30 Results for "

leukemia inhibitory factor

" in MedChemExpress (MCE) Product Catalog:
Products (30)

30 Results for "leukemia inhibitory factor" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-120142
CAS No.: 2012591-09-0
Purity:  99.09%
Target:  

Apoptosis

Research Areas:  

Cancer

EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a Kd of 10.2 nM, which directly interacts with LIFR to effectively block LIF/LIFR interactions . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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9
9 Cited Publications
Cat. No.: HY-100949
CAS No.: 2016795-77-8
Purity:  99.11%
Research Areas:  

Cancer

EC330 is a leukemia inhibitory factor (LIF) inhibitor. EC330 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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5
5 Cited Publications
Cat. No.: HY-P7084
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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5
5 Cited Publications
Cat. No.: HY-P7049
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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4
4 Cited Publications
Cat. No.: HY-P73276
Purity:  ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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1
1 Cited Publications
Cat. No.: HY-P78324
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-N3097
CAS No.: 18836-52-7
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .
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Cat. No.: HY-103471
CAS No.: 1086639-59-9
Purity:  ≥95.0%
Target:  

FAK Interleukin Related

Research Areas:  

Cancer

Y11 inhibits the autophosphorylation of FAK1 by blocking the phosphorylation of Y397. Y11 increases the expression level of IL-6. Y11 is applicable for cancer research .
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Cat. No.: HY-N11011
CAS No.: 57423-72-0
Withaphysalin A is a withanolide compound with anti-inflammatory and antioxidant activities. Withaphysalin A inhibits LPS (HY-D1056)-induced nuclear translocation of NF-κB p65, as well as phosphorylation of STAT3, ERK, JNK and p38 MAPK. Withaphysalin A upregulates the expression of HO-1. Withaphysalin A inhibits LPS-induced production of NO, PGE2, IL-1β, IL-6 and TNF-α. Withaphysalin A downregulates LPS-induced expression of iNOS and COX-2. Withaphysalin A interacts with B-cell activating factor protein (BAFF) to exert inhibitory effects. Withaphysalin A exhibits ELOVL6 inhibitory activity. Withaphysalin A can be used in the research of inflammatory diseases, nephrotic syndrome and chronic myeloid leukemia .
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Cat. No.: HY-N3097R
CAS No.: 18836-52-7
Pellitorine (Standard) is the analytical standard of Pellitorine (HY-N3097). Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria.
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Cat. No.: HY-P703857
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-184832
CAS No.: 1246751-68-7
Synonyms: Peptide 021
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

P021 (Peptide 021) is an orally active, blood-brain barrier penetrant neurotrophic/neurogenic pentapeptide derived from the most active region of ciliary neurotrophic factor (CNTF). P021 competitively inhibits leukemia inhibitory factor (LIF) and promotes BDNF transcription. P021 targets neurogenesis and synaptic plasticity. P021 prevents neurodegeneration, Amyloid-β pathology, tau protein pathology and cognitive deficits, rescues episodic memory impairment and reduces mortality in 3xTg-AD mice. P021 is applicable to the research of Alzheimer's disease .
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Cat. No.: HY-P700135AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-P700220AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-P73280
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-P73277
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-P73279
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-P73278
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIF; Hepatocyte-Stimulating factor III; LIF Interleukin 6 Family Cytokine; Differentiation-Inducing factor; HILDA; Melanoma-Derived LPL Inhibitor; leukemia inhibitory factor; Human Interleukin In DA Cells; CDF; D factor; DIA; MLPLI; Differentiation Inhibi
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Cat. No.: HY-P811345
Synonyms: CD118, leukemia inhibitory factor receptor, LIF receptor, LIF-R, LIFR

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-P75907
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LIFR; CD118 Antigen; LIF Receptor Subunit Alpha; LIF-R; leukemia inhibitory factor Receptor; LIF Receptor; CD118; SJS2; leukemia inhibitory factor Receptor Alpha; STWS; LIF Receptor Alpha; SWS
Species:  
Rat
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