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intermolecular hydrogen bonds

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Peptides

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W039897
    Methyl α-D-mannopyranoside
    1 Publications Verification

    α-Methyl-D-mannoside

    Environmental Pollutants Bacterial Infection
    Methyl α-D-mannopyranoside (α-Methyl-D-mannoside) is a methyl glycoside derivative and conformational stabilizer of α-D-mannopyranose. The glycosidic bond conformation of Methyl α-D-mannopyranoside is significantly affected by the environment. In aqueous solution, Methyl α-D-mannopyranoside stabilizes into a trans conformation via intermolecular hydrogen bonds; in the gas phase, however, steric interactions drive Methyl α-D-mannopyranoside to prefer a clockwise gauche conformation. Methyl α-D-mannopyranoside also serves as a major component of secondary cell wall polymers in some bacteria and an active precursor site for virus-targeted glycoproteins. Methyl α-D-mannopyranoside acts as an acceptor substrate for alternansucrase, mediating the transfer of D-glucopyranosyl groups to generate a variety of glycosylated oligosaccharide products, with methyl α-D-glucopyranosyl-(1→6)-α-D-mannopyranoside as the main component. Methyl α-D-mannopyranoside is applicable to studies on bacterial pathogenic mechanisms associated with mannose-specific fimbrial lectins .
    Methyl α-D-mannopyranoside
  • HY-133022

    (E)-2-Undecenoic acid; (E)-Undec-2-enoic acid

    Drug Isomer Metabolic Disease
    trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O .
    trans-2-Undecenoic acid
  • HY-133022R

    (E)-2-Undecenoic acid (Standard); (E)-Undec-2-enoic acid (Standard)

    Reference Standards Drug Isomer Metabolic Disease
    trans-2-Undecenoic acid (Standard) is the analytical standard of trans-2-Undecenoic acid. This product is intended for research and analytical applications. trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O[1].
    trans-2-Undecenoic acid (Standard)
  • HY-W020018

    Biochemical Assay Reagents Others
    N-Methylacetamide is a hydrogen bond-forming agent that mimics the intermolecular interactions of intrinsically disordered proteins. N-Methylacetamide is used to investigate the hydration properties of peptide bonds, peptide bond-water interactions, and the aggregation of intrinsically disordered proteins .
    N-Methylacetamide
  • HY-P11593

    Tau Protein Neurological Disease
    D-TLKIVWC is a tau fibril disaggregator. D-TLKIVWC has low immunogenicity and anti-degradation properties. D-TLKIVWC disrupts intermolecular hydrogen bonds of tau via a stress-release mechanism. D-TLKIVWC can be used in the research of amyloid diseases such as Alzheimer's disease .
    D-TLKIVWC
  • HY-173368

    PI3K Cancer
    Antiproliferative agent-67 (Compound 5g) is a PI3K inhibitor with a selectivity index SI of 7.72 for breast cancer cells (MCF-7). Antiproliferative agent-67 inhibits the activity of PI3K protein by forming hydrogen bonds and intermolecular hydrophobic forces with it, exerting anti - proliferative activity against breast cancer cells (MCF-7), and can be used in the research of breast cancer .
    Antiproliferative agent-67
  • HY-185227

    Ephrin Receptor Src Bcr-Abl EGFR Cancer
    EphB4-IN-1 is a selective EphB4 tyrosine kinase inhibitor with IC50 values of 0.16-0.30 μM. EphB4-IN-1 binds to the ATP binding site of EphB4 in a DFG-in conformation, forming four stable intermolecular hydrogen bonds. EphB4-IN-1 also inhibits Src, Abl1, Lck, and EGFR kinases. EphB4-IN-1 inhibits EphB4 autophosphorylation. EphB4-IN-1 can be used for the research of cancer, such as non small cell lung cancer .
    EphB4-IN-1
  • HY-W077690

    Bacterial Infection
    3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione is an metal chelating agent and anti-bacterial agent. 3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione shows inhibitory activity against gram-positive and gram-negative bacterial strains .
    3-(2-Hydroxyethyl)quinazoline-2,4(1H,3H)-dione

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