1. Neuronal Signaling
  2. Tau Protein
  3. D-TLKIVWC

D-TLKIVWC is a tau fibril disaggregator. D-TLKIVWC has low immunogenicity and anti-degradation properties. D-TLKIVWC disrupts intermolecular hydrogen bonds of tau via a stress-release mechanism. D-TLKIVWC can be used in the research of amyloid diseases such as Alzheimer's disease.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

D-TLKIVWC

D-TLKIVWC Chemical Structure

CAS No. : 3105302-84-6

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Description

D-TLKIVWC is a tau fibril disaggregator. D-TLKIVWC has low immunogenicity and anti-degradation properties. D-TLKIVWC disrupts intermolecular hydrogen bonds of tau via a stress-release mechanism. D-TLKIVWC can be used in the research of amyloid diseases such as Alzheimer's disease[1].

In Vitro

D-TLKIVWC (500 μM; 48 h) disassembles AD-tau fibrils and recombinant tau K18+ fibrils in vitro without requiring disulfide bond formation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

862.09

Formula

C41H67N9O9S

CAS No.
Sequence

d-{Thr-Leu-Lys-Ile-Val-Trp-Cys}

Sequence Shortening

d-{TLKIVWC}

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
D-TLKIVWC
Cat. No.:
HY-P11593
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