Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
immunomodulatory mechanism
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "immunomodulatory mechanism" in MCE Product Catalog:
7
1
Category:
Triterpenes Terpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-W746708
CAS No.: 79335-75-4
Target:
Research Areas:
FK-565 is a synthetic immunomodulatory peptide with a nucleotide oligomerization domain-1 (NOD1) ligand. FK-565 can activate macrophages, NK cells, and peritoneal exudative cells, enhancing the innate immune response. FK-565 has antiviral activity against a variety of viruses in vivo, and its effect is achieved through immunomodulation rather than direct viral inhibition. FK-565 can induce mouse models of arteritis and coronary arteritis (Kawasaki disease-like disease) through a NOD1-mediated mechanism. FK-565 can be used for research on viral infections and inflammatory vascular diseases .
Category:
Cat. No.: HY-P2170
CAS No.: 316805-65-9
Synonyms: XOMA-629
Target:
Research Areas:
Cat. No.: HY-137007
CAS No.: 1496553-39-9
Target:
Research Areas:
SMA-12b is a small molecule analogue of the parasitic worm compound ES-62. SMA-12b has immunomodulatory activity, acting by regulating the expression of multiple inflammatory response genes, especially those associated with inflammatory bodies. SMA-12b significantly reduces the expression of cytokine IL-1β associated with inflammatory bodies and inhibites the production of IL-1β through a mechanism mediated by NRF2. SMA-12b can be used in the study of rheumatoid arthritis (RA) and other autoimmune diseases .
Cat. No.: HY-L255
72 compounds
Dipeptide compounds have attracted extensive attention in drug discovery and life science research due to their simple structures, ease of modification, and favorable biocompatibility. As small peptides composed of two amino acids, dipeptides exhibit diverse biological activities, including anti-inflammatory, antioxidant, antimicrobial, anticancer, and immunomodulatory effects, showing significant application potential in metabolic disorders, neurological diseases, and cancer research. Compared with traditional small molecules, dipeptide compounds possess favorable target-binding properties and high structural plasticity, making them valuable tools for drug screening and mechanism studies.
The MCE Dipeptide Compound Library contains 72 dipeptide compounds and can be applied to peptide drug discovery and development.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
