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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
methyltransferases (MTases)
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "methyltransferases (MTases)" in MCE Product Catalog:
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2
2 Cited Publications
Cat. No.: HY-W012078R
CAS No.: 838-07-3
Synonyms: 5-Methyldeoxycytidine (Standard)
Category:
Cat. No.: HY-W740027
CAS No.: 1160707-78-7
Synonyms: 5-Methyldeoxycytidine-d3
Target:
Research Areas:
Benzyl selenocyanate is a chemopreventive agent for various chemically induced tumors in animal models at both the initiation and postinitiation stages. Benzyl selenocyanate is an inhibitor of DNA (cytosine-5)-methyltransferase (Mtase), with an with an IC50 of 8.4 µM .
Cat. No.: HY-N12612
CAS No.: 59204-62-5
Category:
Target:
Cat. No.: HY-179048
CAS No.: 2766190-68-3
Target:
Research Areas:
MH44 is an efficient inhibitor targeting the SARS-CoV-2 nsp14 N7-methyltransferase (N7-MTase) with an IC50 of 19 nM. MH44 exhibits moderate antiviral effects in SARS-CoV-2-infected A549-hACE2 cells and shows certain cytotoxicity at higher concentrations. MH44 can be used in the research on anti-SARS-CoV-2 .
Cat. No.: HY-175228
RNA MTase-IN-1 (Compound 47) is a RNA methyltransferase (RNA MTase) inhibitor with an IC50 of 68 μM for 16S rRNA (m 1A1408) methyltransferase (NpmA). RNA MTase-IN-1 has a significant inhibitory activity against pathogen-associated aminoglycoside-resistance. RNA MTase-IN-1 can be used for resistant bacterial infections research .
Cat. No.: HY-150680
CAS No.: 2816165-02-1
Research Areas:
SARS-CoV-2 nsp14-IN-1 (Compound 3) is a prototypic bisubstrate inhibitor of SARS-CoV-2 Nsp14 MTase with an IC50 value of 0.061 μM. SARS-CoV-2 nsp14-IN-1 (Compound 3) has an excellent selectivity profile over a panel of human methyltransferases, can against apanel of 10 human MTases including histone lysine, proteinarginine, and DNA and RNA MTases .
Cat. No.: HY-143467
CAS No.: 2445585-37-3
SARS-CoV-IN-4 (compound 13) is a potent and specific inhibitor of SARS-CoV nsp14 N7-methyltransferase, with an IC50 of 0.6 μM (SARS-CoV nsp14) .
Cat. No.: HY-179722
Target:
Research Areas:
MTase-IN-2 (compound 32) is a potent NS5 methyltransferase inhibitor with IC50s of 2.14 μM and 2.01 μM against the Dengue virus (DENV3) MTase domain and Zika virus (ZIKV) NS5 MTase domain, respectively .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
