280

	PDGF-DD Protein, Human (CHO) 3 Publications Verification rHuPDGF-DD; platelet-derived growth factor D; SCDGFB	Human	CHO
	PDGF-DD Protein, Human (CHO) is a member of the PDGF family, specifically binds to and activates its cognate receptor PDGFR-β, and participates in regulating cancer proliferation, transformation, and invasion through activating multiple downstream oncogenic pathways, resulting in tumor development and progression.

HY-P74643

	PDGF-AA Protein, Human (P.pastoris, His) platelet-derived growth factor subunit A; PDGF-1; PDGFA	Human	P. pastoris
	PDGF-A protein is a key growth factor that regulates embryonic development, cell proliferation, migration, survival, and chemotaxis, and exerts potent mitogenic effects on mesenchymal cells. It is essential for alveolar septal formation, gastrointestinal tract development, interstitial cell maturation, spermatogenesis, and oligodendrocyte development, and contributes to spinal cord and cerebellar myelination. PDGF-AA Protein, Human (P.pastoris, His) is the recombinant human-derived PDGF-AA protein, expressed by P. pastoris , with N-His labeled tag.

HY-P73353

	PDGF-CC Protein, Human (HEK293, Fc) PDGF-C; platelet derived growth factor C; VEGF-E; SCDGF	Human	HEK293
	PDGF-CC is a multifunctional growth factor that plays a crucial role in embryonic development, cellular processes, and tissue formation. It is essential for embryonic skeletal development, skin morphogenesis, and wound healing. PDGF-CC Protein, Human (HEK293, Fc) is the recombinant human-derived PDGF-CC protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P702756

	PDGF R beta Protein, Human (Active, Biotinylated, sf9, His, Avi) PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1	Human	Sf9 insect cells
	PDGF Rβ protein is integral in embryonic development and regulates cell proliferation, survival, differentiation, chemotaxis, migration, and vascular development. It crucially recruits pericytes and smooth muscle cells to the endothelium, promoting vascular smooth muscle cell migration and neointimal formation at the site of injury. PDGF R beta Protein, Human (Biotinylated, sf9, His, Avi) is the recombinant human-derived PDGF R beta, expressed by Sf9 insect cells, with Avi, His labeled tag.

HY-P72076

	ALOX12 Protein, Human (His) 1 Publications Verification 12 LOX; 12S; lipoxygenase ; 12-lipoxygenase; 12LO; 12S LOX; 12S-lipoxygenase; 12S-LOX; 12S-type; Alox12; Arachidonate 12 lipoxygenase; Arachidonate 12 lipoxygenase, 12S type; Arachidonate 12-lipoxygenase; Arachidonate 12-oxidoreductase; Lipoxin synthase 12-LO; LOG12; LOX12_human; P-12LO; platelet 12-LOX; platelet type lipoxygenase 12 ; platelet-type 12-lipoxygenase; platelet-type lipoxygenase 12	Human	E. coli
	ALOX12 Protein, Human (His) is a recombinant ALOX12 protein with a His tag. ALOX12 encodes arachidonic acid 12-lipoxygenase that acts on different polyunsaturated fatty acid substrates to produce biologically active lipid mediators including eicosanes and lipoxins.

HY-P72892

	CD31/PECAM-1 Protein, Human (HEK293) 1 Publications Verification platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; PECA1; CD31	Human	HEK293
	CD31/PECAM-1 Protein, a pivotal cell adhesion molecule, is essential for leukocyte transendothelial migration (TEM) in most inflammatory conditions. PECAM1 modulates bradykinin receptor BDKRB2 activation and regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Signaling through PECAM-1 leads to the activation of neutrophils, monocytes and leukocytes. CD31/PECAM-1 Protein, Human (HEK293) is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with tag free.

HY-P73351

	PDGF-BB Protein, Human (P.pastoris, His) 1 Publications Verification platelet-derived growth factor subunit B; PDGF subunit B; PDGF2; PDGFB; SIS	Human	P. pastoris
	The PDGF-BB protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. It is known for its potent mitogenic effects on mesenchymal cells and is essential for the normal proliferation and recruitment of pericytes and vascular smooth muscle cells in tissues such as the central nervous system, skin, lungs, heart, and placenta. PDGF-BB Protein, Human (P.pastoris, His) is the recombinant human-derived PDGF-BB protein, expressed by P. pastoris , with N-His labeled tag.

HY-P75971

	PFKP Protein, Human (sf9, His-GST) ATP-dependent 6-phosphofructokinase, platelet type; ATP-PFK; PFK-P; PFK-C; PFKP	Human	Sf9 insect cells
	PFKP protein, central to cellular energy metabolism, catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, initiating glycolysis. This key enzymatic step regulates glucose entry into glycolysis, initiating essential biochemical reactions for ATP and metabolite generation. PFKP's importance in orchestrating this process highlights its central role in cellular energy homeostasis and broader metabolic regulation. PFKP Protein, Human (sf9, His-GST) is the recombinant human-derived PFKP protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag.

HY-P76059

	Serglycin/SRGN Protein, Human (HEK293, His) 1 Publications Verification Hematopoietic proteoglycan core protein; platelet proteoglycan core protein; P.PG; SRGN; PRG; PRG1	Human	HEK293
	Serglycin/SRGN Protein, Human (HEK293, His) is the recombinant human-derived Serglycin/SRGN, expressed by HEK293 , with C-10*His labeled tag. ,

HY-P73351Y

	PDGF-BB Protein, Human (P.pastoris, His, solution) platelet-derived growth factor subunit B; PDGF subunit B; PDGF2; PDGFB; SIS	Human	P. pastoris
	The PDGF-BB protein is a key growth factor that centrally regulates embryonic development, cell proliferation, migration, survival, and chemotaxis. It is known for its potent mitogenic effects on mesenchymal cells and is essential for the normal proliferation and recruitment of pericytes and vascular smooth muscle cells in tissues such as the central nervous system, skin, lungs, heart, and placenta. PDGF-BB Protein, Human (P.pastoris, His) is the recombinant human-derived PDGF-BB protein, expressed by P. pastoris , with N-His labeled tag.

HY-P76058

	Serglycin/SRGN Protein, Human (HEK293, His-Myc) 1 Publications Verification Hematopoietic proteoglycan core protein; platelet proteoglycan core protein; P.PG; SRGN; PRG; PRG1	Human	HEK293
	Serine (SRGN) is essential for the formation of mast cell secretory granules and the storage of various compounds. It plays a crucial role in the storage of proteases in mast cells, including granzyme B in T lymphocytes, and contributes to the localization of neutrophil elastase. Serglycin/SRGN Protein, Human (HEK293, His-Myc) is the recombinant human-derived Serglycin/SRGN protein, expressed by HEK293 , with C-His, C-Myc labeled tag.

HY-P76805

	CD42c/GP1BB Protein, Human (HEK293, His) platelet glycoprotein Ib beta chain; GPIb-beta; CD42b-beta	Human	HEK293
	CD42c/GP1BB protein, present on platelets, interacts with von Willebrand factor to form platelet plugs. It forms a heterodimer with GP1B beta subunits and associates with GP-IX, facilitating platelet adhesion and initiating thrombus formation. CD42c also interacts with TRAF4, potentially regulating cellular signaling pathways. CD42c/GP1BB Protein, Human (HEK293, His) is the recombinant human-derived CD42c/GP1BB protein, expressed by HEK293 , with C-His labeled tag.

HY-P73356

	PDGF R alpha Protein, Human (HEK293, Fc) platelet-derived growth factor receptor alpha; PDGFR-alpha; PDGFR-2; CD140a; PDGFRA	Human	HEK293
	PDGF R α is a tyrosine protein kinase and an important cell surface receptor for PDGFA, PDGFB and PDGFC, affecting embryonic development, cell proliferation, survival and chemotaxis. Its effects on cell behavior vary, promoting or inhibiting proliferation and migration depending on environmental cues. PDGF R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived PDGF R alpha protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P705395

	GP5 Protein, Human (Biotinylated, HEK293, His-Avi) platelet glycoprotein V; GP5; Glycoprotein 5; CD42d; GPV	Human	HEK293

HY-P70948

	JAM-A/CD321 Protein, Human (HEK293, His) Junctional Adhesion Molecule A; JAM-A; Junctional Adhesion Molecule 1; JAM-1; platelet F11 Receptor; platelet Adhesion Molecule 1; PAM-1; CD321; F11R; JAM1; JCAM	Human	HEK293
	The JAM-A/CD321 protein is critical for the formation of epithelial tight junctions, is present in early junction development, and recruits PARD3. Binding of the PARD6-PARD3 complex may hinder PARD3-JAM1 interaction, thereby impeding tight junction assembly. JAM-A/CD321 Protein, Human (HEK293, His) is the recombinant human-derived JAM-A/CD321 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72494

	PDGF R beta Protein, Human (HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (HEK293, His) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P72495

	PDGF R alpha Protein, Human (HEK293, His) platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-2; CD140a; PDGFRA	Human	HEK293
	PDGF R α is a tyrosine protein kinase and an important cell surface receptor for PDGFA, PDGFB and PDGFC, affecting embryonic development, cell proliferation, survival and chemotaxis. Its effects on cell behavior vary, promoting or inhibiting proliferation and migration depending on environmental cues. PDGF R alpha Protein, Human (HEK293, His) is the recombinant human-derived PDGF R alpha protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77124

	PDGF R beta Protein, Human (HEK293, Fc) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (HEK293, Fc) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P7268

	NAP-2/CXCL7 Protein, Human rHuNAP-2/CXCL7; C-X-C motif chemokine 7; platelet basic protein; MDGF; SCYB7	Human	E. coli
	CXCL7 (also known as neutrophil activating peptide 2, NAP-2) is a platelet-derived growth factor that belongs to the ELR⁺ CXC chemokine family, functioning as a potent chemoattractant and activator of neutrophils through binding to its receptor CXCR2. NAP-2/CXCL7 Protein, Human is produced in E. coli , and consists of 70 amino acids (A59-D128).

HY-P77123

	PDGF R beta Protein, Human (HEK293, His-Avi) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	PDGF Rβ protein is integral in embryonic development and regulates cell proliferation, survival, differentiation, chemotaxis, migration, and vascular development. It crucially recruits pericytes and smooth muscle cells to the endothelium, promoting vascular smooth muscle cell migration and neointimal formation at the site of injury. PDGF R beta Protein, Human (HEK293, His-Avi) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P70988

	CD31/PECAM-1 Protein, Human (HEK293, Fc) platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1	Human	HEK293
	CD31/PECAM-1 is a cell-cell adhesion protein. CD31/PECAM-1 regulates the activation of the slow hormone receptor BDKRB2 in endothelial cells and the activation of ERK1/2 induced by hypertonic shock and induces susceptibility to atherosclerosis. CD31/PECAM-1 mediates adhesion to endothelial cells and regulates tumor growth by forming new endothelial cell tubes. CD31/PECAM-1 Protein, Human (HEK293, Fc) is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77127

	PDGF R beta Protein, Human (Biotinylated, HEK293, His) platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB	Human	HEK293
	TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-His labeled tag.

HY-P7267

	NAP-2/CXCL7 Protein, Human (CHO) 1 Publications Verification rHuNAP-2/CXCL7; C-X-C motif chemokine 7; platelet basic protein; MDGF; SCYB7	Human	CHO
	CXCL7 (also known as neutrophil activating peptide 2, NAP-2) is a platelet-derived growth factor that belongs to the ELR⁺ CXC chemokine family, functioning as a potent chemoattractant and activator of neutrophils through binding to its receptor CXCR2. NAP-2/CXCL7 Protein, Human (CHO) is produced in CHO cells, and consists of 70 amino acids (A59-D128) .

HY-P72490

	CD31/PECAM-1 Protein, Human (HEK293, His) platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA; PECA1; CD31; PECAM1	Human	HEK293
	CD31/PECAM-1 Protein is a cell-cell adhesion protein that is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. CD31/PECAM-1 Protein, Human (HEK293, His) is the recombinant human-derived CD31/PECAM-1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P76539

	PF4V1 Protein, Human (HEK293, Fc) platelet factor 4 variant; CXCL4L1; PF4var1; SCYB4V1	Human	HEK293
	PF4V1, also known as CXCL4L1, is a non-allelic variant of CXCL4. PF4V1 is a platelet-associated chemokine, and it binds to heparin is much weaker than in the close homolog PF4/CXCL4. PF4V1 is an inhibitor of angiogenesis and inhibitor of endothelial cell chemotaxis. PF4V1 is involved in inflammation, angiogenesis, and cancer. PF4V1 Protein, Human (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 104 amino acids (M1-S104).

HY-P700049AF

	Animal-Free NAP-2/CXCL7 Protein, Human (His) NAP-2/CXCL7; C-X-C motif chemokine 7; platelet basic protein; MDGF; SCYB7	Human	E. coli
	NAP-2/CXCL7 protein (LA-PF4) triggers DNA synthesis, mitosis, glycolysis, cAMP accumulation, and hyaluronic acid synthesis. It contributes to the formation of plasminogen activator in human synovial cells and acts as a CXCR1/CXCR2 ligand together with variants such as NAP-2 (73). Animal-Free NAP-2/CXCL7 Protein, Human (His) is the recombinant human-derived animal-FreeNAP-2/CXCL7 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P705568

	PDGF R alpha Protein, Human (Active, Biotinylated, HEK293, His-Avi) platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; EC:2.7.10.1	Human	Sf9 insect cells

HY-P702447

	SMPD2 Protein, Human (Cell-Free, His) Sphingomyelin phosphodiesterase 2; Lyso-platelet-activating factor-phospholipase C; Lyso-PAF-PLC; Neutral sphingomyelinase; N-SMase; nSMase; nSMase1	Human	E. coli Cell-free
	In vitro experiments have demonstrated that the sphingomyelin phosphodiesterase 2 (SMPD2) protein plays a key role in catalyzing the hydrolysis of sphingomyelin, leading to the formation of ceramide and phosphocholine. Furthermore, SMPD2 exhibits its enzymatic activity by hydrolyzing 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (hemolytic platelet-activating factor) in vivo. SMPD2 Protein, Human (Cell-Free, His) is the recombinant human-derived SMPD2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

HY-P78936

	VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P704262

	CD38 Protein, Human (HEK293, mFc) VISTA; B7-H5; platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	The CD38 protein plays a key role in cell signaling, proficiently synthesizing cyclic ADP-ribose (cADPR) as a critical second messenger for glucose-induced insulin secretion. It also promotes the synthesis of the calcium mobilizer niacin-adenine dinucleotide phosphate (NAADP+). CD38 Protein, Human (HEK293, mFc) is the recombinant human-derived CD38 protein, expressed by HEK293, with C-mFc labeled tag.

HY-P75785

	G6B Protein, Human (HEK293, His) Megakaryocyte and platelet inhibitory receptor G6b; Protein G6b; MPIG6B; C6orf25; G6B-B	Human	HEK293
	The G6B protein is an inhibitory receptor critical for hematopoietic lineage differentiation, megakaryocyte function, and platelet production. Its effects include inhibiting platelet aggregation and activation induced by agonists such as ADP and collagen-related peptides. G6B Protein, Human (HEK293, His) is the recombinant human-derived G6B protein, expressed by HEK293 , with C-His labeled tag.

HY-P75784

	G6B Protein, Human (HEK293, Fc) Megakaryocyte and platelet inhibitory receptor G6b; Protein G6b; MPIG6B; C6orf25; G6B-B	Human	HEK293
	The G6B protein is an inhibitory receptor critical for hematopoietic lineage differentiation, megakaryocyte function, and platelet production. Its effects include inhibiting platelet aggregation and activation induced by agonists such as ADP and collagen-related peptides. G6B Protein, Human (HEK293, Fc) is the recombinant human-derived G6B protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P705920

	PF-4/CXCL4 Protein, Human (His) platelet Factor 4; PF-4; C-X-C Motif Chemokine 4; Iroplact; Oncostatin-A; PF4; CXCL4; SCYB4	Human	HEK293
	PF-4/CXCL4 is a member of the CXC chemokine family that is released from the alpha-granules of activated platelets. PF-4/CXCL4 binds with high affinity to heparin, with antiheparin, antiangiogenic and immunomodulatory activities. PF-4/CXCL4 plays a role in hematopoiesis and immune cell modulation. PF-4/CXCL4 Protein, Human (His) is produced in E.coli cells with N-6*His tag.

HY-P70983

	VISTA/B7-H5 Protein, Human (HEK293, His) VISTA; B7-H5; platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; C10orf54; SISP1	Human	HEK293
	VISTA/B7-H5 protein, an immunoregulatory receptor, inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling. It also stimulates MMP14-mediated MMP2 activation, suggesting a role in matrix metalloproteinase processes. These roles highlight the significance of VISTA/B7-H5 in immune regulation, embryonic development, and extracellular matrix dynamics. VISTA/B7-H5 Protein, Human (HEK293, His) is the recombinant human-derived VISTA/B7-H5 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P70618

	PF-4/CXCL4 Protein, Human (HEK293, His) 2 Publications Verification platelet Factor 4; PF-4; C-X-C Motif Chemokine 4; Iroplact; Oncostatin-A; PF4; CXCL4; SCYB4	Human	HEK293
	PF-4/CXCL4 is a member of the CXC chemokine family that is released from the alpha-granules of activated platelets. PF-4/CXCL4 binds with high affinity to heparin, with antiheparin, antiangiogenic and immunomodulatory activities. PF-4/CXCL4 plays a role in hematopoiesis and immune cell modulation. PF-4/CXCL4 Protein, Human (HEK293, His) is produced in HEK293 cells with six C-Terminal His-tags. It consists of 70 amino acids (E32-S101).

HY-P704743

	CD151 Protein-VLP, Human (HEK293) CD151; CD151 antigen; GP27; Membrane glycoprotein SFA-1; platelet-endothelial tetraspan antigen 3 (PETA-3); Tetraspanin-24 (Tspan-24); TSPAN24	Human	HEK293
	CD151 Protein-VLP, Human (HEK293) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

HY-P705623

	CD36 Protein, Human (HEK293, His) rHuplatelet glycoprotein 4/CD36, Fc; Fatty acid translocase; Glycoprotein IIIb; FATCHDS7; Leukocyte differentiation antigen CD36; PAS IV; platelet collagen receptor; SCARB3; Thrombospondin receptor; CD36	Human	HEK293

HY-P70004

	CD36 Protein, Human (HEK293, Fc ) 2 Publications Verification rHuplatelet glycoprotein 4/CD36, Fc; Fatty acid translocase; Glycoprotein IIIb; FATCHDS7; Leukocyte differentiation antigen CD36; PAS IV; platelet collagen receptor; SCARB3; Thrombospondin receptor; CD36	Human	HEK293
	CD36 is a multifunctional glycoprotein that serves as a receptor for a variety of ligands, including thrombospondin and oxidized low-density lipoprotein. Ligand induces CD36 clusters, initiating signal transduction and internalization. CD36 Protein, Human (HEK293, Fc ) is the recombinant human-derived CD36 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P78909

	CD36 Protein, Human (Biotinylated, HEK293, His-Avi) CD36; SCARB3; BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; platelet Glycoprotein 4; glycoprotein IV; gpIV; glycoprotein IIIb; gpIIIb	Human	HEK293
	CD36 is a multifunctional glycoprotein that serves as a receptor for a variety of ligands, including thrombospondin and oxidized low-density lipoprotein. Ligand induces CD36 clusters, initiating signal transduction and internalization. CD36 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CD36 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P705211

	CD36 Protein, Human (Biotinylated, HEK293, Fc-Avi) CD36; SCARB3; BDPLT10; CHDS7; FAT; GP3B; GP4; GPIV; PASIV; platelet Glycoprotein 4; glycoprotein IV; gpIV; glycoprotein IIIb; gpIIIb	Human	HEK293

HY-P71185

	PAFAHB Protein, Human (His) platelet-Activating Factor Acetylhydrolase IB Subunit Beta; PAF Acetylhydrolase 30 kDa Subunit; PAF-AH 30 kDa Subunit; PAF-AH Subunit Beta; PAFAH Subunit Beta; PAFAH1B2; PAFAHB	Human	E. coli
	PAFAHB Proteinas, incorporating Alpha-2 adrenergic receptors, facilitates catecholamine-induced adenylate cyclase inhibition through G proteins. Notably, oxymetazoline ranks as the most potent agonist, followed by clonidine and antagonists with yohimbine exhibiting the highest inhibitory activity. This insight into agonist and antagonist effectiveness sheds light on the pharmacological modulation of Alpha-2 adrenergic receptors by ADRA2A-VLPs. PAFAHB Protein, Human (His) is the recombinant human-derived PAFAHB protein, expressed by E. coli , with C-6*His labeled tag.

HY-P70993

	PLA2G7 Protein, Human (HEK293, His) platelet-Activating Factor Acetylhydrolase; PAF Acetylhydrolase; 1-Alkyl-2-Acetylglycerophosphocholine Esterase; 2-Acetyl-1-Alkylglycerophosphocholine Esterase; Group-VIIA Phospholipase A2; gVIIA-PLA2; LDL-Associated Phospholipase A2; LDL-PLA(2); PAF 2-Acylhydrol	Human	HEK293
	PLA2G7 Protein is a lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress responses. It is also a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. PLA2G7 can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. PLA2G7 Protein, Human (HEK293, His) is the recombinant human-derived PLA2G7 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P703946

	CD109/CPAMD7 Protein, Human (Biotinylated, HEK293, His, Avi) CD109; CPAMD7; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; 150 kDa TGF-beta-1-binding protein; r150; p180; CPAMD7; platelet-specific Gov antigen	Human	HEK293
	CD109/CPAMD7 Protein, Human (Biotinylated, HEK293, His, Avi) is the recombinant human-derived CD109/CPAMD7 protein, expressed by HEK293, with C-His & C-Avi tag.

HY-P700441

	DNAM-1 Protein, Human (HEK293, hFc, Myc) CD226; CD226 molecule; CD226 antigen; DNAM 1; DNAM1; PTA1; TLiSA1; adhesion glycoprotein; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen; DNAM-1	Human	HEK293
	DNAM-1 protein is a key player in cell-cell adhesion and lymphocyte signaling, mediating cytotoxicity and lymphokine secretion of CTL and NK cells. As a receptor for NECTIN2, DNAM-1 stimulates T cell proliferation and cytokine production (IL2, IL5, IL10, IL13, and IFNG) upon ligand binding. DNAM-1 Protein, Human (HEK293, hFc, Myc) is the recombinant human-derived DNAM-1 protein, expressed by HEK293 , with C-Myc, C-hFc labeled tag.

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Source
Tag
Accession
Gene ID
Molecular Weight
Purity
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Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Host:	Rat (1) Mouse (8) Rabbit (6)
Reactivity:	Human (12) Rat (5) Mouse (7)
Application:	IHC-P (10) ICC/IF (4) IF-Tissue (3) IP (1) IHC-F (4) WB (13) FC (6)
Isotype:	IgG (8) IgG1 (6) IgG2a (1)
Conjugation:	Non-conjugated (15) Biotin (8)
Clonality:	Monoclonal (11) Recombinant (7)
Modification:	Phosphorylated (1) Unmodified (10)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86724

	CD41 Antibody (YA6416) platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; platelet fibrinogen receptor alpha; platelet fibrinogen receptor alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet specific antigen bak; ITA2B_human.	WB, FC	Human
	CD41 Antibody (YA6416) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD41.

HY-P86724A

	CD41 Antibody (YA6416)(PBS only) platelet glycoprotein IIb of IIb/IIIa complex; Integrin, alpha 2b(platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GPIIb; GTA; HPA3; CD 41; CD41 antigen; CD41a; CD41b; GP2b; GPalpha IIb; GPalphaIIb; Integrin alpha IIb; Integrin alpha IIb precursor; ITGA 2B; Integrin alpha 2b; ITGAB; platelet fibrinogen receptor alpha; platelet fibrinogen receptor alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet specific antigen bak; ITA2B_human.	WB, FC	Human
	CD41 Antibody (YA6416) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD41.

HY-P86661

	PDGFR alpha Antibody (YA6353) PDGF Receptor alpha; platelet–dirived growth factor receptor-alpha; alpha platelet derived growth factor receptor; CD 140a; CD140a; CD140a antigen; MGC74795; PDGF alpha chain; PDGF R alpha; PDGFR 2; PDGFR A; PDGFR alpha; PDGFR2; platelet derived growth factor receptor 2; platelet derived growth factor receptor alpha; platelet derived growth factor receptor alpha polypeptide; PGFRA_human.	WB	Human, Mouse, Rat
	PDGFR alpha Antibody (YA6353) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PDGFR alpha.

HY-P810616

	Thymidine Phosphorylase Antibody (YA9878) ECGF 1; ECGF; ECGF1; Endothelial cell growth factor 1; Endothelial cell growth factor 1 platelet derived; Endothelial cell growth factor, platelet-derived; Gliostatin; hPD ECGF; MEDPS1; MNGIE; ECGF 1; ECGF; ECGF1; Endothelial cell growth factor 1; Endothelial cell growth factor 1 platelet derived; Endothelial cell growth factor, platelet-derived; Gliostatin; hPD ECGF; MEDPS1; MNGIE; MTDPS1; PD ECGF; PD-ECGF; PDECGF; PDEGF; platelet derived endothelial cell growth factor; platelet derived endothelial growth factor; platelet-derived endothelial cell growth factor; TdRPase; Thymidine phosphorylase; TP; Tymp; TYPH_human	WB, IHC-P	Human
	Thymidine Phosphorylase Antibody (YA9878) is a Mouse-derived and non-conjugated IgG1 Monoclonal antibody, targeting to Thymidine Phosphorylase.

HY-P810617

	Thymidine Phosphorylase Antibody (YA9879) ECGF 1; ECGF; ECGF1; Endothelial cell growth factor 1; Endothelial cell growth factor 1 platelet derived; Endothelial cell growth factor, platelet-derived; Gliostatin; hPD ECGF; MEDPS1; MNGIE; ECGF 1; ECGF; ECGF1; Endothelial cell growth factor 1; Endothelial cell growth factor 1 platelet derived; Endothelial cell growth factor, platelet-derived; Gliostatin; hPD ECGF; MEDPS1; MNGIE; MTDPS1; PD ECGF; PD-ECGF; PDECGF; PDEGF; platelet derived endothelial cell growth factor; platelet derived endothelial growth factor; platelet-derived endothelial cell growth factor; TdRPase; Thymidine phosphorylase; TP; Tymp; TYPH_human	WB, IHC-P	Human, Mouse, Rat
	Thymidine Phosphorylase Antibody (YA9879) is a Mouse-derived and non-conjugated IgG2a Monoclonal antibody, targeting to Thymidine Phosphorylase.

HY-P86711

	CD31 Antibody (YA6403) platelet endothelial cell adhesion molecule precursor-1; PECAM-1; PECAM1; Adhesion molecule; CD31 antigen; CD31 EndoCAM; Endocam; FLJ34100; FLJ58394; GPIIA; Pecam 1; PECA1_human; PECAM 1 CD31 EndoCAM; PECA1; Pecam1; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1; Adhesion molecule; platelet/endothelial cell adhesion molecule.	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Human
	CD31 Antibody (YA6403) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CD31.

HY-P86703

	CD31 Antibody (YA6395) platelet endothelial cell adhesion molecule precursor-1; PECAM-1; PECAM1; Adhesion molecule; CD31 antigen; CD31 EndoCAM; Endocam; FLJ34100; FLJ58394; GPIIA; Pecam 1; PECA1_human; PECAM 1 CD31 EndoCAM; PECA1; Pecam1; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1; Adhesion molecule; platelet/endothelial cell adhesion molecule.	WB, IHC-P, IHC-F, IF-Tissue	Human
	CD31 Antibody (YA6395) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD31.

HY-P86711A

	CD31 Antibody (YA6403)(PBS only) platelet endothelial cell adhesion molecule precursor-1; PECAM-1; PECAM1; Adhesion molecule; CD31 antigen; CD31 EndoCAM; Endocam; FLJ34100; FLJ58394; GPIIA; Pecam 1; PECA1_human; PECAM 1 CD31 EndoCAM; PECA1; Pecam1; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule 1; Adhesion molecule; platelet/endothelial cell adhesion molecule.	WB, IHC-P, IHC-F, ICC/IF, IF-Tissue, FC	Human
	CD31 Antibody (YA6403) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CD31.

HY-P87125

	Thymidine Phosphorylase Antibody (YA6818) ECGF 1 antibody; ECGF antibody; ECGF1 antibody; Endothelial cell growth factor 1 antibody; Endothelial cell growth factor 1 platelet derived antibody; Endothelial cell growth factor, platelet-derived antibody; Gliostatin antibody; hPD ECGF antibody; MEDPS1 antibody; MNGIE antibody; ECGF 1 antibody; ECGF antibody; ECGF1 antibody; Endothelial cell growth factor 1 antibody; Endothelial cell growth factor 1 platelet derived antibody; Endothelial cell growth factor, platelet-derived antibody; Gliostatin antibody; hPD ECGF antibody; MEDPS1 antibody; MNGIE antibody; MTDPS1 antibody; PD ECGF antibody; PD-ECGF antibody; PDECGF antibody; PDEGF antibody; platelet derived endothelial cell growth factor antibody; platelet derived endothelial growth factor antibody; platelet-derived endothelial cell growth factor antibody; TdRPase antibody; Thymidine phosphorylase antibody; TP antibody; Tymp antibody; TYPH_human antibody;	WB, IHC-P	Human, Mouse, Rat
	Thymidine Phosphorylase Antibody (YA6818) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Thymidine Phosphorylase.

HY-P86807

	CD42a Antibody (YA6500) CD42a antibody; Glycoprotein 9 antibody; Glycoprotein IX antibody; Glycoprotein IX (platelet) antibody; Glycoprotein IX precursor antibody; GP IX antibody; GP-IX antibody; GP9 antibody; GPIX antibody; GPIX_human antibody; CD42a antibody; Glycoprotein 9 antibody; Glycoprotein IX antibody; Glycoprotein IX (platelet) antibody; Glycoprotein IX precursor antibody; GP IX antibody; GP-IX antibody; GP9 antibody; GPIX antibody; GPIX_human antibody; platelet glycoprotein IX antibody;	WB, IHC-P	Human, Mouse, Rat
	CD42a Antibody (YA6500) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD42a.

HY-P87029

	Phospho-PDGFR beta (Y1021) Antibody (YA6722) Beta platelet derived growth factor receptor antibody; Beta-type platelet-derived growth factor receptor antibody; CD 140B antibody; CD140 antigen-like family member B antibody; CD140b antibody; CD140b antigen antibody; IBGC4 antibody; IMF1 antibody; JTK12 antibody; OTTHUMP00000160528 antibody; Beta platelet derived growth factor receptor antibody; Beta-type platelet-derived growth factor receptor antibody; CD 140B antibody; CD140 antigen-like family member B antibody; CD140b antibody; CD140b antigen antibody; IBGC4 antibody; IMF1 antibody; JTK12 antibody; OTTHUMP00000160528 antibody; PDGF R beta antibody; PDGF-R-beta antibody; PDGFR 1 antibody; PDGFR antibody; PDGFR beta antibody; PDGFR1 antibody; PDGFRB antibody; PGFRB_human antibody; platelet derived growth factor receptor 1 antibody; platelet derived growth factor receptor beta antibody; platelet derived growth factor receptor beta polypeptide antibody;	WB	Mouse
	Phospho-PDGFR beta (Y1021) Antibody (YA6722) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-PDGFR beta (Y1021).

HY-P80447

	CD31 Antibody (YA541) 3 Publications Verification Adhesion molecule antibody; CD31 antibody; CD31 antigen antibody; CD31 EndoCAM antibody; EndoCAM antibody; FLJ34100 antibody; FLJ58394 antibody; GPIIA antibody; GPIIA' antibody; PECA1 antibody; PECA1_human antibody; Pecam 1 antibody; PECAM 1 CD31 EndoCAM antibody; PECAM antibody; PECAM-1 antibody; Pecam1 antibody; platelet and endothelial cell adhesion molecule 1 antibody; platelet endothelial cell adhesion molecule antibody; platelet/endothelial cell adhesion molecule 1 antibody;	WB, IHC-P, ICC/IF, IP, FC	Human
	CD31 Antibody (YA541) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD31.

HY-P86806

	CD41 Antibody (YA6499) antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; antigen CD41 antibody; BDPLT16 antibody; BDPLT2 antibody; CD41 antibody; CD41B antibody; form 2 antibody; GP2B antibody; GPalpha IIb antibody; GPIIb antibody; GT antibody; GTA antibody; HPA3 antibody; Integrin alpha 2b antibody; Integrin alpha IIb antibody; Integrin alpha-IIb light chain antibody; Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) antibody; ITA2B_human antibody; Itga2b antibody; ITGAB antibody; platelet fibrinogen receptor, alpha subunit antibody; platelet glycoprotein IIb of IIb/IIIa complex antibody; platelet membrane glycoprotein IIb antibody; platelet specific antigen BAK antibody; PPP1R93 antibody;	IHC-P, FC, ICC/IF	Mouse
	CD41 Antibody (YA6499) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD41.

HY-P87002

	P2Y12 Antibody (YA6695) 1 Publications Verification ADP glucose receptor antibody; ADP-glucose receptor antibody; ADPG R antibody; ADPG-R antibody; ADPGR antibody; BDPLT8 antibody; G protein coupled receptor SP1999 antibody; Gi coupled ADP receptor HORK 3 antibody; Gi coupled ADP receptor HORK3 antibody; HORK 3 antibody; ADP glucose receptor antibody; ADP-glucose receptor antibody; ADPG R antibody; ADPG-R antibody; ADPGR antibody; BDPLT8 antibody; G protein coupled receptor SP1999 antibody; Gi coupled ADP receptor HORK 3 antibody; Gi coupled ADP receptor HORK3 antibody; HORK 3 antibody; HORK3 antibody; P2RY 12 antibody; P2RY12 antibody; P2T(AC) antibody; P2Y 12 antibody; P2Y purinoceptor 12 antibody; P2Y(12)R antibody; P2Y(AC) antibody; P2Y(ADP) antibody; P2Y(cyc) antibody; P2Y12 antibody; P2Y12 platelet ADP receptor antibody; P2Y12_human antibody; platelet ADP receptor antibody; Purinergic receptor P2RY12 antibody; Purinergic receptor P2Y G protein coupled 12 antibody; Purinergic receptor P2Y12 antibody; Putative G protein coupled receptor antibody; SP 1999 antibody; SP1999 antibody;	IHC-F, IHC-P	Mouse, Rat
	P2Y12 Antibody (YA6695) is a Rat -derived and non-conjugated IgG1 monoclonal antibody, targeting to P2Y12.

HY-P86829

	CXCL1/GRO alpha Antibody (YA6522) C-X-C motif chemokine 1 antibody; Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody; chemokine (C-X-C motif) ligand 1 antibody; CINC-1 antibody; CXCL1 antibody; Cytokine-induced neutrophil chemoattractant 1 antibody; Fibroblast secretory protein antibody; Fsp antibody; Gro 1 antibody; Gro A antibody; C-X-C motif chemokine 1 antibody; Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody; chemokine (C-X-C motif) ligand 1 antibody; CINC-1 antibody; CXCL1 antibody; Cytokine-induced neutrophil chemoattractant 1 antibody; Fibroblast secretory protein antibody; Fsp antibody; Gro 1 antibody; Gro A antibody; Gro antibody; GRO protein, alpha antibody; GRO-alpha(1-73) antibody; GRO-alpha(6-73) antibody; Gro1 antibody; GRO1 oncogene (melanoma growth stimulating activity, alpha) antibody; GRO1 oncogene (melanoma growth-stimulating activity) antibody; Gro1 oncogene antibody; GROa antibody; GROA_human antibody; Growth-regulated alpha protein antibody; KC antibody; KC chemokine, mouse, homolog of antibody; melanoma growth stimulatory activity alpha antibody; Melanoma growth stimulatory activity antibody; Melanoma growth stimulatory activity, alpha antibody; MGSA alpha antibody; MGSA antibody; MGSA-a antibody; N51 antibody; NAP-3 antibody; NAP3 antibody; Neutrophil-activating protein 3 antibody; platelet-derived growth factor-inducible protein KC antibody; Scyb 1 antibody; Scyb1 antibody; Secretory protein N51 antibody; Small inducible cytokine subfamily B, member 1 antibody;	WB	Human
	CXCL1/GRO alpha Antibody (YA6522) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CXCL1/GRO alpha.

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Host
Reactivity
Application
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Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
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Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-174935

DBCO-PEG1000-NHS		DBCO
DBCO-PEG1000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935A

DBCO-PEG2000-NHS		DBCO
DBCO-PEG2000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935C

DBCO-PEG5000-NHS		DBCO
DBCO-PEG5000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935B

DBCO-PEG3400-NHS		DBCO
DBCO-PEG3400-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

HY-174935D

DBCO-PEG10000-NHS		DBCO
DBCO-PEG10000-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material .

Cat. No.	Product Name		Classification

HY-W010918

Adenosine 5'-diphosphate 5+ Cited Publications Adenosine diphosphate; ADP		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-153999A

Rondaptivon pegol sodium BT200 sodium		Aptamers
Rondaptivon pegol (BT200) sodium is an aptamer targeting von Willebrand factor (VWF), with an EC₅₀ of 33 nM in humans. Rondaptivon pegol sodium effectively alleviates acute myocardial ischemia-reperfusion injury in mice by inhibiting VWF activity, reducing microvascular obstruction, inflammatory responses and cardiomyocyte apoptosis (apoptosis). Rondaptivon pegol sodium inhibits the binding of VWF to platelet glycoprotein GPIb, thereby preventing arterial thrombosis in cynomolgus monkeys. Rondaptivon pegol sodium can be used in research related to arterial thrombosis, stroke, myocardial infarction and myocardial ischemia-reperfusion injury .

HY-W010791

Adenosine 5'-diphosphate sodium salt 5+ Cited Publications		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P_2T-purinergic receptors .

HY-153999

Rondaptivon pegol BT200		Aptamers
Rondaptivon pegol (BT200) is an aptamer targeting von Willebrand factor (VWF), with an EC₅₀ of 33 nM in humans. Rondaptivon pegol effectively alleviates acute myocardial ischemia-reperfusion injury in mice by inhibiting VWF activity, reducing microvascular obstruction, inflammatory responses and cardiomyocyte apoptosis (apoptosis). Rondaptivon pegol inhibits the binding of VWF to platelet glycoprotein GPIb, thereby preventing arterial thrombosis in cynomolgus monkeys. Rondaptivon pegol can be used in research related to arterial thrombosis, stroke, myocardial infarction and myocardial ischemia-reperfusion injury .

HY-D0882

Adenosine 5'-diphosphate dicyclohexylammonium		Nucleotide Analogs Adenine Nucleotide
Adenosine 5'-diphosphate dicyclohexylammonium is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate dicyclohexylammonium induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors .

HY-W783254

C18 LPA PA(18:0e/0:0)		Phospholipids
C18 LPA (PA(18:0e/0:0)) is a water-soluble phospholipid that functions as a signaling molecule, influencing various cellular responses through G protein-coupled receptors (GPCRs). It is known to promote smooth muscle contraction, cytoskeletal rearrangement, and chemotaxis, while also playing a role in neurotransmitter release, cell proliferation, platelet aggregation, and Ca2+ mobilization. Elevated levels of C18 LPA in human plasma are associated with ovarian cancer and atherosclerosis, suggesting its potential as a biomarker for ovarian cancer.

HY-174553

Human PDGFA mRNA		mRNA
Human PDGFA mRNA encodes the human platelet derived growth factor A (PDGFA) protein, a member of the platelet-derived growth factor family. PDGFA plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.

HY-174552

Human PDGFB mRNA		mRNA
Human PDGFB mRNA encodes the human platelet derived growth factor B (PDGFB) protein, a member of the platelet-derived growth factor family. PDGFB plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.

HY-174550

Human PDGFD mRNA		mRNA
Human PDGFD mRNA encodes the human platelet derived growth factor D (PDGFD) protein, a member of the platelet-derived growth factor family. PDGFD plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.

HY-174551

Human PDGFC mRNA		mRNA
Human PDGFC mRNA encodes the human platelet derived growth factor C (PDGFC) protein, a member of the platelet-derived growth factor family. PDGFC plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.

HY-174548

Human PDGFRB mRNA		mRNA
Human PDGFRB mRNA encodes the human platelet derived growth factor receptor beta (PDGFRB) protein, a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRB is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton.

HY-174549

Human PDGFRA mRNA		mRNA
Human PDGFRA mRNA encodes the human platelet derived growth factor receptor alpha (PDGFRA) protein, a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA may play a role in organ development, wound healing, and tumor progression.

HY-174546

Human PECAM1 mRNA		mRNA
Human PECAM1 mRNA encodes the human platelet and endothelial cell adhesion molecule 1 (PECAM1) protein, a member of the immunoglobulin superfamily. PECAM1 is likely involved in leukocyte migration, angiogenesis, and integrin activation.

HY-174509

Human VEGFB mRNA		mRNA
Human VEGFB mRNA encodes the human vascular endothelial growth factor B (VEGFB) protein, a member of the platelet-derived growth factor (PDGF)/ vascular endothelial growth factor (VEGF) family. VEGFB is a growth factor for endothelial cells.

HY-174507

Human VEGFD mRNA		mRNA
Human VEGFD mRNA encodes the human vascular endothelial growth factor D (VEGFD) protein, a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is structurally and functionally similar to vascular endothelial growth factor C (VEGFC).

HY-174508

Human VEGFC mRNA		mRNA
Human VEGFC mRNA encodes the human vascular endothelial growth factor C (VEGFC) protein, a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFC promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels.

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