1 Result for "

macroptery

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "macroptery" in MCE Product Catalog:

Precocene II
Precocene II
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Referencia número: HY-122940
No. CAS: 644-06-4
Pureza:  99.95%
Synonyms: Ageratochromene
Category:  

Natural Products Animals Other Diseases Disease Research Fields

Target:  

Endogenous Metabolite

Precocene II (Ageratochromene) is a plant larva hormone antagonists that inhibits the biosynthesis of juvenile hormone. Precocene II inhibits corpora allata function and downregulates juvenile hormone levels, while exerting multiple effects including inducing precocious metamorphosis, forming macropterous morphs, inhibiting ovarian growth, producing cytotoxicity, disrupting insect development, and causing sterility and kidney damage. Precocene II blocks normal nymphal development, causes renal tubular damage and increases blood urea nitrogen levels, and also blocks juvenile hormone biosynthesis in vitro. Precocene II undergoes oxidative metabolism catalyzed by NADPH-dependent monooxygenase to generate a variety of metabolites. Precocene II can be applied in studies related to insect growth regulation and nephrotoxicity .
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