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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
mental retardation
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "mental retardation" in MCE Product Catalog:
2
CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe .
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1
1 Cited Publications
Cat. No.: HY-P702820
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRBN; MRT2; Prev. MRT2A; Protein X 0001; Protein Cereblon; Cereblon; mental retardation, Non-Syndromic, Autosomal Recessive, 2A
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P70366
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MECP2; Methyl CpG Binding Protein 2 Isoform 8; Prev. MRX16; mental retardation, X-Linked 16; Prev. MRX79; mental retardation, X-Linked 79; Prev. RTT; Rett Syndrome; Methyl-CpG-Binding Protein 2; AUTSX3; MeCp-2 Protein; MRXS13; Methyl CpG Binding Protein 2
Species:
Human
Source:
HEK293
Synonyms: RG-7816; RO-7017773
Target:
Research Areas:
Alogabat is a positive allosteric modulator (PAM) and agonist (Ki <100 nM) of the GABAA α5 receptor, targeting the α5β3γ2 subunit with a Ki of 8.7 nM. Alogabat increases the expression level of α5β3γ2 in oocytes (1.97-fold). GABAA has been implicated in cognitive impairment associated with central nervous system (CNS) disorders, brain cancer (including brain tumors such as medulloblastoma), and can be used in the study of mild cognitive impairment (MCI), amnestic MCI (aMCI), age-associated memory impairment (AAMI), age-related cognitive decline (ARCD), dementia, Alzheimer's disease (AD), prodromal AD, post-traumatic stress disorder (PTSD), schizophrenia, bipolar disorder, amyotrophic lateral sclerosis (ALS), cognitive impairment associated with cancer treatment, mental retardation, Parkinson's disease (PD), autism spectrum disorder, fragile X, Rett syndrome, obsessive-compulsive behavior, and substance addiction .
Target:
Research Areas:
ACDPP is a specific mGluR5 antagonist. ACDPP partially bolcks the increase of fragile X mental retardation protein (FMRP) caused by DHPG (HY-12598A) (group I mGluR Agonist) .
Cat. No.: HY-P705480
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FXR1; MYOPMIL; FMR1 Autosomal Homolog 1; MYORIBF; RNA-Binding Protein FXR1; CMYO9A; CDNA FLJ58644, Highly Similar To Fragile X mental retardation Syndrome-Related Protein 1; CMYO9B; Fragile X mental retardation Autosomal Homolog Variant P1K; CMYP9A; Fragi
Species:
Human
Source:
E. coli
Cat. No.: HY-P702818
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CRBN; MRT2; Prev. MRT2A; Protein X 0001; Protein Cereblon; Cereblon; mental retardation, Non-Syndromic, Autosomal Recessive, 2A
Species:
Human
Source:
HEK293
Cat. No.: HY-P78942
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: POLA1; N Syndrome (mental retardation, Malformations, Chromosome Breakage); Prev. POLA; Polymerase (DNA-Directed), Alpha (70kD); Prev. NSX; Polymerase (DNA Directed), Alpha; P180; Alternative Protein POLA1; Polymerase (DNA) Alpha 1, Catalytic Subunit; DNA
Species:
Others
Source:
E. coli
Cat. No.: HY-P702858
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HDAC8; RPD3; Prev. HDACL1; Histone Deacetylase-Like 1; Prev. MRXS6; Wilson-Turner X-Linked mental retardation Syndrome; Prev. WTS; Histone Deacetylase; Protein Decrotonylase HDAC8; CDA07; Protein Deacetylase HDAC8; CDLS5; KDAC8; Histone Deacetylase 8; HD8
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702825
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRBN; MRT2; Prev. MRT2A; Protein X 0001; Protein Cereblon; Cereblon; mental retardation, Non-Syndromic, Autosomal Recessive, 2A; DDB1; XPE-BF; Damage Specific DNA Binding Protein 1; XAP-1; DNA Damage-Binding Protein 1; XAP1; Xeroderma Pigmentosum Group E-
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702850
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRBN; MRT2; Prev. MRT2A; Protein X 0001; Protein Cereblon; Cereblon; mental retardation, Non-Syndromic, Autosomal Recessive, 2A; DDB1; XPE-BF; Damage Specific DNA Binding Protein 1; XAP-1; DNA Damage-Binding Protein 1; XAP1; Xeroderma Pigmentosum Group E-
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702851
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRBN; MRT2; Prev. MRT2A; Protein X 0001; Protein Cereblon; Cereblon; mental retardation, Non-Syndromic, Autosomal Recessive, 2A; DDB1; XPE-BF; Damage Specific DNA Binding Protein 1; XAP-1; DNA Damage-Binding Protein 1; XAP1; Xeroderma Pigmentosum Group E-
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P75144
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HDAC8; RPD3; Prev. HDACL1; Histone Deacetylase-Like 1; Prev. MRXS6; Wilson-Turner X-Linked mental retardation Syndrome; Prev. WTS; Histone Deacetylase; Protein Decrotonylase HDAC8; CDA07; Protein Deacetylase HDAC8; CDLS5; KDAC8; Histone Deacetylase 8; HD8
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P702902
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: KDM5C; Protein SmcX; Prev. JARID1C; Jumonji, AT Rich Interactive Domain 1C; Prev. SMCX; JmjC Domain-Containing Protein SMCX; Prev. MRX13; mental retardation, X-Linked 13; DXS1272E; Smcy Homolog, X-Linked (Mouse); XE169; Smcx Homolog, X Chromosome; [Histon
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P705597
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: WNK3; WNK Lysine Deficient Protein Kinase 3; PRKWNK3; Serine/Threonine‑Protein Kinase WNK3; Protein Kinase With No Lysine 3; Prieto X‑Linked mental retardation Syndrome; Protein Kinase, Lysine Deficient 3; Protein Kinase Lysine‑Deficient 3; KIAA1566; MRXS
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P706007
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CRBN; MRT2; Prev. MRT2A; Protein X 0001; Protein Cereblon; Cereblon; mental retardation, Non-Syndromic, Autosomal Recessive, 2A; DDB1; XPE-BF; Damage Specific DNA Binding Protein 1; XAP-1; DNA Damage-Binding Protein 1; XAP1; Xeroderma Pigmentosum Group E-
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P71529
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ST3GAL3; Alpha 2,3-ST 3; Prev. SIAT6; Sialyltransferase 6 (N-Acetyllacosaminide Alpha 2,3-Sialyltransferase); Prev. MRT12; mental retardation, Non-Syndromic, Autosomal Recessive, 12; ST3Gal III; Gal Beta-1,3(4)GlcNAc Alpha-2,3 Sialyltransferase; CMP-N-Ace
Species:
Human
Source:
E. coli
Cat. No.: HY-P74654
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: PAK3; HPAK3; Prev. MRX30; PAK-3; Prev. MRX47; Adriamycin Resistance-Associated; BPAK; mental retardation, X-Linked 47; P21 Protein (Cdc42/Rac)-Activated Kinase 3; P21-Activated Kinase 3; Serine/Threonine-Protein Kinase PAK 3; PAK3beta; P21 (CDKN1A)-Activa
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
